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Published in: International Journal of Colorectal Disease 12/2017

01-12-2017 | Original Article

Management of early anal cancer: need for guidelines and standardisation

Authors: Michael P. Jones, Susan Carroll, Jarad Martin, Richard Hillman, Andrew Grulich, Dianne O’Connell, Christopher Young, Isobel Mary Poynten

Published in: International Journal of Colorectal Disease | Issue 12/2017

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Abstract

Purpose

The optimal management of early squamous cell carcinoma of the anal canal (AC) is yet to be determined. This study investigated current practice in the management of early AC.

Methods

A patterns of care survey was completed by Australian surgeons and radiation oncologists. Specific topics addressed were as follows: geographical location of practice, staging of disease, treatment approaches to T1N0 tumours and grade 3 anal intra-epithelial neoplasia (AIN3) lesions, radiotherapy planning, toxicities, follow-up and clinical trial involvement.

Results

Sixty-four responses were obtained. For the management of T1N0 disease, half the respondents recommended standard dose chemo-radiotherapy (CRT) and one third recommended wide local excision (WLE). For the management of AIN3, half recommended WLE while a quarter advocated observation.

Conclusions

This study reveals a significant variation in the management of early AC. The development of guidelines specific to the treatment of early AC could standardise treatment while further research is required to define the optimal management of T1N0 AC and AIN.
Literature
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go back to reference Edge SB, Byrd DR, Compton CC, et al (2010) AJCC cancer staging manual, 7th edition Edge SB, Byrd DR, Compton CC, et al (2010) AJCC cancer staging manual, 7th edition
Metadata
Title
Management of early anal cancer: need for guidelines and standardisation
Authors
Michael P. Jones
Susan Carroll
Jarad Martin
Richard Hillman
Andrew Grulich
Dianne O’Connell
Christopher Young
Isobel Mary Poynten
Publication date
01-12-2017
Publisher
Springer Berlin Heidelberg
Published in
International Journal of Colorectal Disease / Issue 12/2017
Print ISSN: 0179-1958
Electronic ISSN: 1432-1262
DOI
https://doi.org/10.1007/s00384-017-2913-6

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