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Published in: International Journal of Colorectal Disease 7/2017

01-07-2017 | Short Communication

Failure of conservative treatment with Gastrografin® for adhesive small bowel obstruction after colorectal surgery

Authors: Jordi Miquel, Sebastiano Biondo, Esther Kreisler, Catalina Uribe, Loris Trenti

Published in: International Journal of Colorectal Disease | Issue 7/2017

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Abstract

Purpose

The aim of this study was to identify risk factors related with failure of conservative management of adhesive small bowel obstruction (ASBO) in patients with previous colorectal surgery.

Methods

Patients admitted with the diagnosis of ASBO after previous colorectal resection, were included. All patients underwent administration of Gastrografin®. Abdominal radiography was done after 24 h, to confirm the presence of contrast in colon (incomplete obstruction) or not (complete obstruction). Several factors were investigated to study their relationship with the failure of conservative management. Failure of conservative management was considered when emergency operation was needed to solve ASBO.

Results

Incomplete obstruction was observed in 174 episodes (93.0%) while in 13 (7.0%) was complete. One hundred seventy-one ASBO episodes (91.4%) responded successfully to nonoperative treatment and 16 (8.6%) required emergency surgery. Five patients needed bowel resection. Results on the diagnostic test with Gastrografin® showed a sensitivity of 75%, specificity of 99%, positive predictive value 92%, and negative predictive value 98%. Age over 75 years was the only predictive factor for failure of conservative management. The median waiting time from the radiologic confirmation of complete obstruction to surgery was higher in patients requiring bowel resection when compared to those who did not need resection.

Conclusions

The use of Gastrografin® in ASBO after colorectal resection is a safe and useful tool for the indication of conservative management. Age over 75 years is a predictive factor for need of surgery. Surgery should be performed no later than the following 24 h of confirmed complete obstruction.
Literature
1.
go back to reference Di Saverio S, Coccolini F, Galati M, Smerieri N, Biffl WL, Ansaloni L et al (2013) Bologna guidelines for diagnosis and management of adhesive small bowel obstruction (ASBO): 2013 update of the evidence-based guidelines from the world society of emergency surgery ASBO working group. World J Emerg Surg 8:42CrossRefPubMedPubMedCentral Di Saverio S, Coccolini F, Galati M, Smerieri N, Biffl WL, Ansaloni L et al (2013) Bologna guidelines for diagnosis and management of adhesive small bowel obstruction (ASBO): 2013 update of the evidence-based guidelines from the world society of emergency surgery ASBO working group. World J Emerg Surg 8:42CrossRefPubMedPubMedCentral
2.
go back to reference Vather R, Josephson R, Jaung R, Kahokehr A, Sammour T, Bissett I (2015) Gastrografin in prolonged postoperative ileus- a double-blinded randomized controlled trial. Ann Surg 262:23–30CrossRefPubMed Vather R, Josephson R, Jaung R, Kahokehr A, Sammour T, Bissett I (2015) Gastrografin in prolonged postoperative ileus- a double-blinded randomized controlled trial. Ann Surg 262:23–30CrossRefPubMed
3.
go back to reference Biondo S, Miquel J, Espin-Basany E, Sanchez JL, Golda T, Ferrer-Artola AM et al (2016) A double-blinded randomized clinical study on the therapeutic effect of gastrografin in prolonged postoperative ileus after elective colorectal surgery. World J Surg 40:206–214CrossRefPubMed Biondo S, Miquel J, Espin-Basany E, Sanchez JL, Golda T, Ferrer-Artola AM et al (2016) A double-blinded randomized clinical study on the therapeutic effect of gastrografin in prolonged postoperative ileus after elective colorectal surgery. World J Surg 40:206–214CrossRefPubMed
4.
go back to reference Biondo S, Parés D, Mora L, Martí-Ragué J, Kreisler E, Jaurrieta E (2003) Randomized clinical study of Gastrografin administration in patients with adhesive small bowel obstruction. Br J Surg 90:542–546CrossRefPubMed Biondo S, Parés D, Mora L, Martí-Ragué J, Kreisler E, Jaurrieta E (2003) Randomized clinical study of Gastrografin administration in patients with adhesive small bowel obstruction. Br J Surg 90:542–546CrossRefPubMed
5.
go back to reference Di Saverio S, Catena F, Ansaloni L, Gavioli M, Valentino M, Pinna AD (2008) Water-soluble contrast medium (gastrografin) value in adhesive small intestine obstruction (ASIO): a prospective, randomized, controlled, clinical trial. World J Surg 32:2293–2304CrossRefPubMed Di Saverio S, Catena F, Ansaloni L, Gavioli M, Valentino M, Pinna AD (2008) Water-soluble contrast medium (gastrografin) value in adhesive small intestine obstruction (ASIO): a prospective, randomized, controlled, clinical trial. World J Surg 32:2293–2304CrossRefPubMed
6.
go back to reference Branco BC, Barmparas G, Schnüriger B, Inaba K, Chan LS, Demetriades D (2010) Systematic review and meta-analysis of the diagnostic and therapeutic role of water-soluble contrast agent in adhesive small bowel obstruction. Br J Surg 97:470–478CrossRefPubMed Branco BC, Barmparas G, Schnüriger B, Inaba K, Chan LS, Demetriades D (2010) Systematic review and meta-analysis of the diagnostic and therapeutic role of water-soluble contrast agent in adhesive small bowel obstruction. Br J Surg 97:470–478CrossRefPubMed
7.
go back to reference Ceresoli M, Coccolini F, Catena F, Montori G, Di Saverio S, Sartelli M et al (2016) Water-soluble contrast agent in adhesive small bowel obstruction: a systematic review and meta-analysis of diagnostic and therapeutic value. World J Surg 211:1114–1125 Ceresoli M, Coccolini F, Catena F, Montori G, Di Saverio S, Sartelli M et al (2016) Water-soluble contrast agent in adhesive small bowel obstruction: a systematic review and meta-analysis of diagnostic and therapeutic value. World J Surg 211:1114–1125
8.
go back to reference Goussous N, Eiken PW, Bannon MP, Zielinski MD (2013) Enhancement of a small bowel obstruction model using the gastrografin® challenge test. J Gastrointest Surg 17:110–117CrossRefPubMed Goussous N, Eiken PW, Bannon MP, Zielinski MD (2013) Enhancement of a small bowel obstruction model using the gastrografin® challenge test. J Gastrointest Surg 17:110–117CrossRefPubMed
9.
go back to reference Komatsu I, Tokuda Y, Shimada G, Jacobs JL, Onodera H (2010) Development of a simple model for predicting need for surgery in patients who initially undergo conservative management for adhesive small bowel obstruction. Am J Surg 200:215–223CrossRefPubMed Komatsu I, Tokuda Y, Shimada G, Jacobs JL, Onodera H (2010) Development of a simple model for predicting need for surgery in patients who initially undergo conservative management for adhesive small bowel obstruction. Am J Surg 200:215–223CrossRefPubMed
10.
go back to reference Tanaka S, Yamamoto T, Kubota D, Matsuyama M, Uenishi T, Kubo S et al (2008) Predictive factors for surgical indication in adhesive small bowel obstruction. Am J Surg 196:23–27CrossRefPubMed Tanaka S, Yamamoto T, Kubota D, Matsuyama M, Uenishi T, Kubo S et al (2008) Predictive factors for surgical indication in adhesive small bowel obstruction. Am J Surg 196:23–27CrossRefPubMed
11.
go back to reference Zielinski MD, Eiken PW, Bannon MP, Heller SF, Lohse CM, Huebner M et al (2010) Small bowel obstruction-who needs an operation? A multivariate prediction model. World J Surg 34:910–919CrossRefPubMedPubMedCentral Zielinski MD, Eiken PW, Bannon MP, Heller SF, Lohse CM, Huebner M et al (2010) Small bowel obstruction-who needs an operation? A multivariate prediction model. World J Surg 34:910–919CrossRefPubMedPubMedCentral
12.
go back to reference Bueno-Lledó J, Barber S, Vaqué J, Frasson M, Garcia-Granero E, Juan-Burgueño M (2016) Adhesive small bowel obstruction: predictive factors of lack of response in conservative management with gastrografin. Dig Surg 33:26–32CrossRefPubMed Bueno-Lledó J, Barber S, Vaqué J, Frasson M, Garcia-Granero E, Juan-Burgueño M (2016) Adhesive small bowel obstruction: predictive factors of lack of response in conservative management with gastrografin. Dig Surg 33:26–32CrossRefPubMed
Metadata
Title
Failure of conservative treatment with Gastrografin® for adhesive small bowel obstruction after colorectal surgery
Authors
Jordi Miquel
Sebastiano Biondo
Esther Kreisler
Catalina Uribe
Loris Trenti
Publication date
01-07-2017
Publisher
Springer Berlin Heidelberg
Published in
International Journal of Colorectal Disease / Issue 7/2017
Print ISSN: 0179-1958
Electronic ISSN: 1432-1262
DOI
https://doi.org/10.1007/s00384-017-2786-8

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