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International Journal of Colorectal Disease

Published in:

01-09-2014 | Original Article

A temporary loop ileostomy affects renal function

Authors: Bodil Gessler, Eva Haglind, Eva Angenete

Published in: International Journal of Colorectal Disease | Issue 9/2014

Abstract

Purpose

The purpose of this study was to evaluate renal morbidity after a temporary loop ileostomy and to identify possible preoperative risk factors.

Method

Consecutive patients at four hospitals serving 1,520,000 inhabitants who received a temporary loop ileostomy and underwent subsequent closure were identified and retrospectively studied from 1 January 2007 until 28 February 2010. Serum creatinine levels were obtained 1 week before index surgery and 1 week before closure of the loop ileostomy. Estimated glomerular filtration rate (eGFR) was calculated using the CKD-EPI formula.

Results

Three hundred eight patients with median age of 64 were identified. The indication for the loop ileostomy was colorectal cancer (226), inflammatory bowel disease (41), diverticulosis (8), and other conditions (33). Median time until closure was 161 days (3–873). There was a decrease in eGFR at time of closure (89 vs. 83; p < 0.0001), and the number of patients with renal impairment (eGFR <60) increased (7.5 vs. 21 %, p < 0.0001). Preoperative risk factors for eGFR <60 at closure were age and hypertension.

Conclusions

This study found that a loop ileostomy is associated with a reduced renal function for most patients, especially for older and hypertensive patients. This should be considered before constructing a loop ileostomy, and perhaps another stoma should be chosen if possible in patients at risk. Evaluation of medications before discharge and early and frequent postoperative follow-up could also reduce the risk of a reduced renal function.

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Title: A temporary loop ileostomy affects renal function
Authors: Bodil Gessler
Eva Haglind
Eva Angenete
Publication date: 01-09-2014
Publisher: Springer Berlin Heidelberg
Published in: International Journal of Colorectal Disease / Issue 9/2014
Print ISSN: 0179-1958
Electronic ISSN: 1432-1262
DOI: https://doi.org/10.1007/s00384-014-1949-0

At a glance: The STEP trials

Springer Medicine

A temporary loop ileostomy affects renal function

Abstract

Purpose

Method

Results

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Purpose

Method

Results

Conclusions

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