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International Journal of Colorectal Disease

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01-05-2012 | Review

The management of primary small bowel and colon lymphoma—a review

Authors: Ceri Beaton, Mark Davies, John Beynon

Published in: International Journal of Colorectal Disease | Issue 5/2012

Abstract

Aims

The management of primary small bowel and colon lymphoma is controversial. A review of the literature was therefore undertaken to evaluate the evidence for the classification, staging, diagnosis, and treatment of primary small bowel and colon lymphoma and guide management.

Methods

A literature search was performed utilising Embase, Medline, and Pubmed and papers were evaluated on an individual basis.

Results

Consensus opinion favours the WHO classification scheme and the TNM staging systems for primary small bowel and colon lymphoma. CT enteroclysis and barium enterolysis are recommended for the diagnosis of primary small bowel lymphoma and capsule endoscopy and double-balloon enteroscopy maybe useful diagnostic tools. In terms of the diagnosis and staging of primary colonic lymphoma, the evidence is scarce and CT is to be recommended.

The mainstay of treatment for primary GI lymphoma is surgery and/or chemotherapy. For primary small bowel and colonic lymphoma, there was no definitive evidence regarding the benefits of either strategy; however, chemotherapy seemed to give a survival benefit over surgery alone for primary small bowel lymphoma and colonic lymphoma was skewed towards surgery plus chemotherapy due to the large number of patients presenting as an emergency.

Conclusion

Published data regarding the management of primary small bowel and colon lymphoma is very limited. Classification and staging should be standardised to enable accurate evaluation of investigations and treatments and a large RCT undertaken to compare chemotherapy and surgery. Currently, we would recommend that management should involve chemotherapy with surgery reserved for those with clinical indication.

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Title: The management of primary small bowel and colon lymphoma—a review
Authors: Ceri Beaton
Mark Davies
John Beynon
Publication date: 01-05-2012
Publisher: Springer-Verlag
Published in: International Journal of Colorectal Disease / Issue 5/2012
Print ISSN: 0179-1958
Electronic ISSN: 1432-1262
DOI: https://doi.org/10.1007/s00384-011-1309-2

At a glance: The STEP trials

Springer Medicine

The management of primary small bowel and colon lymphoma—a review

Abstract

Aims

Methods

Results

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Aims

Methods

Results

Conclusion

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