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International Journal of Colorectal Disease

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Open Access 01-10-2008 | Original Article

Diverticulosis and diverticulitis form no risk for polyps and colorectal neoplasia in 4,241 colonoscopies

Authors: M. M. Meurs-Szojda, J. S. Terhaar sive Droste, D. J Kuik, C. J. J. Mulder, R. J. F. Felt-Bersma

Published in: International Journal of Colorectal Disease | Issue 10/2008

Abstract

Background and aims

There are conflicting data concerning the association between diverticular disease and colorectal carcinoma (CRC). This study was performed to determine the prevalence and association of diverticulosis, diverticulitis, polyps, and CRC.

Materials and methods

In a cross-sectional, retrospective study, we analyzed the colonoscopy reports of complete colonoscopies and patho-histological results of all patients referred for colonoscopy in a period of 3 months in 18 hospitals in The Netherlands. Diverticulosis was defined as three or more diverticula present and diverticulitis as diverticulosis with inflammation. Polyps were also coded according to localization and size. Advanced neoplastic lesions were defined as polyps ≥10 mm in diameter and/or villous architecture and/or adenomas with high grade dysplasia and/or invasive cancer. Actual and previous described CRC were registered.

Results

A total of 4,241 patients were included in the study [1,996 (47%) male], mean age of 59 and range 18–95. Diverticula, diverticulitis, and polyps were seen in 1,052 (25%), 75 (2%), and 1,282 (30%) patients, respectively. No association was found between patients with polyps and those with and without diverticulosis (p = 0.478). Invasive adenocarcinoma and adenomas ≥10 mm were most frequently observed. CRC was present in 372 (9%) patients. Negative relation between diverticulosis and CRC and invasive adenocarcinoma was observed. No association was found between polyps and CRC and patients with diverticulitis and CRC. In conclusion, there is no relation between patients with diverticulosis and higher incidence of polyps or CRC when using age-stratified analysis. No increased risk for polyps or CRC was found in patients with diverticulitis.

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Title: Diverticulosis and diverticulitis form no risk for polyps and colorectal neoplasia in 4,241 colonoscopies
Authors: M. M. Meurs-Szojda
J. S. Terhaar sive Droste
D. J Kuik
C. J. J. Mulder
R. J. F. Felt-Bersma
Publication date: 01-10-2008
Publisher: Springer-Verlag
Published in: International Journal of Colorectal Disease / Issue 10/2008
Print ISSN: 0179-1958
Electronic ISSN: 1432-1262
DOI: https://doi.org/10.1007/s00384-008-0510-4

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Diverticulosis and diverticulitis form no risk for polyps and colorectal neoplasia in 4,241 colonoscopies

Abstract

Background and aims

Materials and methods

Results

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background and aims

Materials and methods

Results

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