Skip to main content
Top
Published in: International Journal of Colorectal Disease 9/2007

01-09-2007 | Original Article

Factors affecting continence after fistulotomy for intersphincteric fistula-in-ano

Authors: Takayuki Toyonaga, Makoto Matsushima, Takashi Kiriu, Nobuhito Sogawa, Hiroki Kanyama, Naomi Matsumura, Yasuhiro Shimojima, Tomoaki Hatakeyama, Yoshiaki Tanaka, Kazunori Suzuki, Masao Tanaka

Published in: International Journal of Colorectal Disease | Issue 9/2007

Login to get access

Abstract

Background and aims

This study was undertaken to determine the incidence of and risk factors for anal incontinence after fistulotomy for intersphincteric fistula-in-ano. We also evaluated the role of anal manometry in preoperative assessment of intersphincteric fistula.

Materials and methods

A prospective, observational study was undertaken in 148 patients who underwent fistulotomy for intersphincteric fistula between January and December 2004. Functional results were assessed by standard questionnaire and anal manometry. Possible factors predicting postoperative incontinence were examined by univariate and multivariate regression analyses.

Results

The mean follow-up period was 12 months. Postoperative anal incontinence occurred in 30 patients (20.3%), i.e., soiling in 6, incontinence for flatus in 27, and incontinence for liquid stool in 4. Fistulotomy significantly decreased maximum resting pressure (85.9 ± 20.4 to 60.2 ± 18.4 mmHg, P < 0.0001) and length of the high pressure zone (3.92 ± 0.69 to 3.82 ± 0.77 cm, P = 0.035), but it did not affect voluntary contraction pressure (164.7 ± 85.2 to 160.3 ± 84.8 mmHg, P = 0.2792). Multivariate analysis showed low voluntary contraction pressure and multiple previous drainage surgeries to be independent risk factors for postoperative incontinence.

Conclusion

Fistulotomy produces a satisfactory outcome in terms of eradicating sepsis and preserving function in the vast majority of patients with intersphincteric fistula with intact sphincters. However, sphincter-preserving treatment may be advocated for patients with low preoperative voluntary contraction pressure or those who have undergone multiple drainage surgeries. Preoperative anal manometry is useful in determining the proper surgical procedure.
Literature
1.
go back to reference Lunniss PJ, Kamm MA, Phillips RK (1994) Factors affecting continence after surgery for anal fistula. Br J Surg 81:1382–1385PubMedCrossRef Lunniss PJ, Kamm MA, Phillips RK (1994) Factors affecting continence after surgery for anal fistula. Br J Surg 81:1382–1385PubMedCrossRef
2.
go back to reference van Tets WF, Kuijpers HC (1994) Continence disorders after anal fistulotomy. Dis Colon Rectum 37:1194–1197PubMedCrossRef van Tets WF, Kuijpers HC (1994) Continence disorders after anal fistulotomy. Dis Colon Rectum 37:1194–1197PubMedCrossRef
3.
go back to reference Garcia-Aguilar J, Belmonte C, Wong WD, Goldberg SM, Madoff RD (1996) Anal fistula surgery. Factors associated with recurrence and incontinence. Dis Colon Rectum 39:723–729PubMedCrossRef Garcia-Aguilar J, Belmonte C, Wong WD, Goldberg SM, Madoff RD (1996) Anal fistula surgery. Factors associated with recurrence and incontinence. Dis Colon Rectum 39:723–729PubMedCrossRef
4.
go back to reference Hamalainen KP, Sainio AP (1997) Cutting seton for anal fistulas: high risk of minor control defects. Dis Colon Rectum 40:1443–1446; discussion 1447PubMedCrossRef Hamalainen KP, Sainio AP (1997) Cutting seton for anal fistulas: high risk of minor control defects. Dis Colon Rectum 40:1443–1446; discussion 1447PubMedCrossRef
5.
go back to reference Ho YH, Tan M, Leong AF, Seow-Choen F (1998) Marsupialization of fistulotomy wounds improves healing: a randomized controlled trial. Br J Surg 85:105–107PubMedCrossRef Ho YH, Tan M, Leong AF, Seow-Choen F (1998) Marsupialization of fistulotomy wounds improves healing: a randomized controlled trial. Br J Surg 85:105–107PubMedCrossRef
6.
go back to reference Mylonakis E, Katsios C, Godevenos D, Nousias B, Kappas AM (2001) Quality of life of patients after surgical treatment of anal fistula; the role of anal manometry. Colorectal Dis 3:417–421PubMedCrossRef Mylonakis E, Katsios C, Godevenos D, Nousias B, Kappas AM (2001) Quality of life of patients after surgical treatment of anal fistula; the role of anal manometry. Colorectal Dis 3:417–421PubMedCrossRef
7.
go back to reference Chang SC, Lin JK (2003) Change in anal continence after surgery for intersphincteral anal fistula: a functional and manometric study. Int J Colorectal Dis 18:111–115PubMedCrossRef Chang SC, Lin JK (2003) Change in anal continence after surgery for intersphincteral anal fistula: a functional and manometric study. Int J Colorectal Dis 18:111–115PubMedCrossRef
8.
go back to reference Garcia-Aguilar J, Davey CS, Le CT, Lowry AC, Rothenberger DA (2000) Patient satisfaction after surgical treatment for fistula-in-ano. Dis Colon Rectum 43:1206–1212PubMedCrossRef Garcia-Aguilar J, Davey CS, Le CT, Lowry AC, Rothenberger DA (2000) Patient satisfaction after surgical treatment for fistula-in-ano. Dis Colon Rectum 43:1206–1212PubMedCrossRef
9.
go back to reference Cavanaugh M, Hyman N, Osler T (2002) Fecal incontinence severity index after fistulotomy: a predictor of quality of life. Dis Colon Rectum 45:349–353PubMedCrossRef Cavanaugh M, Hyman N, Osler T (2002) Fecal incontinence severity index after fistulotomy: a predictor of quality of life. Dis Colon Rectum 45:349–353PubMedCrossRef
10.
go back to reference Malouf AJ, Buchanan GN, Carapeti EA, Rao S, Guy RJ, Westcott E, Thomson JP, Cohen CR (2002) A prospective audit of fistula-in-ano at St. Mark’s hospital. Colorectal Dis 4:13–19PubMedCrossRef Malouf AJ, Buchanan GN, Carapeti EA, Rao S, Guy RJ, Westcott E, Thomson JP, Cohen CR (2002) A prospective audit of fistula-in-ano at St. Mark’s hospital. Colorectal Dis 4:13–19PubMedCrossRef
11.
go back to reference Aguilar PS, Plasencia G, Hardy TG Jr, Hartmann RF, Stewart WR (1985) Mucosal advancement in the treatment of anal fistula. Dis Colon Rectum 28:496–498PubMedCrossRef Aguilar PS, Plasencia G, Hardy TG Jr, Hartmann RF, Stewart WR (1985) Mucosal advancement in the treatment of anal fistula. Dis Colon Rectum 28:496–498PubMedCrossRef
12.
go back to reference Athanasiadis S, Kohler A, Nafe M (1994) Treatment of high anal fistulae by primary occlusion of the internal ostium, drainage of the intersphincteric space, and mucosal advancement flap. Int J Colorectal Dis 9:153–157PubMedCrossRef Athanasiadis S, Kohler A, Nafe M (1994) Treatment of high anal fistulae by primary occlusion of the internal ostium, drainage of the intersphincteric space, and mucosal advancement flap. Int J Colorectal Dis 9:153–157PubMedCrossRef
13.
go back to reference Gustafsson UM, Graf W (2002) Excision of anal fistula with closure of the internal opening: functional and manometric results. Dis Colon Rectum 45:1672–1678PubMedCrossRef Gustafsson UM, Graf W (2002) Excision of anal fistula with closure of the internal opening: functional and manometric results. Dis Colon Rectum 45:1672–1678PubMedCrossRef
14.
go back to reference Koehler A, Risse-Schaaf A, Athanasiadis S (2004) Treatment for horseshoe fistulas-in-ano with primary closure of the internal fistula opening: a clinical and manometric study. Dis Colon Rectum 47:1874–1882PubMedCrossRef Koehler A, Risse-Schaaf A, Athanasiadis S (2004) Treatment for horseshoe fistulas-in-ano with primary closure of the internal fistula opening: a clinical and manometric study. Dis Colon Rectum 47:1874–1882PubMedCrossRef
15.
go back to reference Kreis ME, Jehle EC, Ohlemann M, Becker HD, Starlinger MJ (1998) Functional results after transanal rectal advancement flap repair of trans-sphincteric fistula. Br J Surg 85:240–242PubMedCrossRef Kreis ME, Jehle EC, Ohlemann M, Becker HD, Starlinger MJ (1998) Functional results after transanal rectal advancement flap repair of trans-sphincteric fistula. Br J Surg 85:240–242PubMedCrossRef
16.
go back to reference Lewis WG, Finan PJ, Holdsworth PJ, Sagar PM, Stephenson BM (1995) Clinical results and manometric studies after rectal flap advancement for infra-levator trans-sphincteric fistula-in-ano. Int J Colorectal Dis 10:189–192PubMedCrossRef Lewis WG, Finan PJ, Holdsworth PJ, Sagar PM, Stephenson BM (1995) Clinical results and manometric studies after rectal flap advancement for infra-levator trans-sphincteric fistula-in-ano. Int J Colorectal Dis 10:189–192PubMedCrossRef
17.
18.
go back to reference Jorge JM, Wexner SD (1993) Etiology and management of fecal incontinence. Dis Colon Rectum 36:77–97PubMedCrossRef Jorge JM, Wexner SD (1993) Etiology and management of fecal incontinence. Dis Colon Rectum 36:77–97PubMedCrossRef
19.
go back to reference Eckardt VF, Kanzler G (1993) How reliable is digital examination for the evaluation of anal sphincter tone? Int J Colorectal Dis 8:95–97PubMedCrossRef Eckardt VF, Kanzler G (1993) How reliable is digital examination for the evaluation of anal sphincter tone? Int J Colorectal Dis 8:95–97PubMedCrossRef
20.
go back to reference Cintron JR, Park JJ, Orsay CP, Pearl RK, Nelson RL, Sone JH, Song R, Abcarian H (2000) Repair of fistulas-in-ano using fibrin adhesive: long-term follow-up. Dis Colon Rectum 43:944–949; discussion 949–950PubMedCrossRef Cintron JR, Park JJ, Orsay CP, Pearl RK, Nelson RL, Sone JH, Song R, Abcarian H (2000) Repair of fistulas-in-ano using fibrin adhesive: long-term follow-up. Dis Colon Rectum 43:944–949; discussion 949–950PubMedCrossRef
21.
go back to reference Park JJ, Cintron JR, Orsay CP, Pearl RK, Nelson RL, Sone J, Song R, Abcarian H (2000) Repair of chronic anorectal fistulae using commercial fibrin sealant. Arch Surg 135:166–169PubMedCrossRef Park JJ, Cintron JR, Orsay CP, Pearl RK, Nelson RL, Sone J, Song R, Abcarian H (2000) Repair of chronic anorectal fistulae using commercial fibrin sealant. Arch Surg 135:166–169PubMedCrossRef
22.
go back to reference Johnson EK, Gaw JU, Armstrong DN (2006) Efficacy of anal fistula plug vs. fibrin glue in closure of anorectal fistulas. Dis Colon Rectum 49:371–376PubMedCrossRef Johnson EK, Gaw JU, Armstrong DN (2006) Efficacy of anal fistula plug vs. fibrin glue in closure of anorectal fistulas. Dis Colon Rectum 49:371–376PubMedCrossRef
23.
go back to reference O’Connor L, Champagne BJ, Ferguson MA, Orangio GR, Schertzer ME, Armstrong DN (2006) Efficacy of anal fistula plug in closure of Crohn’s anorectal fistulas. Dis Colon Rectum 49:1569–1573PubMedCrossRef O’Connor L, Champagne BJ, Ferguson MA, Orangio GR, Schertzer ME, Armstrong DN (2006) Efficacy of anal fistula plug in closure of Crohn’s anorectal fistulas. Dis Colon Rectum 49:1569–1573PubMedCrossRef
Metadata
Title
Factors affecting continence after fistulotomy for intersphincteric fistula-in-ano
Authors
Takayuki Toyonaga
Makoto Matsushima
Takashi Kiriu
Nobuhito Sogawa
Hiroki Kanyama
Naomi Matsumura
Yasuhiro Shimojima
Tomoaki Hatakeyama
Yoshiaki Tanaka
Kazunori Suzuki
Masao Tanaka
Publication date
01-09-2007
Publisher
Springer-Verlag
Published in
International Journal of Colorectal Disease / Issue 9/2007
Print ISSN: 0179-1958
Electronic ISSN: 1432-1262
DOI
https://doi.org/10.1007/s00384-007-0277-z

Other articles of this Issue 9/2007

International Journal of Colorectal Disease 9/2007 Go to the issue