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Published in: International Journal of Colorectal Disease 3/2006

01-04-2006 | Review

Late small bowel toxicity after adjuvant treatment for rectal cancer

Authors: Matthias Guckenberger, Michael Flentje

Published in: International Journal of Colorectal Disease | Issue 3/2006

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Abstract

Background

For locally advanced rectal cancer surgery as sole treatment results in poor local control and survival. After adjuvant radiotherapy for locally advanced rectal cancer, small bowel toxicity has been the most frequent and serious side effect. The gain in survival and local control was accompanied by severe late chronic toxicity reducing the benefit of adjuvant treatment.

Review

Clinical factors, pathology and treatment of late small bowel toxicity after adjuvant radiotherapy for locally advanced rectal cancer will be discussed. This review will focus on different surgical and radiotherapeutic means reducing the risk of late small bowel damage.
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Metadata
Title
Late small bowel toxicity after adjuvant treatment for rectal cancer
Authors
Matthias Guckenberger
Michael Flentje
Publication date
01-04-2006
Publisher
Springer-Verlag
Published in
International Journal of Colorectal Disease / Issue 3/2006
Print ISSN: 0179-1958
Electronic ISSN: 1432-1262
DOI
https://doi.org/10.1007/s00384-005-0765-y

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