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Pediatric Surgery International
Published in: Pediatric Surgery International 1/2023

01-12-2023 | Original Article

The clinical features of patients who underwent bladder augmentation of cloacal exstrophy and their functional outcomes: the results of a nationwide survey in Japan

Authors: Keisuke Yano, Koshiro Sugita, Takafumi Kawano, Masakazu Murakami, Toshio Harumatsu, Shun Onishi, Koji Yamada, Mitsuru Muto, Satoshi Ieiri, Masayuki Kubota

Published in: Pediatric Surgery International | Issue 1/2023

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Abstract

Purpose

Cloacal exstrophy (CE) patients may need bladder reconstruction after initially undergoing surgery to obtain continence and improve their quality of life. This study attempts to clarify the clinical features of CE patients who underwent bladder augmentation (BA) and their urinary functional outcomes based on a nationwide survey in Japan.

Methods

A questionnaire survey was conducted, and 150 CE patients were enrolled. Their clinical characteristics and urinary outcomes were reviewed.

Results

BA was performed in 52 patients (34.7%). Most cases underwent early bladder closure at initial surgery in neonate period. The age at the BA was performed 6.4 [6–9.0] years. Among them, the most used organ for BA was ileum (n = 30, 57.7%). Regarding the outcomes, the age when the renal function was evaluated was 14.0 [10.0–20.5] years and the serum creatinine level was 0.44 [0.36–0.60] (mg/dl). Clean intermittent catheterization was required in 37 (71.2%) patients. On the other hand, no dialysis or kidney transplantation was necessary in any of these patients.

Conclusion

The renal function and conditions of patients who underwent BA were relatively well preserved. Individualized management with a stepwise surgical approach for CE patients should thus be considered in the future.
Appendix
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Metadata
Title
The clinical features of patients who underwent bladder augmentation of cloacal exstrophy and their functional outcomes: the results of a nationwide survey in Japan
Authors
Keisuke Yano
Koshiro Sugita
Takafumi Kawano
Masakazu Murakami
Toshio Harumatsu
Shun Onishi
Koji Yamada
Mitsuru Muto
Satoshi Ieiri
Masayuki Kubota
Publication date
01-12-2023
Publisher
Springer Berlin Heidelberg
Published in
Pediatric Surgery International / Issue 1/2023
Print ISSN: 0179-0358
Electronic ISSN: 1437-9813
DOI
https://doi.org/10.1007/s00383-023-05512-z

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