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Pediatric Surgery International

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01-02-2021 | Trisomy 21 | Original Article

Predictive factors for the development of postoperative Hirschsprung-associated enterocolitis in children operated during infancy

Authors: Tsuyoshi Sakurai, Hiromu Tanaka, Naobumi Endo

Published in: Pediatric Surgery International | Issue 2/2021

Abstract

Purpose

The risk factors for postoperative Hirschsprung-associated enterocolitis (HAEC) are still incompletely understood, especially age at which surgery is performed. Therefore, the aim of this study was to identify the risk factors for the development of postoperative HAEC in children operated during infancy.

Methods

Thirty-five children who had undergone radical surgery for Hirschsprung disease (HD) during infancy were included in the study. They were divided into two groups; those who developed postoperative HAEC (HAEC, 14 patients) and those who did not (no HAEC, 21 patients). Their medical records were retrospectively reviewed for clinical details.

Results

Developing postoperative HAEC was significantly associated with long-segment HD (p = 0.020) and the age at radical surgery (p = 0.0241). No other factors had a significant association with postoperative HAEC. In the patients who developed postoperative HAEC (n = 14), those with Trisomy 21 had significantly longer hospitalizations than those without. Patients with long-segment HD had a higher hospitalization rate than those with short-segment HD.

Conclusion

This study clearly showed that long-segment HD and older age at radical surgery are risk factors for developing postoperative HAEC.

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Title: Predictive factors for the development of postoperative Hirschsprung-associated enterocolitis in children operated during infancy
Authors: Tsuyoshi Sakurai
Hiromu Tanaka
Naobumi Endo
Publication date: 01-02-2021
Publisher: Springer Berlin Heidelberg
Keyword: Trisomy 21
Published in: Pediatric Surgery International / Issue 2/2021
Print ISSN: 0179-0358
Electronic ISSN: 1437-9813
DOI: https://doi.org/10.1007/s00383-020-04784-z

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Predictive factors for the development of postoperative Hirschsprung-associated enterocolitis in children operated during infancy

Abstract

Purpose

Methods

Results

Conclusion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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