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Pediatric Surgery International
Published in: Pediatric Surgery International 3/2020

Open Access 01-03-2020 | Antibiotic | Review Article

Nonoperative treatment for nonperforated appendicitis in children: a systematic review and meta-analysis

Authors: Sonia Maita, Björn Andersson, Jan F. Svensson, Tomas Wester

Published in: Pediatric Surgery International | Issue 3/2020

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Abstract

Acute appendicitis is the most common surgical emergency in children. Nonoperative treatment of nonperforated acute appendicitis in children is an alternative to appendectomy. The purpose of this systematic review and meta-analysis was to determine the outcomes of nonoperative treatment of nonperforated acute appendicitis in children in the literature. Databases were searched to identify abstracts, using predefined search terms. The abstracts were reviewed by two independent reviewers and articles were selected according to inclusion and exclusion criteria. Data were extracted by the two reviewers and analyzed. The literature search yielded 2743 abstracts. Twenty-one articles were selected for analysis. The study design was heterogenous, with only one randomized controlled study. The symptoms resolved in 92% [95% CI (88; 96)] of the nonoperatively treated patients. Meta-analysis showed that an additional 16% (95% CI 10; 22) of patients underwent appendectomy after discharge from initial hospital stay. Complications and length of hospital stay was not different among patients treated with antibiotics compared with those who underwent appendectomy. Nonoperative treatment of nonperforated acute appendicitis children is safe and efficient. There is a lack of large randomized controlled trials to compare outcomes of nonoperative treatment with appendectomy.
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Metadata
Title
Nonoperative treatment for nonperforated appendicitis in children: a systematic review and meta-analysis
Authors
Sonia Maita
Björn Andersson
Jan F. Svensson
Tomas Wester
Publication date
01-03-2020
Publisher
Springer Berlin Heidelberg
Published in
Pediatric Surgery International / Issue 3/2020
Print ISSN: 0179-0358
Electronic ISSN: 1437-9813
DOI
https://doi.org/10.1007/s00383-019-04610-1

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