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01-03-2019 | Original Article

Efficacy of oral antibiotics in children with post-operative abscess from perforated appendicitis

Authors: Joseph A. Sujka, Katrina L. Weaver, Justin A. Sobrino, Ashwini Poola, Katherine W. Gonzalez, Shawn D. St. Peter

Published in: Pediatric Surgery International | Issue 3/2019

Abstract

Background

Post-operative intra-abdominal abscess (PIAA) is the most common complication after appendectomy for perforated appendicitis (PA). Typically, intravenous antibiotics by a peripherally inserted venous catheter are utilized to treat the abscess. We sought to evaluate the role of oral antibiotics in this population.

Methods

This is a retrospective review conducted of children between January 2005 and September 2015 with a PIAA. Demographics, clinical course, complications, and follow-up were analyzed using descriptive statistics. Comparative analysis was performed on those who were treated with oral vs IV antibiotics after diagnosis of PIAA.

Results

103 children were included. Days of symptoms prior to admission were 3.2 ± 2.3 days with a WBC of 17.9 ± 6.4. Median time to diagnosis of PIAA from appendectomy was 7 days (7, 10). Mean total length of stay was 10 ± 3.4 days. 42% were treated with oral antibiotics (n = 43) versus 58% IV antibiotics (n = 60) at the time of discharge. We found a significant increase in total length of hospital stay (9.1 vs 10.7, p = 0.02) and number of medical encounters required for treatment (3.4 vs 4.4, p ≤ 0.01) in the IV group.

Conclusions

PIAA treatment after appendectomy for PA can be treated with oral antibiotics with equivalent outcomes as IV antibiotic treatment, but with shorter length of hospitalizations and less medical encounters required.

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Title: Efficacy of oral antibiotics in children with post-operative abscess from perforated appendicitis
Authors: Joseph A. Sujka
Katrina L. Weaver
Justin A. Sobrino
Ashwini Poola
Katherine W. Gonzalez
Shawn D. St. Peter
Publication date: 01-03-2019
Publisher: Springer Berlin Heidelberg
Published in: Pediatric Surgery International / Issue 3/2019
Print ISSN: 0179-0358
Electronic ISSN: 1437-9813
DOI: https://doi.org/10.1007/s00383-018-4424-0

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Efficacy of oral antibiotics in children with post-operative abscess from perforated appendicitis

Abstract

Background

Methods

Results

Conclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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