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Pediatric Surgery International
Published in: Pediatric Surgery International 12/2017

01-12-2017 | Review Article

Update on investigations pertaining to the pathogenesis of biliary atresia

Authors: Alexandra Kilgore, Cara L. Mack

Published in: Pediatric Surgery International | Issue 12/2017

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Abstract

Biliary atresia is a devastating biliary disease of neonates that results in liver transplantation for the vast majority. The etiology of biliary atresia is unknown and is likely multifactorial, with components of genetic predisposition, environmental trigger and autoimmunity contributing to disease pathogenesis. This review highlights recent work related to investigations of disease pathogenesis in biliary atresia.
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Metadata
Title
Update on investigations pertaining to the pathogenesis of biliary atresia
Authors
Alexandra Kilgore
Cara L. Mack
Publication date
01-12-2017
Publisher
Springer Berlin Heidelberg
Published in
Pediatric Surgery International / Issue 12/2017
Print ISSN: 0179-0358
Electronic ISSN: 1437-9813
DOI
https://doi.org/10.1007/s00383-017-4172-6

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