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Pediatric Surgery International
Published in: Pediatric Surgery International 1/2017

01-01-2017 | Original Article

Neonatal gastrointestinal perforation in Japan: a nationwide survey

Authors: Masahito Sato, Yoshinori Hamada, Miyuki Kohno, Kazuya Ise, Keiichi Uchida, Hiromi Ogata, Hiroaki Masuyama, Yoshiki Morotomi, Masao Yasufuku, Motoshi Wada

Published in: Pediatric Surgery International | Issue 1/2017

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Abstract

Purpose

The purpose of this study is to identify the current clinical features of neonatal gastrointestinal perforation in Japan.

Methods

A questionnaire about cases of neonatal gastrointestinal perforation treated in recent 5 years was sent to participating institutions of the Japanese Society of Pediatric Surgeons (JSPS).

Results

Five hundred and thirty-six neonates with gastrointestinal perforation were treated. They consisted of 42 patients with gastric rupture/perforation (GR), 33 patients with intestinal atresia/stenosis (IA), 3 patients with malrotation (ML), 118 patients with necrotizing enterocolitis (NEC), 160 patients with focal intestinal perforation (FIP), 46 patients with meconium-related ileus (MRI), 77 patients with meconium peritonitis (MP), and 57 patients with other conditions. The total mortality rate was 20.5 %. The mortality rates of the patients with GR, IA, ML, NEC, FIP, MRI, and MP were 9.5, 9.1, 0, 33.1, 20.6, 28.2, and 9.1 %, respectively. In 263 cases involving extremely low-birth-weight neonates (ELBW), 108 died (mortality rate 41.1 %). The mortality rates for ELBW with GR, NEC, FIP, MRI, MP, and other conditions were 27.3 % (3/11), 58.5 % (48/82), 21.6 % (24/111), 70.6 % (24/34), 57.1 % (4/7), and 27.8 % (5/18), respectively.

Conclusions

The mortality rates for ELBW decreased from 62.8 % in the previous survey to 41.1 % by the time of this survey.
Literature
1.
Yagi M, Kohno M, Asagiru K et al (2015) Twenty-year trends in neonatal surgery based on a national wide Japanese surveillance program. Pediatr Surg Int 31:955–962CrossRefPubMed
2.
Committee of Academic Survey and Advanced Medical Science, the Japanese Society of Pediatric Surgeons and the Neonatal Nutrition Forum (2010) A survey regarding gastrointestinal perforation in extremely low-birth-weight neonates (in Japanase). J Jpn Soc Pediatr Surg 46:791–796
3.
Nagata K, Usui N, Kanamori Y et al (2013) The current profile and outcome of congenital diaphragmatic hernia: A nationwide survey in Japan. J Pediatr Surg 48:738–744CrossRefPubMed
4.
Kubota A, Shiraishi J, Kawahara H et al (2011) Meconium-related ileus in extremely low-birth weight neonates: etiological considerations from histology and radiology. Pediatr Int 53:887–891CrossRefPubMed
5.
Lin HC, Su BH, Chen AC et al (2005) Oral probiotics reduce the incidence and severity of necrotizing enterocolitis in very low birth weight infants. Pediatrics 115:1–4CrossRefPubMed
6.
7.
Lauriti G, Zani A, Aufieri R et al (2014) Incidence, prevention, and treatment of parenteral nutrition-associated cholestasis and intestinal failure-associated liver disease in infants and children: a systemic review. J Parenter Enteral Nutr 38:70–85CrossRef
8.
Kubota A, Mochizuki N, Shiraishi J et al (2013) Parenteral nutrition associated liver disease after intestinal perforation in extremely low-birth weight infants: consequent lethal portal hypertension. Pediatr Int 55:39–43CrossRefPubMed
9.
Gura KM, Parsons SK, Bechard LJ et al (2005) Use of a fish oil-based lipid emulsion to treat essential fatty acid deficiency in a soy allergic patient receiving parenteral nutrition. Clin Nutr 24:839–847CrossRefPubMed
10.
Gotoh M, Miyata H, Hashimoto H et al (2016) National clinical database feedback implementation for quality improvement of cancer treatment in Japan: from good to great through transparency. Surg Today 46:38–47CrossRefPubMed
11.
Nakagoe T, Miyata H, Gotoh M et al (2015) Surgical risk model for acute diffuse peritonitis based on a Japanese nationwide database: an initial report on the surgical and 30-day mortality. Surg Today 45:1233–1243CrossRefPubMed
Metadata
Title
Neonatal gastrointestinal perforation in Japan: a nationwide survey
Authors
Masahito Sato
Yoshinori Hamada
Miyuki Kohno
Kazuya Ise
Keiichi Uchida
Hiromi Ogata
Hiroaki Masuyama
Yoshiki Morotomi
Masao Yasufuku
Motoshi Wada
Publication date
01-01-2017
Publisher
Springer Berlin Heidelberg
Published in
Pediatric Surgery International / Issue 1/2017
Print ISSN: 0179-0358
Electronic ISSN: 1437-9813
DOI
https://doi.org/10.1007/s00383-016-3985-z

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