Skip to main content
Top
Published in: Pediatric Surgery International 8/2009

01-08-2009 | Original Article

Conservative surgical management of catheter infections in children on peritoneal dialysis

Authors: Francesco Macchini, Sara Testa, Alberto Valadè, Maurizio Torricelli, Ernesto Leva, Gianluigi Ardissino, Alberto Edefonti

Published in: Pediatric Surgery International | Issue 8/2009

Login to get access

Abstract

Introduction

Major indications for peritoneal dialysis catheter removal include chronic exit-site infection (ESI) or tunnel infection (TI). No consensus on the optimal treatment of these infections in children exists.

Patients

During the last 10 years, 13 patients (7 females, mean age 56 months) on peritoneal dialysis were treated for recurrent ESI (N: 4) or TI (N: 9). Staphylococcus aureus (12 patients) and Pseudomonas aeruginosa (1 patient) were isolated. All patients had a double-cuff straight Tenchkoff catheter and underwent the shaving of the external cuff, with a new tunnel tightly adherent to the catheter, and an exit-site in the opposite abdominal region. A mean follow-up of 31 months/catheter demonstrated no recurrence of ESI and TI.

Discussion

Little pediatric experience with cuff shaving exists: reported catheter salvage rates are 48–100%. In our experience, good results were obtained by shaving off the external cuff and re-creating a new tunnel, with a different course, strictly adherent to the catheter. This measure seems to guarantee an effective barrier against infections, while obviating the need of the external cuff.

Conclusions

Sometimes, in case of recurrent ESI or TI, the external cuff may facilitate the persistence of bacteria. A conservative surgical treatment offers good results in children.
Literature
1.
go back to reference Burkart JM (1996) Significance, epidemiology, and prevention of peritoneal dialysis catheter infections. Perit Dial Int 16(Suppl 1):S340–S346PubMed Burkart JM (1996) Significance, epidemiology, and prevention of peritoneal dialysis catheter infections. Perit Dial Int 16(Suppl 1):S340–S346PubMed
2.
go back to reference Bernardini J, Bender F, Florio T, Sloand J, Palmmontalbano L, Fried L, Piraino B (2005) Randomized, double-blind trial of antibiotic exit-site cream for prevention of exit-site infection in peritoneal dialysis patients. J Am Soc Nephrol 16(2):539–545PubMedCrossRef Bernardini J, Bender F, Florio T, Sloand J, Palmmontalbano L, Fried L, Piraino B (2005) Randomized, double-blind trial of antibiotic exit-site cream for prevention of exit-site infection in peritoneal dialysis patients. J Am Soc Nephrol 16(2):539–545PubMedCrossRef
3.
go back to reference Mc Chiu, Tong PC, Lai WM, Lau SC (2008) Peritonitis and exit-site infections in pediatric automated peritoneal dialysis. Perit Dial Int 28(3):S179–S182 Mc Chiu, Tong PC, Lai WM, Lau SC (2008) Peritonitis and exit-site infections in pediatric automated peritoneal dialysis. Perit Dial Int 28(3):S179–S182
4.
go back to reference Goldraich I, Mariano M, Rosito N, Goldraich N (1993) One-step peritoneal catheter replacement in children. Adv Perit Dial 9:325–328PubMed Goldraich I, Mariano M, Rosito N, Goldraich N (1993) One-step peritoneal catheter replacement in children. Adv Perit Dial 9:325–328PubMed
5.
go back to reference Chao SH, Tsai TJ (1996) Partial replantation of Tenckhoff catheters to treat intractable exit-site/tunnel infection. J Am Soc Nephrol 7(7):1085–1087PubMed Chao SH, Tsai TJ (1996) Partial replantation of Tenckhoff catheters to treat intractable exit-site/tunnel infection. J Am Soc Nephrol 7(7):1085–1087PubMed
6.
go back to reference Wu YM, Tsai MK, Chao SH, Tsai TJ, Chang KJ, Lee PH (1999) Surgical management of refractory exit-site/tunnel infection of Tenckhoff catheter: technical innovations of partial replantation. Perit Dial Int 19(5):451–454PubMed Wu YM, Tsai MK, Chao SH, Tsai TJ, Chang KJ, Lee PH (1999) Surgical management of refractory exit-site/tunnel infection of Tenckhoff catheter: technical innovations of partial replantation. Perit Dial Int 19(5):451–454PubMed
7.
go back to reference Khanna R, Twardowski ZJ (1996) Recommendations for treatment of exit-site pathology. Perit Dial Int 16(Suppl 3):S100–S104PubMed Khanna R, Twardowski ZJ (1996) Recommendations for treatment of exit-site pathology. Perit Dial Int 16(Suppl 3):S100–S104PubMed
9.
go back to reference Gloor HJ, Nichols WK, Sorkin MI, Prowant BF, Kennedy JM, Baker B, Nolph KD (1983) Peritoneal access and related complications in continuous ambulatory peritoneal dialysis. Am J Med 74(4):593–598PubMedCrossRef Gloor HJ, Nichols WK, Sorkin MI, Prowant BF, Kennedy JM, Baker B, Nolph KD (1983) Peritoneal access and related complications in continuous ambulatory peritoneal dialysis. Am J Med 74(4):593–598PubMedCrossRef
10.
go back to reference Lewis MA, Smith T, Roberts D (1996) Peritonitis, functional catheter loss and the sitting of the Dacron cuff in chronic peritoneal dialysis catheters in children. Eur J Pediatr Surg 6(5):285–287PubMedCrossRef Lewis MA, Smith T, Roberts D (1996) Peritonitis, functional catheter loss and the sitting of the Dacron cuff in chronic peritoneal dialysis catheters in children. Eur J Pediatr Surg 6(5):285–287PubMedCrossRef
11.
go back to reference Warady BA, Schaefer F, Holloway M, Alexander S, Kandert M, Piraino B, Salusky I, Tranaeus A, Divino J, Honda M, Mujais S, Verrina E, International Society for Peritoneal Dialysis (ISPD) Advisory Committee on Peritonitis Management in Pediatric Patients (2000) Consensus guidelines for the treatment of peritonitis in pediatric patients receiving peritoneal dialysis. Perit Dial Int 20(6):610–624PubMed Warady BA, Schaefer F, Holloway M, Alexander S, Kandert M, Piraino B, Salusky I, Tranaeus A, Divino J, Honda M, Mujais S, Verrina E, International Society for Peritoneal Dialysis (ISPD) Advisory Committee on Peritonitis Management in Pediatric Patients (2000) Consensus guidelines for the treatment of peritonitis in pediatric patients receiving peritoneal dialysis. Perit Dial Int 20(6):610–624PubMed
12.
go back to reference Piraino B, Bernardini J, Sorkin M (1986) The influence of peritoneal catheter exit-site infections on peritonitis, tunnel infections, and catheter loss in patients on continuous ambulatory peritoneal dialysis. Am J Kidney Dis 8(6):436–440PubMed Piraino B, Bernardini J, Sorkin M (1986) The influence of peritoneal catheter exit-site infections on peritonitis, tunnel infections, and catheter loss in patients on continuous ambulatory peritoneal dialysis. Am J Kidney Dis 8(6):436–440PubMed
13.
go back to reference Piraino B, Bernardini J, Sorkin M (1989) Catheter infections as a factor in the transfer of continuous ambulatory peritoneal dialysis patients to hemodialysis. Am J Kidney Dis 13(5):365–369PubMed Piraino B, Bernardini J, Sorkin M (1989) Catheter infections as a factor in the transfer of continuous ambulatory peritoneal dialysis patients to hemodialysis. Am J Kidney Dis 13(5):365–369PubMed
14.
go back to reference Thodis E, Passadakis P, Lyrantzopooulos N, Panagoutsos S, Vargemezis V, Oreopoulos D (2005) Peritoneal catheters and related infections. Int Urol Nephrol 37(2):379–393PubMedCrossRef Thodis E, Passadakis P, Lyrantzopooulos N, Panagoutsos S, Vargemezis V, Oreopoulos D (2005) Peritoneal catheters and related infections. Int Urol Nephrol 37(2):379–393PubMedCrossRef
15.
go back to reference Twardowski ZJ, Prowant BF, Nichols WK, Nolph KD, Khanna R (1992) Six-year experience with swan neck catheters. Perit Dial Int 12(4):384–389PubMed Twardowski ZJ, Prowant BF, Nichols WK, Nolph KD, Khanna R (1992) Six-year experience with swan neck catheters. Perit Dial Int 12(4):384–389PubMed
16.
go back to reference Vas SI (1994) Treatment of peritonitis. Perit Dial Int 14(Suppl 3):S49–S55PubMed Vas SI (1994) Treatment of peritonitis. Perit Dial Int 14(Suppl 3):S49–S55PubMed
17.
go back to reference Watson AR (1996) Chronic renal failure in childhood. Br J Hosp Med 55(6):329–331PubMed Watson AR (1996) Chronic renal failure in childhood. Br J Hosp Med 55(6):329–331PubMed
18.
go back to reference Warady BA, Hébert D, Sullivan EK, Alexander SR, Tejani A (1997) Renal transplantation, chronic dialysis, and chronic renal insufficiency in children and adolescents: the 1995 annual report of the North American Pediatric Renal Transplant Cooperative Study. Pediatr Nephrol 11(1):49–64PubMedCrossRef Warady BA, Hébert D, Sullivan EK, Alexander SR, Tejani A (1997) Renal transplantation, chronic dialysis, and chronic renal insufficiency in children and adolescents: the 1995 annual report of the North American Pediatric Renal Transplant Cooperative Study. Pediatr Nephrol 11(1):49–64PubMedCrossRef
19.
go back to reference Levy M, Balfe JW, Geary D, Fryer-Keene S, Bannatyne R (1990) Exit-site infection during continuous and cycling peritoneal dialysis in children. Perit Dial Int 10(1):31–35PubMed Levy M, Balfe JW, Geary D, Fryer-Keene S, Bannatyne R (1990) Exit-site infection during continuous and cycling peritoneal dialysis in children. Perit Dial Int 10(1):31–35PubMed
20.
go back to reference Neu AM, Kohaut EC, Warady BA (1995) Current approach to peritoneal access in North American children: a report of the Pediatric Peritoneal Dialysis Study Consortium. Adv Perit Dial 11:289–292PubMed Neu AM, Kohaut EC, Warady BA (1995) Current approach to peritoneal access in North American children: a report of the Pediatric Peritoneal Dialysis Study Consortium. Adv Perit Dial 11:289–292PubMed
21.
go back to reference Oreopoulos DG, Khanna R, Williams P, Vas SI (1982) Continuous ambulatory peritoneal dialysis: 1981. Nephron 30(4):293–303PubMedCrossRef Oreopoulos DG, Khanna R, Williams P, Vas SI (1982) Continuous ambulatory peritoneal dialysis: 1981. Nephron 30(4):293–303PubMedCrossRef
22.
go back to reference Lui SL, Li FK, Lo CY, Lo WK (2000) Simultaneous removal and reinsertion of Tenckhoff catheters for the treatment of refractory exit-site infection. Adv Perit Dial 16:195–197PubMed Lui SL, Li FK, Lo CY, Lo WK (2000) Simultaneous removal and reinsertion of Tenckhoff catheters for the treatment of refractory exit-site infection. Adv Perit Dial 16:195–197PubMed
23.
go back to reference Majkowski NL, Mendley SR (1997) Simultaneous removal and replacement of infected peritoneal dialysis catheters. Am J Kidney Dis 29(5):706–711PubMedCrossRef Majkowski NL, Mendley SR (1997) Simultaneous removal and replacement of infected peritoneal dialysis catheters. Am J Kidney Dis 29(5):706–711PubMedCrossRef
24.
go back to reference Yoshino A, Honda M, Ikeda M, Tsuchida S, Hataya H, Sakazume S, Tanaka Y, Shishido S, Nakai H (2004) Merit of the cuff-shaving procedure in children with chronic infection. Pediatr Nephrol 19(11):1267–1272PubMedCrossRef Yoshino A, Honda M, Ikeda M, Tsuchida S, Hataya H, Sakazume S, Tanaka Y, Shishido S, Nakai H (2004) Merit of the cuff-shaving procedure in children with chronic infection. Pediatr Nephrol 19(11):1267–1272PubMedCrossRef
25.
go back to reference Lewis MA, Smith T, Postlethwaite RJ, Webb NJ (1997) A comparison of double-cuffed with single-cuffed Tenckhoff catheters in the prevention of infection in pediatric patients. Adv Perit Dial 13:274–276PubMed Lewis MA, Smith T, Postlethwaite RJ, Webb NJ (1997) A comparison of double-cuffed with single-cuffed Tenckhoff catheters in the prevention of infection in pediatric patients. Adv Perit Dial 13:274–276PubMed
26.
go back to reference Schröder CH, Severijnen RS, de Jong MC, Monnens LA (1993) Chronic tunnel infections in children: removal and replacement of the continuous ambulatory peritoneal dialysis catheter in a single operation. Perit Dial Int 13(3):198–200PubMed Schröder CH, Severijnen RS, de Jong MC, Monnens LA (1993) Chronic tunnel infections in children: removal and replacement of the continuous ambulatory peritoneal dialysis catheter in a single operation. Perit Dial Int 13(3):198–200PubMed
27.
go back to reference Holley JL, Bernardini J, Piraino B (1994) Infecting organism in continuos ambulatory peritoneal dialysis patients on the Y-set. Am J Kidney Dis 23:569–573PubMed Holley JL, Bernardini J, Piraino B (1994) Infecting organism in continuos ambulatory peritoneal dialysis patients on the Y-set. Am J Kidney Dis 23:569–573PubMed
28.
go back to reference Piraino B (1996) Exit-site care. Perit Dial Int 16(Suppl 1):336–339 Piraino B (1996) Exit-site care. Perit Dial Int 16(Suppl 1):336–339
29.
go back to reference Macchini F, Valadè A, Ardissino G, Testa S, Edefonti A, Torricelli M, Luzzani S (2006) Chronic peritoneal dialysis in children: catheter related complications. a single centre experience. Pediatr Surg Int 22(6):524–528PubMedCrossRef Macchini F, Valadè A, Ardissino G, Testa S, Edefonti A, Torricelli M, Luzzani S (2006) Chronic peritoneal dialysis in children: catheter related complications. a single centre experience. Pediatr Surg Int 22(6):524–528PubMedCrossRef
Metadata
Title
Conservative surgical management of catheter infections in children on peritoneal dialysis
Authors
Francesco Macchini
Sara Testa
Alberto Valadè
Maurizio Torricelli
Ernesto Leva
Gianluigi Ardissino
Alberto Edefonti
Publication date
01-08-2009
Publisher
Springer-Verlag
Published in
Pediatric Surgery International / Issue 8/2009
Print ISSN: 0179-0358
Electronic ISSN: 1437-9813
DOI
https://doi.org/10.1007/s00383-009-2412-0

Other articles of this Issue 8/2009

Pediatric Surgery International 8/2009 Go to the issue