Skip to main content
Top
Published in: Pediatric Surgery International 8/2009

Open Access 01-08-2009 | Original Article

Anterior fundoplication at the time of congenital diaphragmatic hernia repair

Authors: Yigit S. Guner, Steven Elliott, Clifford C. Marr, Stephen K. Greenholz

Published in: Pediatric Surgery International | Issue 8/2009

Login to get access

Abstract

Purpose

The loss of normal anatomic barriers in neonates with congenital diaphragmatic hernia (CDH) can predispose children to gastroesophageal reflux (GER). In an attempt to improve post-operative feeding, we have added a modified anterior fundoplication to restore natural gastric and esophageal positioning.

Methods

The institutional review board of both participating centers approved this study. Between 1997 and 2008, 13 neonates with high-risk anatomy underwent repair of CDH combined with an anterior fundoplication (Boix-Ochoa). The anatomic indications for concomitant fundoplication were absence of an intra-abdominal esophagus, an obtuse angle of His, and a small, vertically oriented stomach.

Results

Ten patients survived to discharge and eight were on full oral nourishment. One required partial gastrostomy feedings for an improving oral aversion and quickly progressed to full oral feedings. One patient with chromosomal anomalies and swallowing dysfunction remained on long-term bolus gastrostomy feedings. Two with progressive symptoms of GER and failure to thrive required conversion to a 360° wrap after 18 months of medical management. This was performed in conjunction with a planned, staged muscle flap reconstruction in one patient. There were no complications related to the fundoplication.

Conclusion

Anatomic predictors of severe GER can be efficiently countered at the time of CDH repair. A modified fundoplication should be considered in the operative management of high-risk infants.
Literature
1.
go back to reference Stolar CJ, Levy JP, Dillon PW, Reyes C, Belamarich P, Berdon WE (1990) Anatomic and functional abnormalities of the esophagus in infants surviving congenital diaphragmatic hernia. Am J Surg 159:204–207PubMedCrossRef Stolar CJ, Levy JP, Dillon PW, Reyes C, Belamarich P, Berdon WE (1990) Anatomic and functional abnormalities of the esophagus in infants surviving congenital diaphragmatic hernia. Am J Surg 159:204–207PubMedCrossRef
2.
go back to reference Muratore CS, Utter S, Jaksic T, Lund DP, Wilson JM (2001) Nutritional morbidity in survivors of congenital diaphragmatic hernia. J Pediatr Surg 36:1171–1176PubMedCrossRef Muratore CS, Utter S, Jaksic T, Lund DP, Wilson JM (2001) Nutritional morbidity in survivors of congenital diaphragmatic hernia. J Pediatr Surg 36:1171–1176PubMedCrossRef
3.
go back to reference Koot VC, Bergmeijer JH, Bos AP, Molenaar JC (1993) Incidence and management of gastroesophageal reflux after repair of congenital diaphragmatic hernia. J Pediatr Surg 28:48–52PubMedCrossRef Koot VC, Bergmeijer JH, Bos AP, Molenaar JC (1993) Incidence and management of gastroesophageal reflux after repair of congenital diaphragmatic hernia. J Pediatr Surg 28:48–52PubMedCrossRef
4.
go back to reference Nagaya M, Akatsuka H, Kato J (1994) Gastroesophageal reflux occurring after repair of congenital diaphragmatic hernia. J Pediatr Surg 29:1447–1451PubMedCrossRef Nagaya M, Akatsuka H, Kato J (1994) Gastroesophageal reflux occurring after repair of congenital diaphragmatic hernia. J Pediatr Surg 29:1447–1451PubMedCrossRef
5.
go back to reference Su W, Berry M, Puligandla PS, Aspirot A, Flageole H, Laberge JM (2007) Predictors of gastroesophageal reflux in neonates with congenital diaphragmatic hernia. J Pediatr Surg 42:1639–1643PubMedCrossRef Su W, Berry M, Puligandla PS, Aspirot A, Flageole H, Laberge JM (2007) Predictors of gastroesophageal reflux in neonates with congenital diaphragmatic hernia. J Pediatr Surg 42:1639–1643PubMedCrossRef
6.
go back to reference D’Agostino JA, Bernbaum JC, Gerdes M et al (1995) Outcome for infants with congenital diaphragmatic hernia requiring extracorporeal membrane oxygenation: the first year. J Pediatr Surg 30:10–15PubMedCrossRef D’Agostino JA, Bernbaum JC, Gerdes M et al (1995) Outcome for infants with congenital diaphragmatic hernia requiring extracorporeal membrane oxygenation: the first year. J Pediatr Surg 30:10–15PubMedCrossRef
7.
go back to reference Boix-Ochoa J (1986) The physiologic approach to the management of gastric esophageal reflux. J Pediatr Surg 21:1032–1039PubMedCrossRef Boix-Ochoa J (1986) The physiologic approach to the management of gastric esophageal reflux. J Pediatr Surg 21:1032–1039PubMedCrossRef
8.
go back to reference Boix-Ochoa J, Rowe M (1998) Gastroesophageal reflux. Mosby-Year Book, St Louis Boix-Ochoa J, Rowe M (1998) Gastroesophageal reflux. Mosby-Year Book, St Louis
9.
go back to reference Boix-Ochoa J, Casasa Carbo JM (1977) Pathology of the cardio-hiatal sector. An Esp Pediatr 10:597–604PubMed Boix-Ochoa J, Casasa Carbo JM (1977) Pathology of the cardio-hiatal sector. An Esp Pediatr 10:597–604PubMed
10.
go back to reference Bardaji CB-OJ (1986) Contribution of the His angle to the gastroesophageal antireflux mechanisms. Pediatr Surg Int 1:172–176CrossRef Bardaji CB-OJ (1986) Contribution of the His angle to the gastroesophageal antireflux mechanisms. Pediatr Surg Int 1:172–176CrossRef
11.
go back to reference Subramaniam R, Dickson AP (2000) Long-term outcome of Boix-Ochoa and Nissen fundoplication in normal and neurologically impaired children. J Pediatr Surg 35:1214–1216PubMedCrossRef Subramaniam R, Dickson AP (2000) Long-term outcome of Boix-Ochoa and Nissen fundoplication in normal and neurologically impaired children. J Pediatr Surg 35:1214–1216PubMedCrossRef
12.
go back to reference Hernandez-Orgaz A, Lopez-Alonso M (2004) Surgical treatment of the GER with Boix-Ochoa technique: long-term results. Cir Pediatr 17:122–124PubMed Hernandez-Orgaz A, Lopez-Alonso M (2004) Surgical treatment of the GER with Boix-Ochoa technique: long-term results. Cir Pediatr 17:122–124PubMed
13.
go back to reference Numanoglu A, Millar AJ, Brown RA, Rode H (2005) Gastroesophageal reflux strictures in children, management and outcome. Pediatr Surg Int 21:631–634PubMedCrossRef Numanoglu A, Millar AJ, Brown RA, Rode H (2005) Gastroesophageal reflux strictures in children, management and outcome. Pediatr Surg Int 21:631–634PubMedCrossRef
14.
go back to reference Briganti V, Oriolo L, Calisti A (2003) Reflux strictures of the oesophagus in children: personal experience with preoperative dilatation followed by anterior funduplication. Pediatr Surg Int 19:544–547PubMedCrossRef Briganti V, Oriolo L, Calisti A (2003) Reflux strictures of the oesophagus in children: personal experience with preoperative dilatation followed by anterior funduplication. Pediatr Surg Int 19:544–547PubMedCrossRef
15.
go back to reference Greenholz SK, Hall R, Lilly JR (1989) The Boix-Ochoa antireflux operation in infants with small stomachs. Surg Gynecol Obstet 168:357–358PubMed Greenholz SK, Hall R, Lilly JR (1989) The Boix-Ochoa antireflux operation in infants with small stomachs. Surg Gynecol Obstet 168:357–358PubMed
16.
go back to reference Lee SL, Poulos ND, Greenholz SK (2002) Staged reconstruction of large congenital diaphragmatic defects with synthetic patch followed by reverse latissimus dorsi muscle. J Pediatr Surg 37:367–370PubMedCrossRef Lee SL, Poulos ND, Greenholz SK (2002) Staged reconstruction of large congenital diaphragmatic defects with synthetic patch followed by reverse latissimus dorsi muscle. J Pediatr Surg 37:367–370PubMedCrossRef
17.
go back to reference Kieffer J, Sapin E, Berg A, Beaudoin S, Bargy F, Helardot PG (1995) Gastroesophageal reflux after repair of congenital diaphragmatic hernia. J Pediatr Surg 30:1330–1333PubMedCrossRef Kieffer J, Sapin E, Berg A, Beaudoin S, Bargy F, Helardot PG (1995) Gastroesophageal reflux after repair of congenital diaphragmatic hernia. J Pediatr Surg 30:1330–1333PubMedCrossRef
18.
go back to reference Diamond IR, Mah K, Kim PC, Bohn D, Gerstle JT, Wales PW (2007) Predicting the need for fundoplication at the time of congenital diaphragmatic hernia repair. J Pediatr Surg 42:1066–1070PubMedCrossRef Diamond IR, Mah K, Kim PC, Bohn D, Gerstle JT, Wales PW (2007) Predicting the need for fundoplication at the time of congenital diaphragmatic hernia repair. J Pediatr Surg 42:1066–1070PubMedCrossRef
19.
go back to reference Fasching G, Huber A, Uray E, Sorantin E, Lindbichler F, Mayr J (2000) Gastroesophageal reflux and diaphragmatic motility after repair of congenital diaphragmatic hernia. Eur J Pediatr Surg 10:360–364PubMed Fasching G, Huber A, Uray E, Sorantin E, Lindbichler F, Mayr J (2000) Gastroesophageal reflux and diaphragmatic motility after repair of congenital diaphragmatic hernia. Eur J Pediatr Surg 10:360–364PubMed
20.
go back to reference Kamiyama M, Kawahara H, Okuyama H et al (2002) Gastroesophageal reflux after repair of congenital diaphragmatic hernia. J Pediatr Surg 37:1681–1684PubMedCrossRef Kamiyama M, Kawahara H, Okuyama H et al (2002) Gastroesophageal reflux after repair of congenital diaphragmatic hernia. J Pediatr Surg 37:1681–1684PubMedCrossRef
21.
go back to reference DeMeester TR, Wernly JA, Bryant GH, Little AG, Skinner DB (1979) Clinical and in vitro analysis of determinants of gastroesophageal competence: a study of the principles of antireflux surgery. Am J Surg 137:39–46PubMedCrossRef DeMeester TR, Wernly JA, Bryant GH, Little AG, Skinner DB (1979) Clinical and in vitro analysis of determinants of gastroesophageal competence: a study of the principles of antireflux surgery. Am J Surg 137:39–46PubMedCrossRef
22.
go back to reference Bonavina L, Evander A, DeMeester TR et al (1986) Length of the distal esophageal sphincter and competency of the cardia. Am J Surg 151:25–34PubMedCrossRef Bonavina L, Evander A, DeMeester TR et al (1986) Length of the distal esophageal sphincter and competency of the cardia. Am J Surg 151:25–34PubMedCrossRef
23.
go back to reference Robie DK, Pearl RH (1991) Modified Nissen fundoplication: improved results in high-risk children. J Pediatr Surg 26:1268–1272PubMedCrossRef Robie DK, Pearl RH (1991) Modified Nissen fundoplication: improved results in high-risk children. J Pediatr Surg 26:1268–1272PubMedCrossRef
24.
go back to reference Thor KB, Hill LD, Mercer DD, Kozarek RD (1987) Reappraisal of the flap valve mechanism in the gastroesophageal junction. a study of a new valvuloplasty procedure in cadavers. Acta Chir Scand 153:25–28PubMed Thor KB, Hill LD, Mercer DD, Kozarek RD (1987) Reappraisal of the flap valve mechanism in the gastroesophageal junction. a study of a new valvuloplasty procedure in cadavers. Acta Chir Scand 153:25–28PubMed
Metadata
Title
Anterior fundoplication at the time of congenital diaphragmatic hernia repair
Authors
Yigit S. Guner
Steven Elliott
Clifford C. Marr
Stephen K. Greenholz
Publication date
01-08-2009
Publisher
Springer-Verlag
Published in
Pediatric Surgery International / Issue 8/2009
Print ISSN: 0179-0358
Electronic ISSN: 1437-9813
DOI
https://doi.org/10.1007/s00383-009-2411-1

Other articles of this Issue 8/2009

Pediatric Surgery International 8/2009 Go to the issue