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Published in: Child's Nervous System 9/2019

01-09-2019 | Antibiotic | Focus Session

Management and prevention of cranioplasty infections

Authors: Paolo Frassanito, Flavia Fraschetti, Federico Bianchi, Francesca Giovannenze, Massimo Caldarelli, Giancarlo Scoppettuolo

Published in: Child's Nervous System | Issue 9/2019

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Abstract

Background

Infection may complicate the outcome of cranial repair with significant additional morbidity, related to hospitalization, surgery and long antibiotic therapy, that may become even dramatic in case of multi-resistant germs and in particular in the paediatric population. Additionally, the economic costs for the health system are obvious. Moreover, surgical decisions concerning the timing of cranioplasty and choice of the material may be strongly affected by the risk of infection. Despite, management and prevention of cranioplasty infections are not systematically treated through the literature so far.

Methods

We reviewed pertinent literature dealing with cranioplasty infection starting from the diagnosis to treatment options, namely conservative versus surgical ones. Our institutional bundle, specific to the paediatric population, is also presented. This approach aims to significantly reduce the risk of infection in first-line cranioplasty and redo cranioplasty after previous infection.

Conclusions

A thorough knowledge and understanding of risk factors may lead to surgical strategies and bundles, aiming to reduce infectious complications of cranioplasty. Finally, innovation in materials used for cranial repair should also aim to enhance the antimicrobial properties of these inert materials.
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Metadata
Title
Management and prevention of cranioplasty infections
Authors
Paolo Frassanito
Flavia Fraschetti
Federico Bianchi
Francesca Giovannenze
Massimo Caldarelli
Giancarlo Scoppettuolo
Publication date
01-09-2019
Publisher
Springer Berlin Heidelberg
Keyword
Antibiotic
Published in
Child's Nervous System / Issue 9/2019
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI
https://doi.org/10.1007/s00381-019-04251-8

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