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Published in: Child's Nervous System 12/2018

01-12-2018 | Review Paper

Clinico-radiological approach to cerebral hemiatrophy

Authors: Ai Peng Tan, Yen Ling Jocelyn Wong, Bingyuan Jeremy Lin, Hsiang Rong Clement Yong, Kshitij Mankad

Published in: Child's Nervous System | Issue 12/2018

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Abstract

Introduction

Cerebral hemiatrophy is an uncommon neuroimaging finding of diverse etiologies, conventionally classified into two broad categories: congenital and acquired. The authors propose an alternative pragmatic clinical approach to cerebral hemiatrophy, classifying its diverse etiologies into a single event insult such as an in utero stroke, or a progressive disorder from an inflammatory or neoplastic process, the latter of which needs urgent intervention and will be the focus of our review paper. Illustrative cases will also be presented to facilitate the understanding of the discussed disorders.

Conclusion

A systematic approach, linking both clinical and neuroimaging features, is important to facilitate the diagnostic workup of cerebral hemiatrophy. This may potentially help avoid large-scale investigations. Determining the underlying aetiology of cerebral hemiatrophy may impact treatment and prognostication as some conditions such as Rasmussen encephalitis and Parry-Romberg syndrome may benefit from timely implementation of immunomodulatory therapy.
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Metadata
Title
Clinico-radiological approach to cerebral hemiatrophy
Authors
Ai Peng Tan
Yen Ling Jocelyn Wong
Bingyuan Jeremy Lin
Hsiang Rong Clement Yong
Kshitij Mankad
Publication date
01-12-2018
Publisher
Springer Berlin Heidelberg
Published in
Child's Nervous System / Issue 12/2018
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI
https://doi.org/10.1007/s00381-018-3934-3

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