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Child's Nervous System
Published in: Child's Nervous System 12/2016

01-12-2016 | Case Report

Ultra early recurrence in giant congenital malignant rhabdoid tumor of spine

Authors: Navneet Singla, Ankur Kapoor, Debajyoti Chatterjee, B. D. Radotra

Published in: Child's Nervous System | Issue 12/2016

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Abstract

Background

Malignant rhabdoid tumor (MRT) is an aggressive tumor of infancy and childhood that rarely presents as a primary spinal or spinal cord tumor. There are only three reported cases of spinal MRT in infants.

Objective

We present a similar case in a 3-month male child who developed ultra-early recurrence, 4 weeks after complete excision. The diagnosis was confirmed by immunohistochemistry showing inactivation of the INI1 gene.

Result

Despite surgical excision and adjuvant chemoradiotherapy, these tumors have a progressive course and recurrence is a common phenomenon.

Conclusion

We believe that MRT must be considered in the differential diagnosis of the intra/paraspinal masses, especially in the infants.
Literature
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Bourdeaut F, Fréneaux P, Thuille B, Bergeron C, Laurence V, Brugières L (2008) Extra-renal non-cerebral rhabdoid tumours. Pediatr Blood Cancer 51(3):363–368CrossRefPubMed
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Dhir A, Tekautz T, Recinos V, Murphy E, Prayson RA, Ruggieri P (2015) Lumbar spinal atypical teratoid rhabdoid tumor. J Clin Neurosci 22(12):1988–1989CrossRefPubMed
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Howlett DC, King AP, Jarosz JM, Stewart RA, ST A-S, Bingham JB (1997) Imaging and pathological features of primary malignant rhabdoid tumours of the brain and spine. Neuroradiology 39:719–723CrossRefPubMed
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Louis DN, Ohgaki H, Wiestler OD, Cavenee WK (eds) (2007) WHO classification of tumours of the central nervous system. International Agency for Research on Cancer (IARC), Lyon
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Burger PC, IT Y, Tihan T, Friedman HS, Strother DR, Kepner JL, Duffner PK, Kun LE, Perlman EJ (1998) Atypical teratoid/rhabdoid tumor of the central nervous system: a highly malignant tumor of infancy and childhood frequently mistaken for medulloblastoma: a pediatric oncology group study. Am J Surg Pathol 22(9):1083–1092CrossRefPubMed
Metadata
Title
Ultra early recurrence in giant congenital malignant rhabdoid tumor of spine
Authors
Navneet Singla
Ankur Kapoor
Debajyoti Chatterjee
B. D. Radotra
Publication date
01-12-2016
Publisher
Springer Berlin Heidelberg
Published in
Child's Nervous System / Issue 12/2016
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI
https://doi.org/10.1007/s00381-016-3178-z

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