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01-05-2016 | Case Report

Pseudotumoral hemicerebellitis as a mimicker of Lhermitte-Duclos disease in children: does neuroimaging help to differentiate them?

Authors: Thangamadhan Bosemani, Maja Steinlin, Sandra P. Toelle, Jürgen Beck, Eugen Boltshauser, Thierry A. G. M. Huisman, Andrea Poretti

Published in: Child's Nervous System | Issue 5/2016

Abstract

The clinical presentation and neuroimaging findings of children with pseudotumoral hemicerebellitis (PTHC) and Lhermitte-Duclos disease (LDD) may be very similar. The differentiation between these entities, however, is important because their management and prognosis are different. We report on three children with PTHC. For all three children, in the acute situation, the differentiation between PTHC and LDD was challenging. A review of the literature shows that a detailed evaluation of conventional and neuroimaging data may help to differentiate between these two entities. A striated folial pattern, brainstem involvement, and prominent veins surrounding the thickened cerebellar foliae on susceptibility weighted imaging favor LDD, while post-contrast enhancement and an increased choline peak on ¹H-Magnetic resonance spectroscopy suggest PTHC.

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Title: Pseudotumoral hemicerebellitis as a mimicker of Lhermitte-Duclos disease in children: does neuroimaging help to differentiate them?
Authors: Thangamadhan Bosemani
Maja Steinlin
Sandra P. Toelle
Jürgen Beck
Eugen Boltshauser
Thierry A. G. M. Huisman
Andrea Poretti
Publication date: 01-05-2016
Publisher: Springer Berlin Heidelberg
Published in: Child's Nervous System / Issue 5/2016
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI: https://doi.org/10.1007/s00381-015-2977-y

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Pseudotumoral hemicerebellitis as a mimicker of Lhermitte-Duclos disease in children: does neuroimaging help to differentiate them?

Abstract

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