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Published in: Child's Nervous System 4/2016

01-04-2016 | Case Report

VP-shunt dysfunction caused by malaria CNS infection

Authors: Michael Karl Fehrenbach, Matthias Bernhard, Manuela Siekmeyer, Norman Lippmann, Wieland Kiess, Ulf Nestler, Jürgen Meixensberger, Matthias Preuss

Published in: Child's Nervous System | Issue 4/2016

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Abstract

Introduction

Malaria is a widespread mosquito-borne infectious disease with over 300 million cases and roughly 900 thousand deaths in 2013. Cerebral involvement of malaria causes 50 % of all infection-associated deaths, especially in children below the age of 5 years. Hydrocephalus is a medical condition with abnormal accumulation of cerebrospinal fluid in physiological cavities and ventricles. Standard treatment is the implantation of a cerebrospinal fluid shunt device. A common problem associated with shunt treatment especially in pediatric patients is infection and consecutive shunt dysfunction caused by bacteriae or high protein levels clogging the valve. In these cases, Staphylococcus aureus and Staphylococcus epidermidis are predominantly found in CSF cultures.

Case Presentation

We present a case of a 2-year old boy from Saudi Arabia with a ventriculoperitoneal (VP)-shunt-dependent congenital hydrocephalus who suffered from cerebral malaria and developed consecutive shunt failure.

Conclusion

To the best of our knowledge, shunt failure caused by malaria CNS infection with Plasmodium falciparum has not yet been reported in the literature and should be considered as a rare cause of VP-shunt failure in patients with atypical VP-shunt infections living in or traveling from endemic areas.
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Metadata
Title
VP-shunt dysfunction caused by malaria CNS infection
Authors
Michael Karl Fehrenbach
Matthias Bernhard
Manuela Siekmeyer
Norman Lippmann
Wieland Kiess
Ulf Nestler
Jürgen Meixensberger
Matthias Preuss
Publication date
01-04-2016
Publisher
Springer Berlin Heidelberg
Published in
Child's Nervous System / Issue 4/2016
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI
https://doi.org/10.1007/s00381-015-2912-2

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