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Child's Nervous System
Published in: Child's Nervous System 6/2014

01-06-2014 | Review Paper

Skull base embryology: a multidisciplinary review

Authors: Antonio Di Ieva, Emiliano Bruner, Thomas Haider, Luigi F. Rodella, John M. Lee, Michael D. Cusimano, Manfred Tschabitscher

Published in: Child's Nervous System | Issue 6/2014

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Abstract

Introduction

The skull base represents a central and complex bone structure of the skull and forms the floor of the cranial cavity on which the brain lies. Anatomical knowledge of this particular region is important for understanding several pathologic conditions as well as for planning surgical procedures. Embryology of the cranial base is of great interest due to its pronounced impact on the development of adjacent regions including the brain, neck, and craniofacial skeleton.

Materials and methods

Information from human and comparative anatomy, anthropology, embryology, surgery, and computed modelling was integrated to provide a perspective to interpret skull base formation and variability within the cranial functional and structural system.

Results and conclusions

The skull base undergoes an elaborate sequence of development stages and represents a key player in skull, face and brain development. Furthering our holistic understanding of the embryology of the skull base promises to expand our knowledge and enhance our ability to treat associated anomalies.
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Metadata
Title
Skull base embryology: a multidisciplinary review
Authors
Antonio Di Ieva
Emiliano Bruner
Thomas Haider
Luigi F. Rodella
John M. Lee
Michael D. Cusimano
Manfred Tschabitscher
Publication date
01-06-2014
Publisher
Springer Berlin Heidelberg
Published in
Child's Nervous System / Issue 6/2014
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI
https://doi.org/10.1007/s00381-014-2411-x

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