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Child's Nervous System

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01-11-2012 | Case Report

Primary spinal epidural rhabdomyosarcoma: a case report and review of the literature

Authors: Mahmoud Reza Khalatbari, Hassan Jalaeikhoo, Mehrdokht Hamidi, Yashar Moharamzad

Published in: Child's Nervous System | Issue 11/2012

Abstract

Background

Primary intraspinal sarcomas are very rare in children. Rhabdomyosarcoma (RMS) is a highly aggressive and rapidly growing sarcoma with skeletal origin that occasionally appears in the spinal epidural space.

Method

We report a 13-year-old girl who presented with back pain, progressive paraparesis, and urinary retention. She had muscular weakness in her lower extremities and absent deep tendon reflex. An epidural dumbbell-shape mass at T11–T12 level was observed on MRI. The patient underwent T12 hemilaminectomy, partial T11 hemilaminectomy, and right facetectomy. A large, firm, dark-red vascular epidural tumor was found compressing the cord. The tumor which extended to intracanal and foraminal parts was removed completely.

Discussion

Histopathological examination revealed undifferentiated small round and oval tumoral cells. Immunohistochemical staining was positive for vimentin, desmin, and myogenin. The final diagnosis was alveolar RMS. She received radiotherapy and chemotherapy by vincristine, actinomycin-D, doxorubicin, and ifosfamide. The patient was in good condition with no tumor recurrence or metastasis at the 1-year follow-up.

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Title: Primary spinal epidural rhabdomyosarcoma: a case report and review of the literature
Authors: Mahmoud Reza Khalatbari
Hassan Jalaeikhoo
Mehrdokht Hamidi
Yashar Moharamzad
Publication date: 01-11-2012
Publisher: Springer-Verlag
Published in: Child's Nervous System / Issue 11/2012
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI: https://doi.org/10.1007/s00381-012-1822-9

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Primary spinal epidural rhabdomyosarcoma: a case report and review of the literature

Abstract

Background

Method

Discussion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Method

Discussion

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