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Published in: Child's Nervous System 2/2010

01-02-2010 | Focus Session

Intracerebral microdialysis in children

Authors: Constantinos Charalambides, Spyros Sgouros, Damianos Sakas

Published in: Child's Nervous System | Issue 2/2010

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Abstract

Introduction

Cerebral microdialysis is a relatively new, minimally invasive technique that permits sampling and analyzing the chemical constituents of the extracellular fluid. Although mainly used as a research tool, it is also used in the neurointensive care, in combination with other monitoring methods, in patients with severe traumatic brain injury and subarachnoid hemorrhage. Its main clinical utility is the identification of markers of ischemia and cell damage with the ultimate goal of preventing any secondary insults to the brain by instituting early appropriate treatment measures. With few exceptions, all the available data on intracerebral microdialysis in humans comes from studies performed in adults.

Objective

The purpose of this report is to provide a brief review of the intracerebral microdialysis studies performed in children.

Conclusion

Differences in trends of concentrations of structural and excitatory amino acids have been identified in children, in comparison to those observed in adults, the significance of which remains unknown at present.
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Metadata
Title
Intracerebral microdialysis in children
Authors
Constantinos Charalambides
Spyros Sgouros
Damianos Sakas
Publication date
01-02-2010
Publisher
Springer-Verlag
Published in
Child's Nervous System / Issue 2/2010
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI
https://doi.org/10.1007/s00381-009-1031-3

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