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Child's Nervous System
Published in: Child's Nervous System 4/2009

01-04-2009 | Review Paper

A review on the management of epilepsy associated with hypothalamic hamartomas

Authors: James L. Frazier, C. Rory Goodwin, Edward S. Ahn, George I. Jallo

Published in: Child's Nervous System | Issue 4/2009

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Abstract

Introduction

Hypothalamic hamartomas are rare congenital malformations located in the region of the tuber cinereum and third ventricle. Patients may be asymptomatic, but the usual presentation is gelastic seizures, precocious puberty, and/or developmental delay.

Clinical presentation

Without surgical intervention, the gelastic seizures, which are typically present in childhood, may progress to other seizure types, including generalized epilepsy, and are generally refractory to antiepileptic drugs.

Summary

This review will discuss the clinical and electrophysiologic aspects of these lesions, as well as treatment options, including surgery, endoscopy, and radiosurgery.
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Metadata
Title
A review on the management of epilepsy associated with hypothalamic hamartomas
Authors
James L. Frazier
C. Rory Goodwin
Edward S. Ahn
George I. Jallo
Publication date
01-04-2009
Publisher
Springer-Verlag
Published in
Child's Nervous System / Issue 4/2009
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI
https://doi.org/10.1007/s00381-008-0798-y

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