Top

Child's Nervous System

Published in:

01-04-2009 | Original Paper

Clinical characteristic of spinal vascular malformation in pediatric patients

Authors: Jianxin Du, Feng Ling, Ming Chen, Hongqi Zhang

Published in: Child's Nervous System | Issue 4/2009

Abstract

Objective

Seventy-two pediatric spinal vascular malformation cases were reviewed and the characteristics of their clinical symptoms, diagnoses, and therapies were analyzed.

Materials and methods

A thorough overview was compiled examining patient sex, age, location, history, development, treatment, clinical, and anatomical results.

Results

Spinal cord arteriovenous malformation was the most common (44.4%) subtype to be seen in these pediatric patients, while subdural perimedullary arteriovenous fistula (23.6%) was the second, followed by Cobb’s syndrome (13.9%) and intramedullary cavernous angioma (5.6%). No spinal dual arteriovenous fistulae were found in infants. The highest incidence was seen during the infant and adolescent periods. Sixty-nine cases were treated by surgeries, embolizations, or a combination of both, and 71.5% of them had improved.

Conclusions

Early diagnosis and treatment are required. Surgery and embolization, or a combination of the two, are the current candidates for treatment.

Frisbie JH (2002) Spinal cord lesions caused by arteriovenous malformation: clinical course and risk of cancer. J Spinal Cord Med 25(4):284–288PubMed

Anson JA, Spetzler RF (1992) Classification of spinal arteriovenous malformations and implications for treatment. BNI Q 8:2–8

Bao YH, Ling F (1997) Classification and therapeutic modalities of spinal vascular malformations in 80 patients. Neurosurgery 40:75–81CrossRefPubMed

Rodesch G, Hurth M, Alvarez H, Tadie M, Lasjaunias P (2002) Classification of spinal cord arteriovenous shunts: proposal for a reappraisal—the Bicêtre experience with 155 consecutive patients treated between 1981 and 1999. Neurosurgery 51:374–380CrossRefPubMed

Aminoff MJ, Logue V (1974) The prognosis of patients with spinal vascular malformations. Brain 97:211–218CrossRefPubMed

Grote EH, Voigt K (1999) Clinical syndromes, natural history and physiopathology of vascular lesions of the spinal cord. Neurosurg Clin North Am 10:17–45

Gilbertson JR, Miller GM, Goldman MS, Marsh WR (1995) Spinal dural arteriovenous fistulas: MR and myelographic findings. AJNR Am J Neuroradiol 16(10):2049–2057PubMed

Thron A, Caplan LR (2003) Vascular malformations and interventional neuroradiology of the spinal cord. In: Brandt T, Caplan LR, Dichgans J et al (eds) Neurological disorders: course and treatment. 2nd edn. Amsterdam, Academic, pp 517–528

Garcia-Monaco R, Taylor W et al (1995) Pial arteriovenous fistula in children as revealing manifestation of Rendu–Osler–Weber disease. Neuroradiology 37:60–64CrossRefPubMed

10.

Rodesch G, Pongpech S, Alvarez H, Zerah M, Hurth M, Sebire G, Lasjaunias P (1995) Spinal cord arteriovenous malformations in a pediatric population (children below 15 years of age): the place of endovascular management. Interv Neuroradiol 1:29–42

11.

Zhang H, Ling F et al (2002) Study on the embryo spinal vascular development and its possible guideline effects to the treatment of spinal vascular malformations. J Chinese Neurosurg 18(3):153–156

12.

Krings T, Lasjaunias P et al (2006) Spinal vascular malformation, diagnostic and therapeutic management. Clin Neuroradiol 16:217–227CrossRef

13.

Ling F (1993) Classifications and treatments of the spinal cord vascular malformations. J Chinese Surg 31(1):1

14.

Rodesch G, Lasjaunias P (2003) Spinal cord arteriovenous shunts: from imaging to management. Eur J Radiol 46:221–232CrossRefPubMed

15.

Bandhyopadhyay S, Sheth RD (1999) Acute spinal cord infarction: vascular steal in arteriovenous malformation. J Child Neurol 14:685–687CrossRef

16.

Kataoka H, Miyamoto S et al (2001) Venous congestion is a major cause of neurological deterioration in spinal arteriovenous malformations? Neurosurgery 48:1224–1230CrossRefPubMed

17.

Rodesch G, Pongpech S, Alvarez H, Zerah M, Hurth M, Sebire G, Lasjaunias P (1995) Spinal cord arteriovenous malformations in a pediatric population. Children below 15 years of age. The place of endovascular treatment. Interv Neuroradiol 1:29–42

18.

Cullen S, Alvarez H et al (2006) Spinal arteriovenous shunts presenting before 2 years of age: analysis of 13 cases. Childs Nerv Syst 22:1103–1110CrossRefPubMed

Title: Clinical characteristic of spinal vascular malformation in pediatric patients
Authors: Jianxin Du
Feng Ling
Ming Chen
Hongqi Zhang
Publication date: 01-04-2009
Publisher: Springer-Verlag
Published in: Child's Nervous System / Issue 4/2009
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI: https://doi.org/10.1007/s00381-008-0737-y

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Clinical characteristic of spinal vascular malformation in pediatric patients

Abstract

Objective

Materials and methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objective

Materials and methods

Results

Conclusions

Please log in to get access to this content

Other articles of this Issue 4/2009

Surgery for epilepsy in children with dysembryoplastic neuroepithelial tumor: clinical spectrum, seizure outcome, neuroradiology, and pathology

Endoscopic third ventriculostomy versus ventriculoperitoneal shunt in pediatric patients: a decision analysis

Intermediate grade meningeal melanocytoma of cervical spine

A review on the management of epilepsy associated with hypothalamic hamartomas

Proatlantal intersegmental artery: a review of normal and pathological features

Factors contributing improvement of syringomyelia and surgical outcome in type I Chiari malformation