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World Journal of Urology
Published in: World Journal of Urology 12/2019

Open Access 01-12-2019 | Topic Paper

Imaging modalities in synchronous oligometastatic prostate cancer

Authors: Jurgen J. Futterer, Cristian Surcel, Roderick van den Bergh, Hendrik Borgmann, Alberto Briganti, Giorgio Gandaglia, Alexander Kretschmer, Piet Ost, Prasanna Sooriakumaran, Derya Tilki, Massimo Valerio, Guillaume Ploussard, Pieter J. L. De Visschere, Igor Tsaur, the EAU-YAU Prostate Cancer Working Party

Published in: World Journal of Urology | Issue 12/2019

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Abstract

Purpose

Along with a number of other malignancies, the term “oligometastatic” prostate cancer has recently emerged. It represents an attempt to define a subtype of cancer with a limited metastatic load that might perform more favorably than a distinctly disseminated disease, or even one that may be managed in a potentially curative way. Since there is currently a knowledge gap of what imaging modalities should be utilized to classify patients as having this type of tumor, we aimed to shed light on the role of conventional and marker-based imaging in the setting of synchronous oligometastatic prostate cancer as well as summarize the available evidence for its clinical application.

Methods

A literature search on December 15th 2017 was conducted using the Pubmed database.

Results

Functional imaging techniques like 68Ga PSMA. 68Ga PSMA PET-CT has currently been shown the best detection rates for the assessment of nodal, bone and visceral metastases, especially for smaller lesions at low PSA levels.

Conclusions

Functional imaging helps detect low-burden disease metastatic patients. However, these imaging modalities are not available in every center and thus clinicians may be prone to prescribe systemic treatment rather than referring patients for cytoreductive treatments. We hope that the ongoing prospective trials will help guide clinicians in making a more personalized management of synchronous metastatic patients.
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Metadata
Title
Imaging modalities in synchronous oligometastatic prostate cancer
Authors
Jurgen J. Futterer
Cristian Surcel
Roderick van den Bergh
Hendrik Borgmann
Alberto Briganti
Giorgio Gandaglia
Alexander Kretschmer
Piet Ost
Prasanna Sooriakumaran
Derya Tilki
Massimo Valerio
Guillaume Ploussard
Pieter J. L. De Visschere
Igor Tsaur
the EAU-YAU Prostate Cancer Working Party
Publication date
01-12-2019
Publisher
Springer Berlin Heidelberg
Published in
World Journal of Urology / Issue 12/2019
Print ISSN: 0724-4983
Electronic ISSN: 1433-8726
DOI
https://doi.org/10.1007/s00345-018-2416-2

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