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Published in: World Journal of Urology 11/2015

Open Access 01-11-2015 | Invited Review

Multiparametric ultrasound in the detection of prostate cancer: a systematic review

Authors: Arnoud Postema, Massimo Mischi, Jean de la Rosette, Hessel Wijkstra

Published in: World Journal of Urology | Issue 11/2015

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Abstract

Purpose

To investigate the advances and clinical results of the different ultrasound modalities and the progress in combining them into multiparametric UltraSound (mpUS).

Methods

A systematic literature search on mpUS and the different ultrasound modalities included: greyscale ultrasound, computerized transrectal ultrasound, Doppler and power Doppler techniques, dynamic contrast-enhanced ultrasound and (shear wave) elastography.

Results

Limited research available on combining ultrasound modalities has presented improvement in diagnostic performance. The data of two studies suggest that even adding a lower performing ultrasound modality to a better performing modality using crude methods can already improve the sensitivity by 13–51 %. The different modalities detect different tumours. No study has tried to combine ultrasound modalities employing a system similar to the PIRADS system used for mpMRI or more advanced classifying algorithms.

Conclusion

Available evidence confirms that combining different ultrasound modalities significantly improves diagnostic performance.
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Metadata
Title
Multiparametric ultrasound in the detection of prostate cancer: a systematic review
Authors
Arnoud Postema
Massimo Mischi
Jean de la Rosette
Hessel Wijkstra
Publication date
01-11-2015
Publisher
Springer Berlin Heidelberg
Published in
World Journal of Urology / Issue 11/2015
Print ISSN: 0724-4983
Electronic ISSN: 1433-8726
DOI
https://doi.org/10.1007/s00345-015-1523-6

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