Open Access 01-11-2015 | Invited Review
Multiparametric ultrasound in the detection of prostate cancer: a systematic review
Published in: World Journal of Urology | Issue 11/2015
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Purpose
To investigate the advances and clinical results of the different ultrasound modalities and the progress in combining them into multiparametric UltraSound (mpUS).
Methods
A systematic literature search on mpUS and the different ultrasound modalities included: greyscale ultrasound, computerized transrectal ultrasound, Doppler and power Doppler techniques, dynamic contrast-enhanced ultrasound and (shear wave) elastography.
Results
Limited research available on combining ultrasound modalities has presented improvement in diagnostic performance. The data of two studies suggest that even adding a lower performing ultrasound modality to a better performing modality using crude methods can already improve the sensitivity by 13–51 %. The different modalities detect different tumours. No study has tried to combine ultrasound modalities employing a system similar to the PIRADS system used for mpMRI or more advanced classifying algorithms.
Conclusion
Available evidence confirms that combining different ultrasound modalities significantly improves diagnostic performance.