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Published in: World Journal of Urology 5/2013

01-10-2013 | Topic Paper

Epidemiological gender-specific aspects in urolithiasis

Authors: Christian Seitz, Harun Fajkovic

Published in: World Journal of Urology | Issue 5/2013

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Abstract

Purpose

The incidence of urolithiasis is worldwide increasing and contributes to a rising economic and health care burden. The objective of this review is to identify gender differences in urolithiasis epidemiology in Europe and the USA as well as gender-specific risk factors for urolithiasis.

Evidence acquisition

A systematic review of the present literature was performed including English journals without a time limit. The MeSH terms used were as follows: (“Sex Characteristics”[Mesh]) AND “Urolithiasis”[Mesh] or (“Epidemiology”[Mesh]) AND “Urolithiasis”[Mesh]. Additionally, reference search of retrieved papers identified additional references. The MEDLINE database was searched.

Evidence synthesis

The prevalence of urolithiasis is rising worldwide including both genders in different age groups. Especially women face an increase in prevalence in the USA. Overweight seems to be an important cause for this development. Additionally insulin resistance and hypertonia, conditions present in the metabolic syndrome complex, contribute to this phenomenon.

Conclusion

Stone prevalence across all age groups and both genders is increasing. Lifestyle changes along with increasing prevalence of obesity are key factors for this development. Female gender did significantly differ in the risk ratio of stone development in different variables including body mass index, hyperinsulinemia, and hypertension. It is important to inform the public on measures how to change lifestyle and dietary measures for preventing or lowering events of stone disease.
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Metadata
Title
Epidemiological gender-specific aspects in urolithiasis
Authors
Christian Seitz
Harun Fajkovic
Publication date
01-10-2013
Publisher
Springer Berlin Heidelberg
Published in
World Journal of Urology / Issue 5/2013
Print ISSN: 0724-4983
Electronic ISSN: 1433-8726
DOI
https://doi.org/10.1007/s00345-013-1140-1

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