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01-06-2013 | Original Article

Athermal nerve sparing robot-assisted radical prostatectomy: initial experience with microporous polysaccharide hemospheres as a topical hemostatic agent

Authors: Rafael Nunez-Nateras, Kimberly J. Hurd, Erin N. Ferrigni, Erik P. Castle, Paul E. Andrews, Mitchell R. Humphreys

Published in: World Journal of Urology | Issue 3/2013

Abstract

Purpose

Microporous polysaccharide hemospheres (MPH) are hemostatic beads engineered from plant starch to accelerate the natural clotting cascade. The purpose of this report is to detail our initial experience with MPH as a topical hemostatic agent during robot-assisted radical prostatectomy (RARP).

Methods

We examined a single surgeon series of 30 consecutive RARP’s dividing patients into MPH or non-MPH groups. The last ten procedures utilized the MPH, which were matched 1:2 to non-MPH procedures for comparison. Nerve-sparing procedures were performed when clinically indicated and all done athermally. All demographic data, length of operation, margin status, blood loss, change in hemoglobin, and need for blood transfusion were prospectively collected and analyzed.

Results

The baseline characteristics were the same. The post-operative decrease in hemoglobin was less in the MPH group (1.8 g/dL MPH group vs. 3.2 g/dL non-MPH). One patient in each group required a blood transfusion.

Conclusions

These preliminary findings support the role for MPH as a potential hemostatic agent during athermal nerve-sparing RARP.

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Title: Athermal nerve sparing robot-assisted radical prostatectomy: initial experience with microporous polysaccharide hemospheres as a topical hemostatic agent
Authors: Rafael Nunez-Nateras
Kimberly J. Hurd
Erin N. Ferrigni
Erik P. Castle
Paul E. Andrews
Mitchell R. Humphreys
Publication date: 01-06-2013
Publisher: Springer-Verlag
Published in: World Journal of Urology / Issue 3/2013
Print ISSN: 0724-4983
Electronic ISSN: 1433-8726
DOI: https://doi.org/10.1007/s00345-011-0815-8

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Athermal nerve sparing robot-assisted radical prostatectomy: initial experience with microporous polysaccharide hemospheres as a topical hemostatic agent

Abstract

Purpose

Methods

Results

Conclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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