Skip to main content
Top
Published in: World Journal of Urology 1/2012

01-02-2012 | Topic Paper

Advances in non-surgical treatments for urinary tract infections in children

Authors: Stephen Shei-Dei Yang, I-Ni Chiang, Chia-Da Lin, Shang-Jen Chang

Published in: World Journal of Urology | Issue 1/2012

Login to get access

Abstract

Objective

With growing antibiotics failure due to emerging resistance of bacteria, non-surgical management of pediatric UTI plays a more important role because of its non-invasive characteristics and little adverse effects.

Methods

We searched the Pubmed for management of UTI in children other than surgical correction and antibiotics using terms: risk factor, prepuce/phimosis, steroid cream/steroid, behavioral therapy, urotherapy, biofeedback/pelvic floor exercise, adrenergic antagonist, anticholinergics, diet/dietary, dysfunctional voiding/dysfunctional elimination syndrome, constipation, dietary, clean intermittent catheterization, probiotics/lactobacillus, cranberry, vitamin supplement, breastfeeding, breast milk, with infant/child/children/pediatrics/pediatrics and urinary tract infection.

Results

The proposed non-surgical management of pediatric UTI included behavioral modification (timed voiding and adequate fluids intake), topical steroid for phimosis, nutrient supplements (breast milk, cranberry, probiotics, and vitamin A), biofeedback training for dysfunctional voiding, anticholinergics for reducing intravesical pressure, alpha-blockers in dysfunctional voiding and neurogenic bladder, and intermittent catheterization for children with large PVR.

Conclusion

The published reports usually included small number of patients and were lacking of randomization and controlled group. Further well-designed studies are warranted to support the concepts of non-operative management for pediatric UTI.
Literature
1.
go back to reference Nuutinen M, Uhari M (2001) Recurrence and follow-up after urinary tract infection under the age of 1 year. Pediatr Nephrol 16(1):69–72PubMedCrossRef Nuutinen M, Uhari M (2001) Recurrence and follow-up after urinary tract infection under the age of 1 year. Pediatr Nephrol 16(1):69–72PubMedCrossRef
2.
go back to reference Hiraoka M, Tsukahara H, Ohshima Y, Mayumi M (2002) Meatus tightly covered by the prepuce is associated with urinary infection. Pediatr Int 44(6):658–662PubMedCrossRef Hiraoka M, Tsukahara H, Ohshima Y, Mayumi M (2002) Meatus tightly covered by the prepuce is associated with urinary infection. Pediatr Int 44(6):658–662PubMedCrossRef
3.
go back to reference Shim YH, Lee JW, Lee SJ (2008) The risk factors of recurrent urinary tract infection in infants with normal urinary systems. Pediatr Nephrol Shim YH, Lee JW, Lee SJ (2008) The risk factors of recurrent urinary tract infection in infants with normal urinary systems. Pediatr Nephrol
4.
go back to reference Singh-Grewal D, Macdessi J, Craig J (2005) Circumcision for the prevention of urinary tract infection in boys: a systematic review of randomised trials and observational studies. Arch Dis Child 90(8):853–858PubMedCrossRef Singh-Grewal D, Macdessi J, Craig J (2005) Circumcision for the prevention of urinary tract infection in boys: a systematic review of randomised trials and observational studies. Arch Dis Child 90(8):853–858PubMedCrossRef
5.
go back to reference Jorgensen ET, Svensson A (1993) The treatment of phimosis in boys, with a potent topical steroid (clobetasol propionate 0.05%) cream. Acta Derm Venereol 73(1):55–56PubMed Jorgensen ET, Svensson A (1993) The treatment of phimosis in boys, with a potent topical steroid (clobetasol propionate 0.05%) cream. Acta Derm Venereol 73(1):55–56PubMed
6.
go back to reference Golubovic Z, Milanovic D, Vukadinovic V, Rakic I, Perovic S (1996) The conservative treatment of phimosis in boys. Br J Urol 78(5):786–788PubMedCrossRef Golubovic Z, Milanovic D, Vukadinovic V, Rakic I, Perovic S (1996) The conservative treatment of phimosis in boys. Br J Urol 78(5):786–788PubMedCrossRef
7.
go back to reference Yang SS, Tsai YC, Wu CC, Liu SP, Wang CC (2005) Highly potent and moderately potent topical steroids are effective in treating phimosis: a prospective randomized study. J Urol 173(4):1361–1363PubMedCrossRef Yang SS, Tsai YC, Wu CC, Liu SP, Wang CC (2005) Highly potent and moderately potent topical steroids are effective in treating phimosis: a prospective randomized study. J Urol 173(4):1361–1363PubMedCrossRef
8.
go back to reference Lee JW, Cho SJ, Park EA, Lee SJ (2006) Topical hydrocortisone and physiotherapy for nonretractile physiologic phimosis in infants. Pediatr Nephrol 21(8):1127–1130PubMedCrossRef Lee JW, Cho SJ, Park EA, Lee SJ (2006) Topical hydrocortisone and physiotherapy for nonretractile physiologic phimosis in infants. Pediatr Nephrol 21(8):1127–1130PubMedCrossRef
9.
go back to reference Orsola A, Caffaratti J, Garat JM (2000) Conservative treatment of phimosis in children using a topical steroid. Urology 56(2):307–310PubMedCrossRef Orsola A, Caffaratti J, Garat JM (2000) Conservative treatment of phimosis in children using a topical steroid. Urology 56(2):307–310PubMedCrossRef
10.
go back to reference Stauffer CM, van der WB, Donadini R, Ramelli GP, Marchand S, Bianchetti MG (2004) Family history and behavioral abnormalities in girls with recurrent urinary tract infections: a controlled study. J Urol 171(4):1663–1665PubMedCrossRef Stauffer CM, van der WB, Donadini R, Ramelli GP, Marchand S, Bianchetti MG (2004) Family history and behavioral abnormalities in girls with recurrent urinary tract infections: a controlled study. J Urol 171(4):1663–1665PubMedCrossRef
11.
go back to reference Mazzola BL, von Vigier RO, Marchand S, Tonz M, Bianchetti MG (2003) Behavioral and functional abnormalities linked with recurrent urinary tract infections in girls. J Nephrol 16(1):133–138PubMed Mazzola BL, von Vigier RO, Marchand S, Tonz M, Bianchetti MG (2003) Behavioral and functional abnormalities linked with recurrent urinary tract infections in girls. J Nephrol 16(1):133–138PubMed
12.
go back to reference Shaikh N, Abedin S, Docimo SG (2005) Can ultrasonography or uroflowmetry predict which children with voiding dysfunction will have recurrent urinary tract infections? J Urol 174(4 Pt 2):1620–1622PubMedCrossRef Shaikh N, Abedin S, Docimo SG (2005) Can ultrasonography or uroflowmetry predict which children with voiding dysfunction will have recurrent urinary tract infections? J Urol 174(4 Pt 2):1620–1622PubMedCrossRef
13.
go back to reference Yang SS, Chang SJ (2008) The effects of bladder over distention on voiding function in kindergarteners. J Urol 180(5):2177–2182PubMedCrossRef Yang SS, Chang SJ (2008) The effects of bladder over distention on voiding function in kindergarteners. J Urol 180(5):2177–2182PubMedCrossRef
14.
go back to reference Wennergren HM, Oberg BE, Sandstedt P (1991) The importance of leg support for relaxation of the pelvic floor muscles. A surface electromyograph study in healthy girls. Scand J Urol Nephrol 25(3):205–213PubMedCrossRef Wennergren HM, Oberg BE, Sandstedt P (1991) The importance of leg support for relaxation of the pelvic floor muscles. A surface electromyograph study in healthy girls. Scand J Urol Nephrol 25(3):205–213PubMedCrossRef
15.
go back to reference Shaikh N, Abedin S, Docimo SG (2005) Can ultrasonography or uroflowmetry predict which children with voiding dysfunction will have recurrent urinary tract infections? J Urol 174(4 Pt 2):1620–1622PubMedCrossRef Shaikh N, Abedin S, Docimo SG (2005) Can ultrasonography or uroflowmetry predict which children with voiding dysfunction will have recurrent urinary tract infections? J Urol 174(4 Pt 2):1620–1622PubMedCrossRef
16.
go back to reference Hellstrom AL, Sillen U (2001) Early potty training advantageous in bladder dysfunction. Decreases the risk of urinary infection. Lakartidningen 98(28–29):3216–3219PubMed Hellstrom AL, Sillen U (2001) Early potty training advantageous in bladder dysfunction. Decreases the risk of urinary infection. Lakartidningen 98(28–29):3216–3219PubMed
17.
go back to reference Duong TH, Jansson UB, Holmdahl G, Sillen U, Hellstrom AL (2010) Development of bladder control in the first year of life in children who are potty trained early. J Pediatr Urol 6(5):501–505PubMedCrossRef Duong TH, Jansson UB, Holmdahl G, Sillen U, Hellstrom AL (2010) Development of bladder control in the first year of life in children who are potty trained early. J Pediatr Urol 6(5):501–505PubMedCrossRef
18.
go back to reference Jansson UB, Hanson M, Hanson E, Hellstrom AL, Sillen U (2000) Voiding pattern in healthy children 0 to 3 years old: a longitudinal study. J Urol 164(6):2050–2054PubMedCrossRef Jansson UB, Hanson M, Hanson E, Hellstrom AL, Sillen U (2000) Voiding pattern in healthy children 0 to 3 years old: a longitudinal study. J Urol 164(6):2050–2054PubMedCrossRef
19.
go back to reference Yang SS, Zhao LL, Chang SJ (2011) Early initiation of toilet training for urine was associated with early urinary continence and does not appear to be associated with bladder dysfunction. Neurourol Urodyn Yang SS, Zhao LL, Chang SJ (2011) Early initiation of toilet training for urine was associated with early urinary continence and does not appear to be associated with bladder dysfunction. Neurourol Urodyn
20.
go back to reference Joinson C, Heron J, Von GA, Butler U, Emond A, Golding J (2009) A prospective study of age at initiation of toilet training and subsequent daytime bladder control in school-age children. J Dev Behav Pediatr 30(5):385–393PubMedCrossRef Joinson C, Heron J, Von GA, Butler U, Emond A, Golding J (2009) A prospective study of age at initiation of toilet training and subsequent daytime bladder control in school-age children. J Dev Behav Pediatr 30(5):385–393PubMedCrossRef
21.
go back to reference Shortliffe LM (1995) The management of urinary tract infections in children without urinary tract abnormalities. Urol Clin North Am 22(1):67–73PubMed Shortliffe LM (1995) The management of urinary tract infections in children without urinary tract abnormalities. Urol Clin North Am 22(1):67–73PubMed
22.
go back to reference Koff SA, Wagner TT, Jayanthi VR (1998) The relationship among dysfunctional elimination syndromes, primary vesicoureteral reflux and urinary tract infections in children. J Urol 160(3 Pt 2):1019–1022PubMed Koff SA, Wagner TT, Jayanthi VR (1998) The relationship among dysfunctional elimination syndromes, primary vesicoureteral reflux and urinary tract infections in children. J Urol 160(3 Pt 2):1019–1022PubMed
23.
go back to reference Yang SS, Wang CC (2005) Outpatient biofeedback relaxation of the pelvic floor in treating pediatric dysfunctional voiding: a short-course program is effective. Urol Int 74(2):118–122CrossRef Yang SS, Wang CC (2005) Outpatient biofeedback relaxation of the pelvic floor in treating pediatric dysfunctional voiding: a short-course program is effective. Urol Int 74(2):118–122CrossRef
24.
go back to reference De PH, Hoebeke P, Renson C, Van LE, Raes A, Van HE et al (1998) Pelvic-floor therapy in girls with recurrent urinary tract infections and dysfunctional voiding. Br J Urol 81(Suppl 3):109–113 De PH, Hoebeke P, Renson C, Van LE, Raes A, Van HE et al (1998) Pelvic-floor therapy in girls with recurrent urinary tract infections and dysfunctional voiding. Br J Urol 81(Suppl 3):109–113
25.
go back to reference Herndon CD, DeCambre M, McKenna PH (2001) Changing concepts concerning the management of vesicoureteral reflux. J Urol 166(4):1439–1443PubMedCrossRef Herndon CD, DeCambre M, McKenna PH (2001) Changing concepts concerning the management of vesicoureteral reflux. J Urol 166(4):1439–1443PubMedCrossRef
26.
go back to reference Khen-Dunlop N, Van EA, Bouteiller C, Biserte J, Besson R (2006) Biofeedback therapy in the treatment of bladder overactivity, vesico-ureteral reflux and urinary tract infection. J Pediatr Urol 2(5):424–429PubMedCrossRef Khen-Dunlop N, Van EA, Bouteiller C, Biserte J, Besson R (2006) Biofeedback therapy in the treatment of bladder overactivity, vesico-ureteral reflux and urinary tract infection. J Pediatr Urol 2(5):424–429PubMedCrossRef
27.
go back to reference Herndon CD, Decambre M, McKenna PH (2001) Interactive computer games for treatment of pelvic floor dysfunction. J Urol 166(5):1893–1898PubMedCrossRef Herndon CD, Decambre M, McKenna PH (2001) Interactive computer games for treatment of pelvic floor dysfunction. J Urol 166(5):1893–1898PubMedCrossRef
28.
go back to reference Schlager TA, Dilks S, Trudell J, Whittam TS, Hendley JO (1995) Bacteriuria in children with neurogenic bladder treated with intermittent catheterization: natural history. J Pediatr 126(3):490–496PubMedCrossRef Schlager TA, Dilks S, Trudell J, Whittam TS, Hendley JO (1995) Bacteriuria in children with neurogenic bladder treated with intermittent catheterization: natural history. J Pediatr 126(3):490–496PubMedCrossRef
29.
go back to reference Moore KN, Fader M, Getliffe K (2007) Long-term bladder management by intermittent catheterisation in adults and children. Cochrane Database Syst Rev (4):CD006008 Moore KN, Fader M, Getliffe K (2007) Long-term bladder management by intermittent catheterisation in adults and children. Cochrane Database Syst Rev (4):CD006008
30.
go back to reference van den Berg MM, Benninga MA, Di LC (2006) Epidemiology of childhood constipation: a systematic review. Am J Gastroenterol 101(10):2401–2409PubMedCrossRef van den Berg MM, Benninga MA, Di LC (2006) Epidemiology of childhood constipation: a systematic review. Am J Gastroenterol 101(10):2401–2409PubMedCrossRef
31.
go back to reference Rasquin A, Di LC, Forbes D, Guiraldes E, Hyams JS, Staiano A et al (2006) Childhood functional gastrointestinal disorders: child/adolescent. Gastroenterology 130(5):1527–1537PubMedCrossRef Rasquin A, Di LC, Forbes D, Guiraldes E, Hyams JS, Staiano A et al (2006) Childhood functional gastrointestinal disorders: child/adolescent. Gastroenterology 130(5):1527–1537PubMedCrossRef
32.
go back to reference Franco I (2007) Overactive bladder in children. Part 1: pathophysiology. J Urol 178(3 Pt 1):761–768PubMedCrossRef Franco I (2007) Overactive bladder in children. Part 1: pathophysiology. J Urol 178(3 Pt 1):761–768PubMedCrossRef
33.
go back to reference Giramonti KM, Kogan BA, Agboola OO, Ribons L, Dangman B (2005) The association of constipation with childhood urinary tract infections. J Pediatr Urol 1(4):273–278PubMedCrossRef Giramonti KM, Kogan BA, Agboola OO, Ribons L, Dangman B (2005) The association of constipation with childhood urinary tract infections. J Pediatr Urol 1(4):273–278PubMedCrossRef
34.
go back to reference Romanczuk W, Korczawski R (1993) Chronic constipation: a cause of recurrent urinary tract infections. Turk J Pediatr 35(3):181–188PubMed Romanczuk W, Korczawski R (1993) Chronic constipation: a cause of recurrent urinary tract infections. Turk J Pediatr 35(3):181–188PubMed
35.
go back to reference Loening-Baucke V (1997) Urinary incontinence and urinary tract infection and their resolution with treatment of chronic constipation of childhood. Pediatrics 100(2 Pt 1):228–232PubMedCrossRef Loening-Baucke V (1997) Urinary incontinence and urinary tract infection and their resolution with treatment of chronic constipation of childhood. Pediatrics 100(2 Pt 1):228–232PubMedCrossRef
37.
go back to reference Goldblum RM, Schanler RJ, Garza C, Goldman AS (1989) Human milk feeding enhances the urinary excretion of immunologic factors in low birth weight infants. Pediatr Res 25(2):184–188PubMedCrossRef Goldblum RM, Schanler RJ, Garza C, Goldman AS (1989) Human milk feeding enhances the urinary excretion of immunologic factors in low birth weight infants. Pediatr Res 25(2):184–188PubMedCrossRef
38.
go back to reference Gothefors L, Olling S, Winberg J (1975) Breast feeding, biological properties of faecal E. coli strains. Acta Paediatr Scand 64(6):807–812PubMedCrossRef Gothefors L, Olling S, Winberg J (1975) Breast feeding, biological properties of faecal E. coli strains. Acta Paediatr Scand 64(6):807–812PubMedCrossRef
39.
go back to reference Marild S, Jodal U, Mangelus L (1989) Medical histories of children with acute pyelonephritis compared with controls. Pediatr Infect Dis J 8(8):511–515PubMedCrossRef Marild S, Jodal U, Mangelus L (1989) Medical histories of children with acute pyelonephritis compared with controls. Pediatr Infect Dis J 8(8):511–515PubMedCrossRef
40.
go back to reference Marild S, Hansson S, Jodal U, Oden A, Svedberg K (2004) Protective effect of breastfeeding against urinary tract infection. Acta Paediatr 93(2):164–168PubMedCrossRef Marild S, Hansson S, Jodal U, Oden A, Svedberg K (2004) Protective effect of breastfeeding against urinary tract infection. Acta Paediatr 93(2):164–168PubMedCrossRef
41.
go back to reference Levy I, Comarsca J, Davidovits M, Klinger G, Sirota L, Linder N (2009) Urinary tract infection in preterm infants: the protective role of breastfeeding. Pediatr Nephrol 24(3):527–531PubMedCrossRef Levy I, Comarsca J, Davidovits M, Klinger G, Sirota L, Linder N (2009) Urinary tract infection in preterm infants: the protective role of breastfeeding. Pediatr Nephrol 24(3):527–531PubMedCrossRef
42.
go back to reference Ladomenou F, Moschandreas J, Kafatos A, Tselentis Y, Galanakis E (2010) Protective effect of exclusive breastfeeding against infections during infancy: a prospective study. Arch Dis Child 95(12):1004–1008PubMedCrossRef Ladomenou F, Moschandreas J, Kafatos A, Tselentis Y, Galanakis E (2010) Protective effect of exclusive breastfeeding against infections during infancy: a prospective study. Arch Dis Child 95(12):1004–1008PubMedCrossRef
43.
go back to reference Jepson RG, Craig JC (2008) Cranberries for preventing urinary tract infections. Cochrane Database Syst Rev (1):CD001321 Jepson RG, Craig JC (2008) Cranberries for preventing urinary tract infections. Cochrane Database Syst Rev (1):CD001321
44.
go back to reference Di MP, Agniel R, David K, Templer C, Gaillard JL, Denys P et al (2006) Reduction of Escherichia coli adherence to uroepithelial bladder cells after consumption of cranberry juice: a double-blind randomized placebo-controlled cross-over trial. World J Urol 24(1):21–27CrossRef Di MP, Agniel R, David K, Templer C, Gaillard JL, Denys P et al (2006) Reduction of Escherichia coli adherence to uroepithelial bladder cells after consumption of cranberry juice: a double-blind randomized placebo-controlled cross-over trial. World J Urol 24(1):21–27CrossRef
45.
go back to reference Schlager TA, Anderson S, Trudell J, Hendley JO (1999) Effect of cranberry juice on bacteriuria in children with neurogenic bladder receiving intermittent catheterization. J Pediatr 135(6):698–702PubMedCrossRef Schlager TA, Anderson S, Trudell J, Hendley JO (1999) Effect of cranberry juice on bacteriuria in children with neurogenic bladder receiving intermittent catheterization. J Pediatr 135(6):698–702PubMedCrossRef
46.
go back to reference Foda MM, Middlebrook PF, Gatfield CT, Potvin G, Wells G, Schillinger JF (1995) Efficacy of cranberry in prevention of urinary tract infection in a susceptible pediatric population. Can J Urol 2(1):98–102PubMed Foda MM, Middlebrook PF, Gatfield CT, Potvin G, Wells G, Schillinger JF (1995) Efficacy of cranberry in prevention of urinary tract infection in a susceptible pediatric population. Can J Urol 2(1):98–102PubMed
47.
go back to reference Ferrara P, Romaniello L, Vitelli O, Gatto A, Serva M, Cataldi L (2009) Cranberry juice for the prevention of recurrent urinary tract infections: a randomized controlled trial in children. Scand J Urol Nephrol 43(5):369–372PubMedCrossRef Ferrara P, Romaniello L, Vitelli O, Gatto A, Serva M, Cataldi L (2009) Cranberry juice for the prevention of recurrent urinary tract infections: a randomized controlled trial in children. Scand J Urol Nephrol 43(5):369–372PubMedCrossRef
48.
go back to reference Nishizaki N, Someya T, Hirano D, Fujinaga S, Ohtomo Y, Shimizu T et al (2009) Can cranberry juice be a substitute for cefaclor prophylaxis in children with vesicoureteral reflux? Pediatr Int 51(3):433–434PubMedCrossRef Nishizaki N, Someya T, Hirano D, Fujinaga S, Ohtomo Y, Shimizu T et al (2009) Can cranberry juice be a substitute for cefaclor prophylaxis in children with vesicoureteral reflux? Pediatr Int 51(3):433–434PubMedCrossRef
49.
go back to reference Reid G (2002) The potential role of probiotics in pediatric urology. J Urol 168(4 Pt 1):1512–1517PubMed Reid G (2002) The potential role of probiotics in pediatric urology. J Urol 168(4 Pt 1):1512–1517PubMed
50.
go back to reference Dani C, Biadaioli R, Bertini G, Martelli E, Rubaltelli FF (2002) Probiotics feeding in prevention of urinary tract infection, bacterial sepsis and necrotizing enterocolitis in preterm infants. A prospective double-blind study. Biol Neonate 82(2):103–108PubMedCrossRef Dani C, Biadaioli R, Bertini G, Martelli E, Rubaltelli FF (2002) Probiotics feeding in prevention of urinary tract infection, bacterial sepsis and necrotizing enterocolitis in preterm infants. A prospective double-blind study. Biol Neonate 82(2):103–108PubMedCrossRef
51.
go back to reference Lee SJ, Shim YH, Cho SJ, Lee JW (2007) Probiotics prophylaxis in children with persistent primary vesicoureteral reflux. Pediatr Nephrol 22(9):1315–1320PubMedCrossRef Lee SJ, Shim YH, Cho SJ, Lee JW (2007) Probiotics prophylaxis in children with persistent primary vesicoureteral reflux. Pediatr Nephrol 22(9):1315–1320PubMedCrossRef
52.
go back to reference Land MH, Rouster-Stevens K, Woods CR, Cannon ML, Cnota J, Shetty AK (2005) Lactobacillus sepsis associated with probiotic therapy. Pediatrics 115(1):178–181PubMed Land MH, Rouster-Stevens K, Woods CR, Cannon ML, Cnota J, Shetty AK (2005) Lactobacillus sepsis associated with probiotic therapy. Pediatrics 115(1):178–181PubMed
53.
go back to reference Schaier M, Lehrke I, Schade K, Morath C, Shimizu F, Kawachi H et al (2001) Isotretinoin alleviates renal damage in rat chronic glomerulonephritis. Kidney Int 60(6):2222–2234PubMedCrossRef Schaier M, Lehrke I, Schade K, Morath C, Shimizu F, Kawachi H et al (2001) Isotretinoin alleviates renal damage in rat chronic glomerulonephritis. Kidney Int 60(6):2222–2234PubMedCrossRef
54.
go back to reference Ayazi P, Moshiri SA, Mahyar A, Moradi M (2011) The effect of vitamin A on renal damage following acute pyelonephritis in children. Eur J Pediatr 170(3):347–350PubMedCrossRef Ayazi P, Moshiri SA, Mahyar A, Moradi M (2011) The effect of vitamin A on renal damage following acute pyelonephritis in children. Eur J Pediatr 170(3):347–350PubMedCrossRef
55.
go back to reference Yilmaz A, Bahat E, Yilmaz GG, Hasanoglu A, Akman S, Guven AG (2007) Adjuvant effect of vitamin A on recurrent lower urinary tract infections. Pediatr Int 49(3):310–313PubMedCrossRef Yilmaz A, Bahat E, Yilmaz GG, Hasanoglu A, Akman S, Guven AG (2007) Adjuvant effect of vitamin A on recurrent lower urinary tract infections. Pediatr Int 49(3):310–313PubMedCrossRef
56.
go back to reference Yang SS, Wang CC, Chen YT (2003) Effectiveness of alpha1-adrenergic blockers in boys with low urinary flow rate and urinary incontinence. J Formos Med Assoc 102(8):551–555PubMed Yang SS, Wang CC, Chen YT (2003) Effectiveness of alpha1-adrenergic blockers in boys with low urinary flow rate and urinary incontinence. J Formos Med Assoc 102(8):551–555PubMed
57.
go back to reference Kramer SA, Rathbun SR, Elkins D, Karnes RJ, Husmann DA (2005) Double-blind placebo controlled study of alpha-adrenergic receptor antagonists (doxazosin) for treatment of voiding dysfunction in the pediatric population. J Urol 173(6):2121–2124PubMedCrossRef Kramer SA, Rathbun SR, Elkins D, Karnes RJ, Husmann DA (2005) Double-blind placebo controlled study of alpha-adrenergic receptor antagonists (doxazosin) for treatment of voiding dysfunction in the pediatric population. J Urol 173(6):2121–2124PubMedCrossRef
58.
go back to reference Yucel S, Akkaya E, Guntekin E, Kukul E, Akman S, Melikoglu M et al (2005) Can alpha-blocker therapy be an alternative to biofeedback for dysfunctional voiding and urinary retention? A prospective study. J Urol 174(4 Pt 2):1612–1615PubMedCrossRef Yucel S, Akkaya E, Guntekin E, Kukul E, Akman S, Melikoglu M et al (2005) Can alpha-blocker therapy be an alternative to biofeedback for dysfunctional voiding and urinary retention? A prospective study. J Urol 174(4 Pt 2):1612–1615PubMedCrossRef
59.
go back to reference Schlager TA, Clark M, Anderson S (2001) Effect of a single-use sterile catheter for each void on the frequency of bacteriuria in children with neurogenic bladder on intermittent catheterization for bladder emptying. Pediatrics 108(4):E71PubMedCrossRef Schlager TA, Clark M, Anderson S (2001) Effect of a single-use sterile catheter for each void on the frequency of bacteriuria in children with neurogenic bladder on intermittent catheterization for bladder emptying. Pediatrics 108(4):E71PubMedCrossRef
Metadata
Title
Advances in non-surgical treatments for urinary tract infections in children
Authors
Stephen Shei-Dei Yang
I-Ni Chiang
Chia-Da Lin
Shang-Jen Chang
Publication date
01-02-2012
Publisher
Springer-Verlag
Published in
World Journal of Urology / Issue 1/2012
Print ISSN: 0724-4983
Electronic ISSN: 1433-8726
DOI
https://doi.org/10.1007/s00345-011-0700-5

Other articles of this Issue 1/2012

World Journal of Urology 1/2012 Go to the issue

Editorial

Editorial