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01-03-2007 | Topic Paper

Role of lymphadenectomy in clinically organ-confined prostate cancer

Authors: Nivedita Bhatta Dhar, Fiona C. Burkhard, Urs E. Studer

Published in: World Journal of Urology | Issue 1/2007

Abstract

There has been considerable debate about the utility of pelvic lymph node dissection (PLND) when performing a radical prostatectomy. Reported practices vary from those who always perform an extended PLND to those who employ a predictive nomogram in their decision making to those who are increasingly not performing a PLND in low-risk disease. A Medline search was used to identify relevant manuscripts dealing with the role of lymphadenectomy in clinically organ-confined prostate cancer. A greater number of lymph nodes (LN) removed and examined at prostatectomy for prostate cancer appears to increase the likelihood of finding LN metastases and increase prostate cancer-specific survival even in patients who have histologically uninvolved LN. This survival benefit may result from more accurate staging and possible removal of occult metastases. The need for and extent of PLND in prostate cancer, especially in low-risk disease, however, is unlikely.

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Title: Role of lymphadenectomy in clinically organ-confined prostate cancer
Authors: Nivedita Bhatta Dhar
Fiona C. Burkhard
Urs E. Studer
Publication date: 01-03-2007
Publisher: Springer-Verlag
Published in: World Journal of Urology / Issue 1/2007
Print ISSN: 0724-4983
Electronic ISSN: 1433-8726
DOI: https://doi.org/10.1007/s00345-007-0149-8

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