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World Journal of Urology
Published in: World Journal of Urology 3/2005

01-07-2005 | Topic Paper

Immunotherapy in metastatic renal cell carcinoma

Authors: Karl Rohrmann, Michael Staehler, Nikolas Haseke, Alexander Bachmann, Christian G. Stief, Michael Siebels

Published in: World Journal of Urology | Issue 3/2005

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Abstract

Metastatic renal cell carcinoma has a poor prognosis. Conventional therapies such as chemotherapy, radiation or hormonal treatment have hardly any effect on the progression of this disease. As renal cell carcinoma seems to be an immunogenic tumor, several immunotherapeutic approaches with different response rates have been developed since the early 1990s. We present an overview of various immunotherapeutic approaches such as cytokine-based regimes, with and without different cytotoxic chemotherapy, of metastatic renal cell carcinoma. In addition, local therapies (e.g. inhalation of interleukin-2) are reviewed.
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Metadata
Title
Immunotherapy in metastatic renal cell carcinoma
Authors
Karl Rohrmann
Michael Staehler
Nikolas Haseke
Alexander Bachmann
Christian G. Stief
Michael Siebels
Publication date
01-07-2005
Publisher
Springer-Verlag
Published in
World Journal of Urology / Issue 3/2005
Print ISSN: 0724-4983
Electronic ISSN: 1433-8726
DOI
https://doi.org/10.1007/s00345-004-0470-4

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