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Published in: European Radiology 6/2020

01-06-2020 | Coronavirus | Chest

Initial CT findings and temporal changes in patients with the novel coronavirus pneumonia (2019-nCoV): a study of 63 patients in Wuhan, China

Authors: Yueying Pan, Hanxiong Guan, Shuchang Zhou, Yujin Wang, Qian Li, Tingting Zhu, Qiongjie Hu, Liming Xia

Published in: European Radiology | Issue 6/2020

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Abstract

Objectives

The purpose of this study was to observe the imaging characteristics of the novel coronavirus pneumonia.

Methods

Sixty-three confirmed patients were enrolled from December 30, 2019 to January 31, 2020. High-resolution CT (HRCT) of the chest was performed. The number of affected lobes, ground glass nodules (GGO), patchy/punctate ground glass opacities, patchy consolidation, fibrous stripes and irregular solid nodules in each patient's chest CT image were recorded. Additionally, we performed imaging follow-up of these patients.

Results

CT images of 63 confirmed patients were collected. M/F ratio: 33/30. The mean age was 44.9 ± 15.2 years. The mean number of affected lobes was 3.3 ± 1.8. Nineteen (30.2%) patients had one affected lobe, five (7.9%) patients had two affected lobes, four (6.3%) patients had three affected lobes, seven (11.1%) patients had four affected lobes while 28 (44.4%) patients had 5 affected lobes. Fifty-four (85.7%) patients had patchy/punctate ground glass opacities, 14 (22.2%) patients had GGO, 12 (19.0%) patients had patchy consolidation, 11 (17.5%) patients had fibrous stripes and 8 (12.7%) patients had irregular solid nodules. Fifty-four (85.7%) patients progressed, including single GGO increased, enlarged and consolidated; fibrous stripe enlarged, while solid nodules increased and enlarged.

Conclusions

Imaging changes in novel viral pneumonia are rapid. The manifestations of the novel coronavirus pneumonia are diverse. Imaging changes of typical viral pneumonia and some specific imaging features were observed. Therefore, we need to strengthen the recognition of image changes to help clinicians to diagnose quickly and accurately.

Key Points

High-resolution CT (HRCT) of the chest is critical for early detection, evaluation of disease severity and follow-up of patients with the novel coronavirus pneumonia.
The manifestations of the novel coronavirus pneumonia are diverse and change rapidly.
Radiologists should be aware of the various features of the disease and temporal changes.
Literature
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Metadata
Title
Initial CT findings and temporal changes in patients with the novel coronavirus pneumonia (2019-nCoV): a study of 63 patients in Wuhan, China
Authors
Yueying Pan
Hanxiong Guan
Shuchang Zhou
Yujin Wang
Qian Li
Tingting Zhu
Qiongjie Hu
Liming Xia
Publication date
01-06-2020
Publisher
Springer Berlin Heidelberg
Published in
European Radiology / Issue 6/2020
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-020-06731-x

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