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Published in: European Radiology 9/2018

01-09-2018 | Cardiac

Automated estimation of image quality for coronary computed tomographic angiography using machine learning

Authors: Rine Nakanishi, Sethuraman Sankaran, Leo Grady, Jenifer Malpeso, Razik Yousfi, Kazuhiro Osawa, Indre Ceponiene, Negin Nazarat, Sina Rahmani, Kendall Kissel, Eranthi Jayawardena, Christopher Dailing, Christopher Zarins, Bon-Kwon Koo, James K. Min, Charles A. Taylor, Matthew J. Budoff

Published in: European Radiology | Issue 9/2018

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Abstract

Objectives

Our goal was to evaluate the efficacy of a fully automated method for assessing the image quality (IQ) of coronary computed tomography angiography (CCTA).

Methods

The machine learning method was trained using 75 CCTA studies by mapping features (noise, contrast, misregistration scores, and un-interpretability index) to an IQ score based on manual ground truth data. The automated method was validated on a set of 50 CCTA studies and subsequently tested on a new set of 172 CCTA studies against visual IQ scores on a 5-point Likert scale.

Results

The area under the curve in the validation set was 0.96. In the 172 CCTA studies, our method yielded a Cohen’s kappa statistic for the agreement between automated and visual IQ assessment of 0.67 (p < 0.01). In the group where good to excellent (n = 163), fair (n = 6), and poor visual IQ scores (n = 3) were graded, 155, 5, and 2 of the patients received an automated IQ score > 50 %, respectively.

Conclusion

Fully automated assessment of the IQ of CCTA data sets by machine learning was reproducible and provided similar results compared with visual analysis within the limits of inter-operator variability.

Key points

The proposed method enables automated and reproducible image quality assessment.
Machine learning and visual assessments yielded comparable estimates of image quality.
Automated assessment potentially allows for more standardised image quality.
Image quality assessment enables standardization of clinical trial results across different datasets.
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Metadata
Title
Automated estimation of image quality for coronary computed tomographic angiography using machine learning
Authors
Rine Nakanishi
Sethuraman Sankaran
Leo Grady
Jenifer Malpeso
Razik Yousfi
Kazuhiro Osawa
Indre Ceponiene
Negin Nazarat
Sina Rahmani
Kendall Kissel
Eranthi Jayawardena
Christopher Dailing
Christopher Zarins
Bon-Kwon Koo
James K. Min
Charles A. Taylor
Matthew J. Budoff
Publication date
01-09-2018
Publisher
Springer Berlin Heidelberg
Published in
European Radiology / Issue 9/2018
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-018-5348-8

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