Skip to main content
Top
Published in: European Radiology 7/2018

Open Access 01-07-2018 | Contrast Media

Post-contrast acute kidney injury. Part 2: risk stratification, role of hydration and other prophylactic measures, patients taking metformin and chronic dialysis patients

Recommendations for updated ESUR Contrast Medium Safety Committee guidelines

Authors: Aart J. van der Molen, Peter Reimer, Ilona A. Dekkers, Georg Bongartz, Marie-France Bellin, Michele Bertolotto, Olivier Clement, Gertraud Heinz-Peer, Fulvio Stacul, Judith A. W. Webb, Henrik S. Thomsen

Published in: European Radiology | Issue 7/2018

Login to get access

Abstract

Objectives

The Contrast Media Safety Committee (CMSC) of the European Society of Urogenital Radiology (ESUR) has updated its 2011 guidelines on the prevention of post-contrast acute kidney injury (PC-AKI). The results of the literature review and the recommendations based on it, which were used to prepare the new guidelines, are presented in two papers.

Areas covered in part 2

Topics reviewed include stratification of PC-AKI risk, the need to withdraw nephrotoxic medication, PC-AKI prophylaxis with hydration or drugs, the use of metformin in diabetic patients receiving contrast medium and the need to alter dialysis schedules in patients receiving contrast medium.

Key points

• In CKD, hydration reduces the PC-AKI risk
• Intravenous normal saline and intravenous sodium bicarbonate provide equally effective prophylaxis
• No drugs have been consistently shown to reduce the risk of PC-AKI
• Stop metformin from the time of contrast medium administration if eGFR < 30 ml/min/1.73 m 2
• Dialysis schedules need not change when intravascular contrast medium is given
Literature
1.
go back to reference Stacul F, van der Molen AJ, Reimer P, Contrast Media Safety Committee of European Society of Urogenital Radiology (ESUR) et al (2011) Contrast induced nephropathy: updated ESUR Contrast Media Safety Committee guidelines. Eur Radiol 21:2527–2541PubMedCrossRef Stacul F, van der Molen AJ, Reimer P, Contrast Media Safety Committee of European Society of Urogenital Radiology (ESUR) et al (2011) Contrast induced nephropathy: updated ESUR Contrast Media Safety Committee guidelines. Eur Radiol 21:2527–2541PubMedCrossRef
2.
go back to reference Morcos SK, Thomsen HS, Webb JA, Contrast Media Safety Committee of the European Society of Urogenital Radiology (ESUR) et al (2002) Dialysis and contrast media. Eur Radiol 12:3026–3030PubMed Morcos SK, Thomsen HS, Webb JA, Contrast Media Safety Committee of the European Society of Urogenital Radiology (ESUR) et al (2002) Dialysis and contrast media. Eur Radiol 12:3026–3030PubMed
4.
go back to reference Brouwers M, Kho ME, Browman GP, on behalf of the AGREE Next Steps Consortium et al (2010) AGREE II: Advancing guideline development, reporting and evaluation in healthcare. Can Med Assoc J 182:E839–E842CrossRef Brouwers M, Kho ME, Browman GP, on behalf of the AGREE Next Steps Consortium et al (2010) AGREE II: Advancing guideline development, reporting and evaluation in healthcare. Can Med Assoc J 182:E839–E842CrossRef
5.
go back to reference Guyatt GH, Oxman AD, Kunz R et al (2011) GRADE guidelines: 2. Framing the question and deciding on important outcomes. J Clin Epidemiol 64:395–400PubMedCrossRef Guyatt GH, Oxman AD, Kunz R et al (2011) GRADE guidelines: 2. Framing the question and deciding on important outcomes. J Clin Epidemiol 64:395–400PubMedCrossRef
7.
go back to reference Choyke PL, Cady J, DePollar SL, Austin H (1998) Determination of serum creatinine prior to iodinated contrast media: is it necessary in all patients? Tech Urol 4:65–69PubMed Choyke PL, Cady J, DePollar SL, Austin H (1998) Determination of serum creatinine prior to iodinated contrast media: is it necessary in all patients? Tech Urol 4:65–69PubMed
8.
go back to reference Tippins RB, Torres WE, Baumgartner BR, Baumgarten DA (2000) Are screening serum creatinine levels necessary prior to outpatient CT examinations? Radiology 216:481–484PubMedCrossRef Tippins RB, Torres WE, Baumgartner BR, Baumgarten DA (2000) Are screening serum creatinine levels necessary prior to outpatient CT examinations? Radiology 216:481–484PubMedCrossRef
9.
go back to reference Azzouz M, Romsing J, Thomsen HS (2014) Can a structured questionnaire identify patients with reduced renal function? Eur Radiol 24:780–784PubMedCrossRef Azzouz M, Romsing J, Thomsen HS (2014) Can a structured questionnaire identify patients with reduced renal function? Eur Radiol 24:780–784PubMedCrossRef
10.
go back to reference Too CW, Ng WY, Tan CC, Mahmood MI, Tay KH (2015) Screening for impaired renal function in outpatients before iodinated contrast injection: comparing the Choyke questionnaire with a rapid point-of-care-test. Eur J Radiol 84:1227–1231PubMedCrossRef Too CW, Ng WY, Tan CC, Mahmood MI, Tay KH (2015) Screening for impaired renal function in outpatients before iodinated contrast injection: comparing the Choyke questionnaire with a rapid point-of-care-test. Eur J Radiol 84:1227–1231PubMedCrossRef
11.
go back to reference Zähringer C, Potthast S, Tyndall AJ, Bongartz G, Hohmann J (2015) Serum creatinine measurements: evaluation of a questionnaire according to the ESUR guidelines. Acta Radiol 56:628–634PubMedCrossRef Zähringer C, Potthast S, Tyndall AJ, Bongartz G, Hohmann J (2015) Serum creatinine measurements: evaluation of a questionnaire according to the ESUR guidelines. Acta Radiol 56:628–634PubMedCrossRef
12.
go back to reference Chang P, Saddleton E, Laumann AE et al (2012) Comparison of the sensitivity of a pre-MRI questionnaire and point of care eGFR testing for detection of impaired renal function. Acad Radiol 19:1181–1185PubMedPubMedCentralCrossRef Chang P, Saddleton E, Laumann AE et al (2012) Comparison of the sensitivity of a pre-MRI questionnaire and point of care eGFR testing for detection of impaired renal function. Acad Radiol 19:1181–1185PubMedPubMedCentralCrossRef
13.
go back to reference Moos SI, de Weijert RS, Nagan G, Stoker J, Bipat S (2014) Cost of screening for kidney disease before intravenous contrast administration. Neth J Med 72:271–280PubMed Moos SI, de Weijert RS, Nagan G, Stoker J, Bipat S (2014) Cost of screening for kidney disease before intravenous contrast administration. Neth J Med 72:271–280PubMed
15.
go back to reference Tsai TT, Patel UD, Chang TI et al (2014) Validated contemporary risk model of acute kidney injury in patients undergoing percutaneous coronary interventions: insights from the National Cardiovascular Data Registry Cath-PCI Registry. J Am Heart Assoc 3:e001380PubMedPubMedCentralCrossRef Tsai TT, Patel UD, Chang TI et al (2014) Validated contemporary risk model of acute kidney injury in patients undergoing percutaneous coronary interventions: insights from the National Cardiovascular Data Registry Cath-PCI Registry. J Am Heart Assoc 3:e001380PubMedPubMedCentralCrossRef
16.
go back to reference Kooiman J, Gurm HS (2014) Predicting contrast-induced renal complications in the catheterization laboratory. Intervent Cardiol Clin 3:369–377PubMedCrossRef Kooiman J, Gurm HS (2014) Predicting contrast-induced renal complications in the catheterization laboratory. Intervent Cardiol Clin 3:369–377PubMedCrossRef
17.
go back to reference Mehran R, Aymong ED, Nikolsky E et al (2004) A simple risk score for prediction of contrast-induced nephropathy after percutaneous coronary intervention: development and initial validation. J Am Coll Cardiol 44:1393–1399PubMed Mehran R, Aymong ED, Nikolsky E et al (2004) A simple risk score for prediction of contrast-induced nephropathy after percutaneous coronary intervention: development and initial validation. J Am Coll Cardiol 44:1393–1399PubMed
18.
go back to reference Sgura FA, Bertelli L, Monopoli D et al (2010) Mehran contrast-induced nephropathy risk score predicts short- and long-term clinical outcomes in patients with ST-elevation-myocardial infarction. Circ Cardiovasc Interv 3:491–498PubMedCrossRef Sgura FA, Bertelli L, Monopoli D et al (2010) Mehran contrast-induced nephropathy risk score predicts short- and long-term clinical outcomes in patients with ST-elevation-myocardial infarction. Circ Cardiovasc Interv 3:491–498PubMedCrossRef
19.
go back to reference Tziakas D, Chalikias G, Stakos D et al (2014) Validation of a new risk score to predict contrast-induced nephropathy after percutaneous coronary intervention. Am J Cardiol 113:1487–1493PubMedCrossRef Tziakas D, Chalikias G, Stakos D et al (2014) Validation of a new risk score to predict contrast-induced nephropathy after percutaneous coronary intervention. Am J Cardiol 113:1487–1493PubMedCrossRef
20.
go back to reference Abellas-Sequeiros RA, Raposeiras-Roubin S, Abu-Assi E et al (2016) Mehran contrast nephropathy risk score: is it still useful 10 years later? J Cardiol 67:262–267PubMedCrossRef Abellas-Sequeiros RA, Raposeiras-Roubin S, Abu-Assi E et al (2016) Mehran contrast nephropathy risk score: is it still useful 10 years later? J Cardiol 67:262–267PubMedCrossRef
21.
go back to reference Sato A, Hoshi T, Kakefuda Y et al (2015) Effect of the Mehran risk score for the prediction of clinical outcomes after percutaneous coronary intervention. J Cardiol 66:417–422PubMedCrossRef Sato A, Hoshi T, Kakefuda Y et al (2015) Effect of the Mehran risk score for the prediction of clinical outcomes after percutaneous coronary intervention. J Cardiol 66:417–422PubMedCrossRef
22.
go back to reference Gurm HS, Seth M, Kooiman J, Share D (2013) A novel tool for reliable and accurate prediction of renal complications in patients undergoing percutaneous coronary intervention. J Am Coll Cardiol 61:2242–2248PubMedCrossRef Gurm HS, Seth M, Kooiman J, Share D (2013) A novel tool for reliable and accurate prediction of renal complications in patients undergoing percutaneous coronary intervention. J Am Coll Cardiol 61:2242–2248PubMedCrossRef
23.
go back to reference Silver SA, Shah PS, Chertow GM, Harel S, Wald R, Harel Z (2015) Risk prediction models for contrast induced nephropathy: systematic review. BMJ 351:h4395PubMedPubMedCentralCrossRef Silver SA, Shah PS, Chertow GM, Harel S, Wald R, Harel Z (2015) Risk prediction models for contrast induced nephropathy: systematic review. BMJ 351:h4395PubMedPubMedCentralCrossRef
24.
go back to reference Allen DW, Ma B, Leung KC et al (2017) Risk prediction models for contrast-induced acute kidney injury accompanying cardiac catheterization: systematic review and meta-analysis. Can J Cardiol 33(6):724-736 Allen DW, Ma B, Leung KC et al (2017) Risk prediction models for contrast-induced acute kidney injury accompanying cardiac catheterization: systematic review and meta-analysis. Can J Cardiol 33(6):724-736
26.
27.
go back to reference Diogo LP, Saitovitch D, Biehl M et al (2010) Is there an association between non-steroidal anti-inflammatory drugs and contrast nephropathy? Arq Bras Cardiol 95:726–731PubMedCrossRef Diogo LP, Saitovitch D, Biehl M et al (2010) Is there an association between non-steroidal anti-inflammatory drugs and contrast nephropathy? Arq Bras Cardiol 95:726–731PubMedCrossRef
28.
go back to reference Ho YF, Hsieh KL, Kung FL, et al (2015) Nephrotoxic polypharmacy and risk of contrast medium-induced nephropathy in hospitalized patients undergoing contrast-enhanced CT. AJR Am J Roentgenol 205:703–708 Ho YF, Hsieh KL, Kung FL, et al (2015) Nephrotoxic polypharmacy and risk of contrast medium-induced nephropathy in hospitalized patients undergoing contrast-enhanced CT. AJR Am J Roentgenol 205:703–708
29.
go back to reference Moos SI, van Vemde DN, Stoker J, Bipat S (2013) Contrast induced nephropathy in patients undergoing intravenous (IV) contrast enhanced computed tomography (CECT) and the relationship with risk factors: a meta-analysis. Eur J Radiol 82:e387–e399PubMedCrossRef Moos SI, van Vemde DN, Stoker J, Bipat S (2013) Contrast induced nephropathy in patients undergoing intravenous (IV) contrast enhanced computed tomography (CECT) and the relationship with risk factors: a meta-analysis. Eur J Radiol 82:e387–e399PubMedCrossRef
30.
go back to reference Rosenstock JL, Bruno R, Kim JK et al (2008) The effect of withdrawal of ACE inhibitors or angiotensin receptor blockers prior to coronary angiography on the incidence of contrast-induced nephropathy. Int Urol Nephrol 40:749–755PubMedCrossRef Rosenstock JL, Bruno R, Kim JK et al (2008) The effect of withdrawal of ACE inhibitors or angiotensin receptor blockers prior to coronary angiography on the incidence of contrast-induced nephropathy. Int Urol Nephrol 40:749–755PubMedCrossRef
31.
go back to reference Bainey KR, Rahim S, Etherington K, CAPTAIN Investigators et al (2015) Effects of withdrawing vs. continuing renin-angiotensin blockers on incidence of acute kidney injury in patients with renal insufficiency undergoing cardiac catheterization: results from the angiotensin converting enzyme inhibitor/angiotensin receptor blocker and contrast induced nephropathy in patients receiving cardiac catheterization (CAPTAIN) trial. Am Heart J 170:110–116PubMedCrossRef Bainey KR, Rahim S, Etherington K, CAPTAIN Investigators et al (2015) Effects of withdrawing vs. continuing renin-angiotensin blockers on incidence of acute kidney injury in patients with renal insufficiency undergoing cardiac catheterization: results from the angiotensin converting enzyme inhibitor/angiotensin receptor blocker and contrast induced nephropathy in patients receiving cardiac catheterization (CAPTAIN) trial. Am Heart J 170:110–116PubMedCrossRef
32.
go back to reference Jo SH, Lee JM, Park J, Kim HS (2015) The impact of renin-angiotensin-aldosterone system blockade on contrast-induced nephropathy: a meta-analysis of 12 studies with 4,493 patients. Cardiology 130:4–14PubMedCrossRef Jo SH, Lee JM, Park J, Kim HS (2015) The impact of renin-angiotensin-aldosterone system blockade on contrast-induced nephropathy: a meta-analysis of 12 studies with 4,493 patients. Cardiology 130:4–14PubMedCrossRef
33.
go back to reference Peng F, Su J, Lin J, Niu W (2015) Impact of renin-angiotensin-aldosterone system-blocking agents on the risk of contrast-induced acute kidney injury: a prospective study and meta-analysis. J Cardiovasc Pharmacol 65:262–268PubMedCrossRef Peng F, Su J, Lin J, Niu W (2015) Impact of renin-angiotensin-aldosterone system-blocking agents on the risk of contrast-induced acute kidney injury: a prospective study and meta-analysis. J Cardiovasc Pharmacol 65:262–268PubMedCrossRef
34.
go back to reference Wu Z, Zhang H, Jin W et al (2015) The effect of renin-angiotensin-aldosterone system blockade medications on contrast-induced nephropathy in patients undergoing coronary angiography: a meta-analysis. PLoS One 10:e0129747PubMedPubMedCentralCrossRef Wu Z, Zhang H, Jin W et al (2015) The effect of renin-angiotensin-aldosterone system blockade medications on contrast-induced nephropathy in patients undergoing coronary angiography: a meta-analysis. PLoS One 10:e0129747PubMedPubMedCentralCrossRef
35.
go back to reference Chen SL, Zhang J, Yei F et al (2008) Clinical outcomes of contrast-induced nephropathy in patients undergoing percutaneous coronary intervention: a prospective, multicenter, randomized study to analyze the effect of hydration and acetylcysteine. Int J Cardiol 126:407–413PubMedCrossRef Chen SL, Zhang J, Yei F et al (2008) Clinical outcomes of contrast-induced nephropathy in patients undergoing percutaneous coronary intervention: a prospective, multicenter, randomized study to analyze the effect of hydration and acetylcysteine. Int J Cardiol 126:407–413PubMedCrossRef
36.
go back to reference Luo Y, Wang X, Ye Z, et al (2014) Remedial hydration reduces the incidence of contrast-induced nephropathy and short-term adverse events in patients with ST-segment elevation myocardial infarction: a single-center, randomized trial. Intern Med 53:2265–2272 Luo Y, Wang X, Ye Z, et al (2014) Remedial hydration reduces the incidence of contrast-induced nephropathy and short-term adverse events in patients with ST-segment elevation myocardial infarction: a single-center, randomized trial. Intern Med 53:2265–2272
37.
go back to reference Jurado-Roman A, Hernandez-Hernandez F, Garcia-Tejada J et al (2015) Role of hydration in contrast-induced nephropathy in patients who underwent primary percutaneous coronary intervention. Am J Cardiol 115:1174–1178PubMedCrossRef Jurado-Roman A, Hernandez-Hernandez F, Garcia-Tejada J et al (2015) Role of hydration in contrast-induced nephropathy in patients who underwent primary percutaneous coronary intervention. Am J Cardiol 115:1174–1178PubMedCrossRef
38.
go back to reference Kooiman J, Sijpkens YW, van Buren M et al (2014) Randomised trial of no hydration vs. sodium bicarbonate hydration in patients with chronic kidney disease undergoing acute computed tomography-pulmonary angiography. J Thromb Haemost 12:1658–1666PubMedCrossRef Kooiman J, Sijpkens YW, van Buren M et al (2014) Randomised trial of no hydration vs. sodium bicarbonate hydration in patients with chronic kidney disease undergoing acute computed tomography-pulmonary angiography. J Thromb Haemost 12:1658–1666PubMedCrossRef
39.
go back to reference Trivedi HS, Moore H, Nasr S et al (2003) A randomized prospective trial to assess the role of saline hydration on the development of contrast nephrotoxicity. Nephron Clin Pract 93:C29–C34PubMedCrossRef Trivedi HS, Moore H, Nasr S et al (2003) A randomized prospective trial to assess the role of saline hydration on the development of contrast nephrotoxicity. Nephron Clin Pract 93:C29–C34PubMedCrossRef
40.
go back to reference Nijssen EC, Rennenberg RJ, Nelemans PJ et al (2017) Prophylactic hydration to protect renal function from intravascular iodinated contrast material in patients at high risk of contrast-induced nephropathy (AMACING): a prospective, randomised, phase 3, controlled, open-label, non-inferiority trial. Lancet 389:1312–1322PubMedCrossRef Nijssen EC, Rennenberg RJ, Nelemans PJ et al (2017) Prophylactic hydration to protect renal function from intravascular iodinated contrast material in patients at high risk of contrast-induced nephropathy (AMACING): a prospective, randomised, phase 3, controlled, open-label, non-inferiority trial. Lancet 389:1312–1322PubMedCrossRef
41.
go back to reference Taylor AJ, Hotchkiss D, Morse RW, McCabe J (1998) PREPARED: preparation for Angiography in Renal Dysfunction: a randomized trial of inpatient vs outpatient hydration protocols for cardiac catheterization in mild-to-moderate renal dysfunction. Chest 114:1570–1574PubMedCrossRef Taylor AJ, Hotchkiss D, Morse RW, McCabe J (1998) PREPARED: preparation for Angiography in Renal Dysfunction: a randomized trial of inpatient vs outpatient hydration protocols for cardiac catheterization in mild-to-moderate renal dysfunction. Chest 114:1570–1574PubMedCrossRef
42.
go back to reference Dussol B, Morange S, Loundoun A, Auquier P, Berland Y (2006) A randomized trial of saline hydration to prevent contrast nephropathy in chronic renal failure patients. Nephrol Dial Transplant 21:2120–2126PubMedCrossRef Dussol B, Morange S, Loundoun A, Auquier P, Berland Y (2006) A randomized trial of saline hydration to prevent contrast nephropathy in chronic renal failure patients. Nephrol Dial Transplant 21:2120–2126PubMedCrossRef
43.
go back to reference Lawlor DK, Moist L, DeRose G et al (2007) Prevention of contrast-induced nephropathy in vascular surgery patients. Ann Vasc Surg 21:593–597PubMedCrossRef Lawlor DK, Moist L, DeRose G et al (2007) Prevention of contrast-induced nephropathy in vascular surgery patients. Ann Vasc Surg 21:593–597PubMedCrossRef
44.
go back to reference Wrobel W, Sinkiewicz W, Gordon M, Wozniak-Wisniewska A (2010) Oral versus intravenous hydration and renal function in diabetic patients undergoing percutaneous coronary interventions. Kardiol Pol 68:1015–1020PubMed Wrobel W, Sinkiewicz W, Gordon M, Wozniak-Wisniewska A (2010) Oral versus intravenous hydration and renal function in diabetic patients undergoing percutaneous coronary interventions. Kardiol Pol 68:1015–1020PubMed
45.
go back to reference Akyuz S, Karaca M, Kemaloglu OT et al (2014) Efficacy of oral hydration in the prevention of contrast-induced acute kidney injury in patients undergoing coronary angiography or intervention. Nephron Clin Pract 128:95–100PubMedCrossRef Akyuz S, Karaca M, Kemaloglu OT et al (2014) Efficacy of oral hydration in the prevention of contrast-induced acute kidney injury in patients undergoing coronary angiography or intervention. Nephron Clin Pract 128:95–100PubMedCrossRef
46.
go back to reference Cho R, Javed N, Traub D, Kodali S, Atem F, Srinivasan V (2010) Oral hydration and alkalinization is noninferior to intravenous therapy for prevention of contrast-induced nephropathy in patients with chronic kidney disease. J Interv Cardiol 23:460–466PubMedCrossRef Cho R, Javed N, Traub D, Kodali S, Atem F, Srinivasan V (2010) Oral hydration and alkalinization is noninferior to intravenous therapy for prevention of contrast-induced nephropathy in patients with chronic kidney disease. J Interv Cardiol 23:460–466PubMedCrossRef
47.
go back to reference Kong DG, Hou YF, Ma LL, Yao DK, Wang LX (2012) Comparison of oral and intravenous hydration strategies for the prevention of contrast-induced nephropathy in patients undergoing coronary angiography or angioplasty: a randomized clinical trial. Acta Cardiol 67:565–569PubMedCrossRef Kong DG, Hou YF, Ma LL, Yao DK, Wang LX (2012) Comparison of oral and intravenous hydration strategies for the prevention of contrast-induced nephropathy in patients undergoing coronary angiography or angioplasty: a randomized clinical trial. Acta Cardiol 67:565–569PubMedCrossRef
48.
go back to reference Martin-Moreno PL, Varo N, Martinez-Anso E et al (2015) Comparison of intravenous and oral hydration in the prevention of contrast-induced acute kidney injury in low-risk patients: a randomized trial. Nephron 131:51–58PubMedCrossRef Martin-Moreno PL, Varo N, Martinez-Anso E et al (2015) Comparison of intravenous and oral hydration in the prevention of contrast-induced acute kidney injury in low-risk patients: a randomized trial. Nephron 131:51–58PubMedCrossRef
49.
go back to reference Hiremath S, Akbari A, Shabana W, Fergusson DA, Knoll GA (2013) Prevention of contrast-induced acute kidney injury: is simple oral hydration similar to intravenous? A systematic review of the evidence. PLoS One 8:e60009PubMedPubMedCentralCrossRef Hiremath S, Akbari A, Shabana W, Fergusson DA, Knoll GA (2013) Prevention of contrast-induced acute kidney injury: is simple oral hydration similar to intravenous? A systematic review of the evidence. PLoS One 8:e60009PubMedPubMedCentralCrossRef
50.
go back to reference Cheungpasitporn W, Thongprayoon C, Brabec BA, Edmonds PJ, O'Corragain OA, Erickson SB (2014) Oral hydration for prevention of contrast-induced acute kidney injury in elective radiological procedures: a systematic review and meta-analysis of randomized controlled trials. N Am J Med Sci 6:618–624PubMedPubMedCentralCrossRef Cheungpasitporn W, Thongprayoon C, Brabec BA, Edmonds PJ, O'Corragain OA, Erickson SB (2014) Oral hydration for prevention of contrast-induced acute kidney injury in elective radiological procedures: a systematic review and meta-analysis of randomized controlled trials. N Am J Med Sci 6:618–624PubMedPubMedCentralCrossRef
51.
go back to reference Agarwal SK, Mohareb S, Patel A et al (2015) Systematic oral hydration with water is similar to parenteral hydration for prevention of contrast-induced nephropathy: an updated meta-analysis of randomised clinical data. Open Heart 2:e000317PubMedPubMedCentralCrossRef Agarwal SK, Mohareb S, Patel A et al (2015) Systematic oral hydration with water is similar to parenteral hydration for prevention of contrast-induced nephropathy: an updated meta-analysis of randomised clinical data. Open Heart 2:e000317PubMedPubMedCentralCrossRef
52.
go back to reference Heyman SN, Rosen S, Khamaisi M, Idée JM, Rosenberger C (2010) Reactive oxygen species and the pathogenesis of radiocontrast-induced nephorpathy. Invest Radiol 45:188–193PubMedCrossRef Heyman SN, Rosen S, Khamaisi M, Idée JM, Rosenberger C (2010) Reactive oxygen species and the pathogenesis of radiocontrast-induced nephorpathy. Invest Radiol 45:188–193PubMedCrossRef
53.
go back to reference Merten GJ, Burgess WP, Gray LV et al (2004) Prevention of contrast-induced nephropathy with sodium bicarbonate: a randomized controlled trial. JAMA 291:2328–2334PubMedCrossRef Merten GJ, Burgess WP, Gray LV et al (2004) Prevention of contrast-induced nephropathy with sodium bicarbonate: a randomized controlled trial. JAMA 291:2328–2334PubMedCrossRef
54.
go back to reference Masuda M, Yamada T, Mine T et al (2007) Comparison of usefulness of sodium bicarbonate versus sodium chloride to prevent contrast-induced nephropathy in patients undergoing an emergent coronary procedure. Am J Cardiol 100:781–786PubMedCrossRef Masuda M, Yamada T, Mine T et al (2007) Comparison of usefulness of sodium bicarbonate versus sodium chloride to prevent contrast-induced nephropathy in patients undergoing an emergent coronary procedure. Am J Cardiol 100:781–786PubMedCrossRef
55.
go back to reference Ozcan EE, Guneri S, Akdeniz B et al (2007) Sodium bicarbonate, N-acetylcysteine, and saline for prevention of radiocontrast-induced nephropathy. A comparison of 3 regimens for protecting contrast-induced nephropathy in patients undergoing coronary procedures. A single-center prospective controlled trial. Am Heart J 154:539–544PubMedCrossRef Ozcan EE, Guneri S, Akdeniz B et al (2007) Sodium bicarbonate, N-acetylcysteine, and saline for prevention of radiocontrast-induced nephropathy. A comparison of 3 regimens for protecting contrast-induced nephropathy in patients undergoing coronary procedures. A single-center prospective controlled trial. Am Heart J 154:539–544PubMedCrossRef
56.
go back to reference Recio-Mayoral A, Chaparro M, Prado B et al (2007) The reno-protective effect of hydration with sodium bicarbonate plus N-acetylcysteine in patients undergoing emergency percutaneous coronary intervention: the RENO Study. J Am Coll Cardiol 49:1283–1288PubMedCrossRef Recio-Mayoral A, Chaparro M, Prado B et al (2007) The reno-protective effect of hydration with sodium bicarbonate plus N-acetylcysteine in patients undergoing emergency percutaneous coronary intervention: the RENO Study. J Am Coll Cardiol 49:1283–1288PubMedCrossRef
57.
go back to reference Adolph E, Holdt-Lehmann B, Chatterjee T et al (2008) Renal Insufficiency Following Radiocontrast Exposure Trial (REINFORCE): a randomized comparison of sodium bicarbonate versus sodium chloride hydration for the prevention of contrast-induced nephropathy. Coron Artery Dis 19:413–419PubMed Adolph E, Holdt-Lehmann B, Chatterjee T et al (2008) Renal Insufficiency Following Radiocontrast Exposure Trial (REINFORCE): a randomized comparison of sodium bicarbonate versus sodium chloride hydration for the prevention of contrast-induced nephropathy. Coron Artery Dis 19:413–419PubMed
58.
go back to reference Brar SS, Shen AY, Jorgensen MB et al (2008) Sodium bicarbonate vs sodium chloride for the prevention of contrast medium-induced nephropathy in patients undergoing coronary angiography: a randomized trial. JAMA 300:1038–1046PubMedCrossRef Brar SS, Shen AY, Jorgensen MB et al (2008) Sodium bicarbonate vs sodium chloride for the prevention of contrast medium-induced nephropathy in patients undergoing coronary angiography: a randomized trial. JAMA 300:1038–1046PubMedCrossRef
59.
go back to reference Boucek P, Havrdova T, Oliyarnyk O et al (2013) Prevention of contrast-induced nephropathy in diabetic patients with impaired renal function: a randomized, double blind trial of sodium bicarbonate versus sodium chloride-based hydration. Diabetes Res Clin Pract 101:303–308PubMedCrossRef Boucek P, Havrdova T, Oliyarnyk O et al (2013) Prevention of contrast-induced nephropathy in diabetic patients with impaired renal function: a randomized, double blind trial of sodium bicarbonate versus sodium chloride-based hydration. Diabetes Res Clin Pract 101:303–308PubMedCrossRef
60.
go back to reference Gomes VO, Lasevitch R, Lima VC et al (2012) Hydration with sodium bicarbonate does not prevent contrast nephropathy: a multicenter clinical trial. Arq Bras Cardiol 99:1129–1134PubMedCrossRef Gomes VO, Lasevitch R, Lima VC et al (2012) Hydration with sodium bicarbonate does not prevent contrast nephropathy: a multicenter clinical trial. Arq Bras Cardiol 99:1129–1134PubMedCrossRef
61.
go back to reference Ratcliffe JA, Thiagarajah P, Chen J et al (2009) Prevention of contrast-induced nephropathy: a randomized controlled trial of sodium bicarbonate and N-acetylcysteine. Int J Angiol 18:193–197PubMedPubMedCentralCrossRef Ratcliffe JA, Thiagarajah P, Chen J et al (2009) Prevention of contrast-induced nephropathy: a randomized controlled trial of sodium bicarbonate and N-acetylcysteine. Int J Angiol 18:193–197PubMedPubMedCentralCrossRef
62.
go back to reference Solomon R, Gordon P, Manoukian SV et al (2015) Randomized trial of bicarbonate or saline study for the prevention of contrast-induced nephropathy in patients with CKD. Clin J Am Soc Nephrol 10:1519–1524PubMedPubMedCentralCrossRef Solomon R, Gordon P, Manoukian SV et al (2015) Randomized trial of bicarbonate or saline study for the prevention of contrast-induced nephropathy in patients with CKD. Clin J Am Soc Nephrol 10:1519–1524PubMedPubMedCentralCrossRef
63.
go back to reference Briguori C, Airoldi F, D'Andrea D et al (2007) Renal Insufficiency Following Contrast Media Administration Trial (REMEDIAL): a randomized comparison of 3 preventive strategies. Circulation 115:1211–1217PubMed Briguori C, Airoldi F, D'Andrea D et al (2007) Renal Insufficiency Following Contrast Media Administration Trial (REMEDIAL): a randomized comparison of 3 preventive strategies. Circulation 115:1211–1217PubMed
64.
go back to reference Castini D, Lucreziotti S, Bosotti L et al (2010) Prevention of contrast-induced nephropathy: a single center randomized study. Clin Cardiol 33:E63–E68PubMedCrossRefPubMedCentral Castini D, Lucreziotti S, Bosotti L et al (2010) Prevention of contrast-induced nephropathy: a single center randomized study. Clin Cardiol 33:E63–E68PubMedCrossRefPubMedCentral
65.
go back to reference Chong E, Poh KK, Lu Q et al (2015) Comparison of combination therapy of high-dose oral N-acetylcysteine and intravenous sodium bicarbonate hydration with individual therapies in the reduction of Contrast-induced Nephropathy during Cardiac Catheterisation and Percutaneous Coronary Intervention (CONTRAST): a multi-centre, randomised, controlled trial. Int J Cardiol 201:237–242PubMedCrossRef Chong E, Poh KK, Lu Q et al (2015) Comparison of combination therapy of high-dose oral N-acetylcysteine and intravenous sodium bicarbonate hydration with individual therapies in the reduction of Contrast-induced Nephropathy during Cardiac Catheterisation and Percutaneous Coronary Intervention (CONTRAST): a multi-centre, randomised, controlled trial. Int J Cardiol 201:237–242PubMedCrossRef
66.
go back to reference Hafiz AM, Jan MF, Mori N et al (2012) Prevention of contrast-induced acute kidney injury in patients with stable chronic renal disease undergoing elective percutaneous coronary and peripheral interventions: randomized comparison of two preventive strategies. Catheter Cardiovasc Interv 79:929–937PubMedCrossRef Hafiz AM, Jan MF, Mori N et al (2012) Prevention of contrast-induced acute kidney injury in patients with stable chronic renal disease undergoing elective percutaneous coronary and peripheral interventions: randomized comparison of two preventive strategies. Catheter Cardiovasc Interv 79:929–937PubMedCrossRef
67.
go back to reference Koc F, Ozdemir K, Altunkas F et al (2013) Sodium bicarbonate versus isotonic saline for the prevention of contrast-induced nephropathy in patients with diabetes mellitus undergoing coronary angiography and/or intervention: a multicenter prospective randomized study. J Investig Med 61:872–877PubMedCrossRef Koc F, Ozdemir K, Altunkas F et al (2013) Sodium bicarbonate versus isotonic saline for the prevention of contrast-induced nephropathy in patients with diabetes mellitus undergoing coronary angiography and/or intervention: a multicenter prospective randomized study. J Investig Med 61:872–877PubMedCrossRef
68.
go back to reference Klima T, Christ A, Marana I et al (2012) Sodium chloride vs. sodium bicarbonate for the prevention of contrast medium-induced nephropathy: a randomized controlled trial. Eur Heart J 33:2071–2079PubMedCrossRef Klima T, Christ A, Marana I et al (2012) Sodium chloride vs. sodium bicarbonate for the prevention of contrast medium-induced nephropathy: a randomized controlled trial. Eur Heart J 33:2071–2079PubMedCrossRef
69.
go back to reference Lee SW, Kim WJ, Kim YH et al (2011) Preventive strategies of renal insufficiency in patients with diabetes undergoing intervention or arteriography (the PREVENT Trial). Am J Cardiol 107:1447–1452PubMedCrossRef Lee SW, Kim WJ, Kim YH et al (2011) Preventive strategies of renal insufficiency in patients with diabetes undergoing intervention or arteriography (the PREVENT Trial). Am J Cardiol 107:1447–1452PubMedCrossRef
70.
go back to reference Maioli M, Toso A, Leoncini M et al (2008) Sodium bicarbonate versus saline for the prevention of contrast-induced nephropathy in patients with renal dysfunction undergoing coronary angiography or intervention. J Am Coll Cardiol 52:599–604PubMedCrossRef Maioli M, Toso A, Leoncini M et al (2008) Sodium bicarbonate versus saline for the prevention of contrast-induced nephropathy in patients with renal dysfunction undergoing coronary angiography or intervention. J Am Coll Cardiol 52:599–604PubMedCrossRef
71.
go back to reference Shavit L, Korenfeld R, Lifschitz M, Butnaru A, Slotki I (2009) Sodium bicarbonate versus sodium chloride and oral N-acetylcysteine for the prevention of contrast-induced nephropathy in advanced chronic kidney disease. J Interv Cardiol 22:556–563PubMedCrossRef Shavit L, Korenfeld R, Lifschitz M, Butnaru A, Slotki I (2009) Sodium bicarbonate versus sodium chloride and oral N-acetylcysteine for the prevention of contrast-induced nephropathy in advanced chronic kidney disease. J Interv Cardiol 22:556–563PubMedCrossRef
72.
go back to reference Kooiman J, Sijpkens YW, de Vries JP et al (2014) A randomized comparison of 1-h sodium bicarbonate hydration versus standard peri-procedural saline hydration in patients with chronic kidney disease undergoing intravenous contrast-enhanced computerized tomography. Nephrol Dial Transplant 29:1029–1036PubMedCrossRef Kooiman J, Sijpkens YW, de Vries JP et al (2014) A randomized comparison of 1-h sodium bicarbonate hydration versus standard peri-procedural saline hydration in patients with chronic kidney disease undergoing intravenous contrast-enhanced computerized tomography. Nephrol Dial Transplant 29:1029–1036PubMedCrossRef
73.
go back to reference Kooiman J, de Vries JP, van der Heyden J et al (2014) Randomized trial of 1-hour sodium bicarbonate vs. Standard saline hydration in patients with chronic kidney disease undergoing intra-arterial contrast administration [abstr]. Circulation 130:A17645 Kooiman J, de Vries JP, van der Heyden J et al (2014) Randomized trial of 1-hour sodium bicarbonate vs. Standard saline hydration in patients with chronic kidney disease undergoing intra-arterial contrast administration [abstr]. Circulation 130:A17645
74.
go back to reference Kama A, Yilmaz S, Yaka E et al (2014) Comparison of short-term infusion regimens of N-acetylcysteine plus intravenous fluids, sodium bicarbonate plus intravenous fluids, and intravenous fluids alone for prevention of contrast-induced nephropathy in the emergency department. Acad Emerg Med 21:615–622PubMedCrossRef Kama A, Yilmaz S, Yaka E et al (2014) Comparison of short-term infusion regimens of N-acetylcysteine plus intravenous fluids, sodium bicarbonate plus intravenous fluids, and intravenous fluids alone for prevention of contrast-induced nephropathy in the emergency department. Acad Emerg Med 21:615–622PubMedCrossRef
75.
go back to reference Briguori C, Visconti G, Focaccio A et al (2011) Renal Insufficiency After Contrast Media Administration Trial II (REMEDIAL II): RenalGuard System in high-risk patients for contrast-induced acute kidney injury. Circulation 124:1260–1269PubMedCrossRef Briguori C, Visconti G, Focaccio A et al (2011) Renal Insufficiency After Contrast Media Administration Trial II (REMEDIAL II): RenalGuard System in high-risk patients for contrast-induced acute kidney injury. Circulation 124:1260–1269PubMedCrossRef
76.
go back to reference Marenzi G, Ferrari C, Marana I et al (2012) Prevention of contrast nephropathy by furosemide with matched hydration: the MYTHOS (Induced Diuresis With Matched Hydration Compared to Standard Hydration for Contrast Induced Nephropathy Prevention) trial. JACC Cardiovasc Interv 5:90–97PubMedCrossRef Marenzi G, Ferrari C, Marana I et al (2012) Prevention of contrast nephropathy by furosemide with matched hydration: the MYTHOS (Induced Diuresis With Matched Hydration Compared to Standard Hydration for Contrast Induced Nephropathy Prevention) trial. JACC Cardiovasc Interv 5:90–97PubMedCrossRef
77.
go back to reference Usmiani T, Andreis A, Budano C et al (2016) AKIGUARD (Acute Kidney Injury GUARding Device) trial: in-hospital and one-year outcomes. J Cardiovasc Med 17:530–537CrossRef Usmiani T, Andreis A, Budano C et al (2016) AKIGUARD (Acute Kidney Injury GUARding Device) trial: in-hospital and one-year outcomes. J Cardiovasc Med 17:530–537CrossRef
78.
go back to reference Brar SS, Aharonian V, Mansukhani P et al (2014) Haemodynamic-guided fluid administration for the prevention of contrast-induced acute kidney injury: the POSEIDON randomised controlled trial. Lancet 383:1814–1823PubMedCrossRef Brar SS, Aharonian V, Mansukhani P et al (2014) Haemodynamic-guided fluid administration for the prevention of contrast-induced acute kidney injury: the POSEIDON randomised controlled trial. Lancet 383:1814–1823PubMedCrossRef
79.
go back to reference Qian G, Fu Z, Guo J, Cao F, Chen Y (2016) Prevention of contrast-induced nephropathy by central venous pressure-guided fluid administration in chronic kidney disease and congestive heart failure patients. JACC Cardiovasc Interv 9:89–96PubMedCrossRef Qian G, Fu Z, Guo J, Cao F, Chen Y (2016) Prevention of contrast-induced nephropathy by central venous pressure-guided fluid administration in chronic kidney disease and congestive heart failure patients. JACC Cardiovasc Interv 9:89–96PubMedCrossRef
80.
go back to reference Aslanger E, Uslu B, Akdeniz C, Polat N, Cizgici Y, Oflaz H (2012) Intrarenal application of N-acetylcysteine for the prevention of contrast medium-induced nephropathy in primary angioplasty. Coron Artery Dis 23:265–270PubMedCrossRef Aslanger E, Uslu B, Akdeniz C, Polat N, Cizgici Y, Oflaz H (2012) Intrarenal application of N-acetylcysteine for the prevention of contrast medium-induced nephropathy in primary angioplasty. Coron Artery Dis 23:265–270PubMedCrossRef
81.
go back to reference Inda-Filho AJ, Caixeta A, Manggini M, Schor N (2014) Do intravenous N-acetylcysteine and sodium bicarbonate prevent high osmolal contrast-induced acute kidney injury? A randomized controlled trial. PLoS One 9:e107602PubMedPubMedCentralCrossRef Inda-Filho AJ, Caixeta A, Manggini M, Schor N (2014) Do intravenous N-acetylcysteine and sodium bicarbonate prevent high osmolal contrast-induced acute kidney injury? A randomized controlled trial. PLoS One 9:e107602PubMedPubMedCentralCrossRef
82.
go back to reference Jaffery Z, Verma A, White CJ et al (2012) A randomized trial of intravenous n-acetylcysteine to prevent contrast induced nephropathy in acute coronary syndromes. Catheter Cardiovasc Interv 79:921–926PubMedCrossRef Jaffery Z, Verma A, White CJ et al (2012) A randomized trial of intravenous n-acetylcysteine to prevent contrast induced nephropathy in acute coronary syndromes. Catheter Cardiovasc Interv 79:921–926PubMedCrossRef
83.
go back to reference O'Sullivan S, Healy DA, Moloney MC, Grace PA, Walsh SR (2013) The role of N-acetylcysteine in the prevention of contrast-induced nephropathy in patients undergoing peripheral angiography: a structured review and meta-analysis. Angiology 64:576–582PubMedCrossRef O'Sullivan S, Healy DA, Moloney MC, Grace PA, Walsh SR (2013) The role of N-acetylcysteine in the prevention of contrast-induced nephropathy in patients undergoing peripheral angiography: a structured review and meta-analysis. Angiology 64:576–582PubMedCrossRef
84.
go back to reference Sun Z, Fu Q, Cao L, Jin W, Cheng L, Li Z (2013) Intravenous N-acetylcysteine for prevention of contrast-induced nephropathy: a meta-analysis of randomized, controlled trials. PLoS One 8:e55124PubMedPubMedCentralCrossRef Sun Z, Fu Q, Cao L, Jin W, Cheng L, Li Z (2013) Intravenous N-acetylcysteine for prevention of contrast-induced nephropathy: a meta-analysis of randomized, controlled trials. PLoS One 8:e55124PubMedPubMedCentralCrossRef
85.
go back to reference Loomba RS, Shah PH, Aggarwal S, Arora RR (2016) Role of N-acetylcysteine to prevent contrast-induced nephropathy: a meta-analysis. Am J Ther 23:e172–e183PubMedCrossRef Loomba RS, Shah PH, Aggarwal S, Arora RR (2016) Role of N-acetylcysteine to prevent contrast-induced nephropathy: a meta-analysis. Am J Ther 23:e172–e183PubMedCrossRef
86.
go back to reference Traub SJ, Mitchell AM, Jones AE et al (2013) N-acetylcysteine plus intravenous fluids versus intravenous fluids alone to prevent contrast-induced nephropathy in emergency computed tomography. Ann Emerg Med 62:511–520PubMedCrossRef Traub SJ, Mitchell AM, Jones AE et al (2013) N-acetylcysteine plus intravenous fluids versus intravenous fluids alone to prevent contrast-induced nephropathy in emergency computed tomography. Ann Emerg Med 62:511–520PubMedCrossRef
87.
go back to reference Poletti PA, Platon A, De Seigneux S et al (2013) N-acetylcysteine does not prevent contrast nephropathy in patients with renal impairment undergoing emergency CT: a randomized study. BMC Nephrol 14:119PubMedPubMedCentralCrossRef Poletti PA, Platon A, De Seigneux S et al (2013) N-acetylcysteine does not prevent contrast nephropathy in patients with renal impairment undergoing emergency CT: a randomized study. BMC Nephrol 14:119PubMedPubMedCentralCrossRef
88.
go back to reference Berwanger O, Cavalcanti AB, Sousa AM et al (2013) Acetylcysteine for the prevention of renal outcomes in patients with diabetes mellitus undergoing coronary and peripheral vascular angiography: a substudy of the acetylcysteine for contrast-induced nephropathy trial. Circ Cardiovasc Interv 6:139–145PubMedCrossRef Berwanger O, Cavalcanti AB, Sousa AM et al (2013) Acetylcysteine for the prevention of renal outcomes in patients with diabetes mellitus undergoing coronary and peripheral vascular angiography: a substudy of the acetylcysteine for contrast-induced nephropathy trial. Circ Cardiovasc Interv 6:139–145PubMedCrossRef
89.
go back to reference Kang X, Hu DY, Li CB, Ai ZS, Peng A (2015) N-acetylcysteine for the prevention of contrast-induced nephropathy in patients with pre-existing renal insufficiency or diabetes: a systematic review and meta-analysis. Ren Fail 37:297–303PubMedCrossRef Kang X, Hu DY, Li CB, Ai ZS, Peng A (2015) N-acetylcysteine for the prevention of contrast-induced nephropathy in patients with pre-existing renal insufficiency or diabetes: a systematic review and meta-analysis. Ren Fail 37:297–303PubMedCrossRef
90.
go back to reference Brown JR, Block CA, Malenka DJ, O'Connor GT, Schoolwerth AC, Thompson CA (2009) Sodium bicarbonate plus N-acetylcysteine prophylaxis: a meta-analysis. JACC Cardiovasc Interv 2:1116–1124PubMedCrossRefPubMedCentral Brown JR, Block CA, Malenka DJ, O'Connor GT, Schoolwerth AC, Thompson CA (2009) Sodium bicarbonate plus N-acetylcysteine prophylaxis: a meta-analysis. JACC Cardiovasc Interv 2:1116–1124PubMedCrossRefPubMedCentral
91.
go back to reference Carbonell N, Blasco M, Sanjuan R et al (2007) Intravenous N-acetylcysteine for preventing contrast-induced nephropathy: a randomised trial. Int J Cardiol 115:57–62PubMedCrossRef Carbonell N, Blasco M, Sanjuan R et al (2007) Intravenous N-acetylcysteine for preventing contrast-induced nephropathy: a randomised trial. Int J Cardiol 115:57–62PubMedCrossRef
92.
go back to reference Heng AE, Cellarier E, Aublet-Cuvelier B et al (2008) Is treatment with N-acetylcysteine to prevent contrast-induced nephropathy when using bicarbonate hydration out of date? Clin Nephrol 70:475–484PubMedCrossRef Heng AE, Cellarier E, Aublet-Cuvelier B et al (2008) Is treatment with N-acetylcysteine to prevent contrast-induced nephropathy when using bicarbonate hydration out of date? Clin Nephrol 70:475–484PubMedCrossRef
93.
go back to reference Staniloae CS, Doucet S, Sharma SK et al (2009) N-Acetylcysteine added to volume expansion with sodium bicarbonate does not further prevent contrast-induced nephropathy: results from the cardiac angiography in renally impaired patients study. J Interv Cardiol 22:261–265PubMedCrossRef Staniloae CS, Doucet S, Sharma SK et al (2009) N-Acetylcysteine added to volume expansion with sodium bicarbonate does not further prevent contrast-induced nephropathy: results from the cardiac angiography in renally impaired patients study. J Interv Cardiol 22:261–265PubMedCrossRef
94.
go back to reference Subramaniam RM, Suarez-Cuervo C, Wilson RF et al (2016) Effectiveness of prevention strategies for contrast-induced nephropathy: a systematic review and meta-analysis. Ann Intern Med 164:406–416PubMedCrossRef Subramaniam RM, Suarez-Cuervo C, Wilson RF et al (2016) Effectiveness of prevention strategies for contrast-induced nephropathy: a systematic review and meta-analysis. Ann Intern Med 164:406–416PubMedCrossRef
95.
go back to reference Ali-Hassan-Sayegh S, Mirhosseini SJ, Ghodratipour Z et al (2017) Strategies preventing contrast-induced nephropathy after coronary angiography: a comprehensive meta-analysis and systematic review of 125 randomized controlled trials. Angiology 68:389–413CrossRef Ali-Hassan-Sayegh S, Mirhosseini SJ, Ghodratipour Z et al (2017) Strategies preventing contrast-induced nephropathy after coronary angiography: a comprehensive meta-analysis and systematic review of 125 randomized controlled trials. Angiology 68:389–413CrossRef
96.
go back to reference Su X, Xie X, Liu L et al (2017) Comparative effectiveness of 12 treatment strategies for preventing contrast-induced acute kidney injury: A systematic review and Bayesian network analysis. Am J Kidney Dis 69:69–77PubMedCrossRef Su X, Xie X, Liu L et al (2017) Comparative effectiveness of 12 treatment strategies for preventing contrast-induced acute kidney injury: A systematic review and Bayesian network analysis. Am J Kidney Dis 69:69–77PubMedCrossRef
97.
go back to reference Briasoulis A, Mallikethi-Reddy S, Sharma S, Briasouli AA, Afonso L (2015) 3-Hydroxy-3-methylglutaryl-CoA reductase enzyme inhibitors for prevention of contrast-induced nephropathy: a meta-analysis of prospective randomized controlled studies. Am J Ther 22:e158–e166PubMedCrossRef Briasoulis A, Mallikethi-Reddy S, Sharma S, Briasouli AA, Afonso L (2015) 3-Hydroxy-3-methylglutaryl-CoA reductase enzyme inhibitors for prevention of contrast-induced nephropathy: a meta-analysis of prospective randomized controlled studies. Am J Ther 22:e158–e166PubMedCrossRef
98.
go back to reference Cheungpasitporn W, Thongprayoon C, Kittanamongkolchai W, et al (2015) Periprocedural effects of statins on the incidence of contrast-induced acute kidney injury: a systematic review and meta-analysis of randomized controlled trials. Ren Fail 37:664–671 Cheungpasitporn W, Thongprayoon C, Kittanamongkolchai W, et al (2015) Periprocedural effects of statins on the incidence of contrast-induced acute kidney injury: a systematic review and meta-analysis of randomized controlled trials. Ren Fail 37:664–671
99.
go back to reference Li H, Wang C, Liu C, Li R, Zou M, Cheng G (2016) Efficacy of short-term statin treatment for the prevention of contrast-induced acute kidney injury in patients undergoing coronary angiography/percutaneous coronary intervention: a meta-analysis of 21 randomized controlled trials. Am J Cardiovasc Drugs 16:201–219PubMedCrossRef Li H, Wang C, Liu C, Li R, Zou M, Cheng G (2016) Efficacy of short-term statin treatment for the prevention of contrast-induced acute kidney injury in patients undergoing coronary angiography/percutaneous coronary intervention: a meta-analysis of 21 randomized controlled trials. Am J Cardiovasc Drugs 16:201–219PubMedCrossRef
100.
go back to reference Liu YH, Liu Y, Duan CY et al (2015) Statins for the prevention of contrast-induced nephropathy after coronary angiography/percutaneous interventions: a meta-analysis of randomized controlled trials. J Cardiovasc Pharmacol Ther 20:181–192PubMedCrossRef Liu YH, Liu Y, Duan CY et al (2015) Statins for the prevention of contrast-induced nephropathy after coronary angiography/percutaneous interventions: a meta-analysis of randomized controlled trials. J Cardiovasc Pharmacol Ther 20:181–192PubMedCrossRef
101.
go back to reference Marenzi G, Cosentino N, Werba JP, Tedesco CC, Veglia F, Bartorelli AL (2015) A meta-analysis of randomized controlled trials on statins for the prevention of contrast-induced acute kidney injury in patients with and without acute coronary syndromes. Int J Cardiol 183:47–53PubMedCrossRef Marenzi G, Cosentino N, Werba JP, Tedesco CC, Veglia F, Bartorelli AL (2015) A meta-analysis of randomized controlled trials on statins for the prevention of contrast-induced acute kidney injury in patients with and without acute coronary syndromes. Int J Cardiol 183:47–53PubMedCrossRef
102.
go back to reference Thompson K, Razi R, Lee MS et al (2016) Statin use prior to angiography for the prevention of contrast-induced acute kidney injury: a meta-analysis of 19 randomised trials. EuroIntervention 12:366–374PubMedCrossRef Thompson K, Razi R, Lee MS et al (2016) Statin use prior to angiography for the prevention of contrast-induced acute kidney injury: a meta-analysis of 19 randomised trials. EuroIntervention 12:366–374PubMedCrossRef
103.
go back to reference Wang N, Qian P, Yan TD, Phan K (2016) Periprocedural effects of statins on the incidence of contrast-induced acute kidney injury: A systematic review and trial sequential analysis. Int J Cardiol 206:143–152PubMedCrossRef Wang N, Qian P, Yan TD, Phan K (2016) Periprocedural effects of statins on the incidence of contrast-induced acute kidney injury: A systematic review and trial sequential analysis. Int J Cardiol 206:143–152PubMedCrossRef
104.
go back to reference Wu H, Li D, Fang M, Han H, Wang H (2015) Meta-analysis of short-term high versus low doses of atorvastatin preventing contrast-induced acute kidney injury in patients undergoing coronary angiography/percutaneous coronary intervention. J Clin Pharmacol 55:123–131PubMedCrossRef Wu H, Li D, Fang M, Han H, Wang H (2015) Meta-analysis of short-term high versus low doses of atorvastatin preventing contrast-induced acute kidney injury in patients undergoing coronary angiography/percutaneous coronary intervention. J Clin Pharmacol 55:123–131PubMedCrossRef
105.
go back to reference Yang Y, Wu YX, Hu YZ (2015) Rosuvastatin treatment for preventing contrast-induced acute kidney injury after cardiac catheterization: a meta-analysis of randomized controlled trials. Medicine 94:e1226PubMedPubMedCentralCrossRef Yang Y, Wu YX, Hu YZ (2015) Rosuvastatin treatment for preventing contrast-induced acute kidney injury after cardiac catheterization: a meta-analysis of randomized controlled trials. Medicine 94:e1226PubMedPubMedCentralCrossRef
106.
go back to reference Vanmassenhove J, Vanholder R, Lameire N (2016) Statins for the prevention of contrast-induced acute kidney injury. Curr Opin Nephrol Hypertens 25:508–517PubMedCrossRef Vanmassenhove J, Vanholder R, Lameire N (2016) Statins for the prevention of contrast-induced acute kidney injury. Curr Opin Nephrol Hypertens 25:508–517PubMedCrossRef
107.
go back to reference Giacoppo D, Capodanno D, Capranzano P, Aruta P, Tamburino C (2014) Meta-analysis of randomized controlled trials of preprocedural statin administration for reducing contrast-induced acute kidney injury in patients undergoing coronary catheterization. Am J Cardiol 114:541–548PubMedCrossRef Giacoppo D, Capodanno D, Capranzano P, Aruta P, Tamburino C (2014) Meta-analysis of randomized controlled trials of preprocedural statin administration for reducing contrast-induced acute kidney injury in patients undergoing coronary catheterization. Am J Cardiol 114:541–548PubMedCrossRef
108.
go back to reference Han Y, Zhu G, Han L et al (2014) Short-term rosuvastatin therapy for prevention of contrast-induced acute kidney injury in patients with diabetes and chronic kidney disease. J Am Coll Cardiol 63:62–70PubMedCrossRef Han Y, Zhu G, Han L et al (2014) Short-term rosuvastatin therapy for prevention of contrast-induced acute kidney injury in patients with diabetes and chronic kidney disease. J Am Coll Cardiol 63:62–70PubMedCrossRef
109.
go back to reference Brueck M, Cengiz H, Hoeltgen R et al (2013) Usefulness of N-acetylcysteine or ascorbic acid versus placebo to prevent contrast-induced acute kidney injury in patients undergoing elective cardiac catheterization: a single-center, prospective, randomized, double-blind, placebo-controlled trial. J Invasive Cardiol 25:276–283PubMed Brueck M, Cengiz H, Hoeltgen R et al (2013) Usefulness of N-acetylcysteine or ascorbic acid versus placebo to prevent contrast-induced acute kidney injury in patients undergoing elective cardiac catheterization: a single-center, prospective, randomized, double-blind, placebo-controlled trial. J Invasive Cardiol 25:276–283PubMed
110.
go back to reference Dvorsak B, Kanic V, Ekart R, Bevc S, Hojs R (2013) Ascorbic acid for the prevention of contrast-induced nephropathy after coronary angiography in patients with chronic renal impairment: a randomized controlled trial. Ther Apher Dial 17:384–390PubMedCrossRef Dvorsak B, Kanic V, Ekart R, Bevc S, Hojs R (2013) Ascorbic acid for the prevention of contrast-induced nephropathy after coronary angiography in patients with chronic renal impairment: a randomized controlled trial. Ther Apher Dial 17:384–390PubMedCrossRef
111.
go back to reference Li R, Chen H (2012) Prevention of contrast-induced nephropathy with ascorbic acid. Heart 98:E211CrossRef Li R, Chen H (2012) Prevention of contrast-induced nephropathy with ascorbic acid. Heart 98:E211CrossRef
112.
go back to reference Albabtain MA, Almasood A, Alshurafah H, Alamri H, Tamim H (2013) Efficacy of ascorbic acid, N-acetylcysteine, or combination of both on top of saline hydration versus saline hydration alone on prevention of contrast-Induced nephropathy: a prospective randomized study. J Interv Cardiol 26:90–96PubMedCrossRef Albabtain MA, Almasood A, Alshurafah H, Alamri H, Tamim H (2013) Efficacy of ascorbic acid, N-acetylcysteine, or combination of both on top of saline hydration versus saline hydration alone on prevention of contrast-Induced nephropathy: a prospective randomized study. J Interv Cardiol 26:90–96PubMedCrossRef
113.
go back to reference Zhou L, Chen H (2012) Prevention of contrast-induced nephropathy with ascorbic acid. Intern Med 51:531–535PubMedCrossRef Zhou L, Chen H (2012) Prevention of contrast-induced nephropathy with ascorbic acid. Intern Med 51:531–535PubMedCrossRef
114.
go back to reference Shakeryan F, Sanati H, Fathi H et al (2013) Evaluation of combination therapy with vitamin C and pentoxifylline on preventing kidney failure secondary to intravenous contrast material in coronary angioplasty. Iran Heart J 14:17–21 Shakeryan F, Sanati H, Fathi H et al (2013) Evaluation of combination therapy with vitamin C and pentoxifylline on preventing kidney failure secondary to intravenous contrast material in coronary angioplasty. Iran Heart J 14:17–21
115.
go back to reference Sadat U, Usman A, Gillard JH, Boyle JR (2013) Does ascorbic acid protect against contrast-induced acute kidney injury in patients undergoing coronary angiography: a systematic review with meta-analysis of randomized, controlled trials. J Am Coll Cardiol 62:2167–2175PubMedCrossRef Sadat U, Usman A, Gillard JH, Boyle JR (2013) Does ascorbic acid protect against contrast-induced acute kidney injury in patients undergoing coronary angiography: a systematic review with meta-analysis of randomized, controlled trials. J Am Coll Cardiol 62:2167–2175PubMedCrossRef
116.
go back to reference Wang XT, Yan J, Li L, Su Q (2014) Anti-oxidative vitamin for the prevention of contrast-induced acute kidney injury in patients with chronic kidney disease: meta-analysis of randomized controlled trials. Exp Clin Cardiol 20:1385–1410 Wang XT, Yan J, Li L, Su Q (2014) Anti-oxidative vitamin for the prevention of contrast-induced acute kidney injury in patients with chronic kidney disease: meta-analysis of randomized controlled trials. Exp Clin Cardiol 20:1385–1410
117.
go back to reference Cruz DN, Perazella MA, Bellomo R et al (2006) Extracorporeal blood purification therapies for prevention of radiocontrast-induced nephropathy: a systematic review. Am J Kidney Dis 48:361–371PubMedCrossRef Cruz DN, Perazella MA, Bellomo R et al (2006) Extracorporeal blood purification therapies for prevention of radiocontrast-induced nephropathy: a systematic review. Am J Kidney Dis 48:361–371PubMedCrossRef
118.
go back to reference Cruz DN, Goh CY, Marenzi G, Corradi V, Ronco C, Perazella MA (2012) Renal replacement therapies for prevention of radiocontrast-induced nephropathy: a systematic review. Am J Med 125:66–78PubMedCrossRef Cruz DN, Goh CY, Marenzi G, Corradi V, Ronco C, Perazella MA (2012) Renal replacement therapies for prevention of radiocontrast-induced nephropathy: a systematic review. Am J Med 125:66–78PubMedCrossRef
119.
go back to reference Song K, Jiang S, Shi Y, Shen H, Shi X, Jing D (2010) Renal replacement therapy for prevention of contrast-induced acute kidney injury: a meta-analysis of randomized controlled trials. Am J Nephrol 32:497–504PubMedCrossRef Song K, Jiang S, Shi Y, Shen H, Shi X, Jing D (2010) Renal replacement therapy for prevention of contrast-induced acute kidney injury: a meta-analysis of randomized controlled trials. Am J Nephrol 32:497–504PubMedCrossRef
120.
go back to reference Reinecke H, Fobker M, Wellmann J et al (2007) A randomized controlled trial comparing hydration therapy to additional hemodialysis or N-acetylcysteine for the prevention of contrast medium-induced nephropathy: the Dialysis-versus-Diuresis (DVD) trial. Clin Res Cardiol 96:130–139PubMedCrossRef Reinecke H, Fobker M, Wellmann J et al (2007) A randomized controlled trial comparing hydration therapy to additional hemodialysis or N-acetylcysteine for the prevention of contrast medium-induced nephropathy: the Dialysis-versus-Diuresis (DVD) trial. Clin Res Cardiol 96:130–139PubMedCrossRef
121.
go back to reference Weisbord SD, Bernardini J, Mor MK et al (2006) The effect of coronary angiography on residual renal function in patients on peritoneal dialysis. Clin Cardiol 29:494–497PubMedCrossRef Weisbord SD, Bernardini J, Mor MK et al (2006) The effect of coronary angiography on residual renal function in patients on peritoneal dialysis. Clin Cardiol 29:494–497PubMedCrossRef
122.
go back to reference Choi MJ, Yoon JW, Han SJ et al (2014) The prevention of contrast-induced nephropathy by simultaneous hemofiltration during coronary angiographic procedures: a comparison with periprocedural hemofiltration. Int J Cardiol 176:941–945PubMedCrossRef Choi MJ, Yoon JW, Han SJ et al (2014) The prevention of contrast-induced nephropathy by simultaneous hemofiltration during coronary angiographic procedures: a comparison with periprocedural hemofiltration. Int J Cardiol 176:941–945PubMedCrossRef
123.
go back to reference Nadkarni GN, Konstantinidis I, Patel A et al (2015) Trimetazidine decreases risk of contrast-induced nephropathy in patients with chronic kidney disease: a meta-analysis of randomized controlled trials. J Cardiovasc Pharmacol Ther 20:539–546PubMedCrossRef Nadkarni GN, Konstantinidis I, Patel A et al (2015) Trimetazidine decreases risk of contrast-induced nephropathy in patients with chronic kidney disease: a meta-analysis of randomized controlled trials. J Cardiovasc Pharmacol Ther 20:539–546PubMedCrossRef
124.
go back to reference Ye Z, Lu H, Su Q et al (2017) Clinical effect of trimetazidine on prevention of contrast-induced nephropathy in patients with renal insufficiency: an updated systematic review and meta-analysis. Medicine 96:e6059PubMedPubMedCentralCrossRef Ye Z, Lu H, Su Q et al (2017) Clinical effect of trimetazidine on prevention of contrast-induced nephropathy in patients with renal insufficiency: an updated systematic review and meta-analysis. Medicine 96:e6059PubMedPubMedCentralCrossRef
125.
go back to reference Bilasy ME, Oraby MA, Ismail HM, Maklady FA (2012) Effectiveness of theophylline in preventing contrast-induced nephropathy after coronary angiographic procedures. J Interv Cardiol 25:404–410PubMedCrossRef Bilasy ME, Oraby MA, Ismail HM, Maklady FA (2012) Effectiveness of theophylline in preventing contrast-induced nephropathy after coronary angiographic procedures. J Interv Cardiol 25:404–410PubMedCrossRef
126.
go back to reference Dai B, Liu Y, Fu L, Li Y, Zhang J, Mei C (2012) Effect of theophylline on prevention of contrast-induced acute kidney injury: a meta-analysis of randomized controlled trials. Am J Kidney Dis 60:360–370PubMedCrossRef Dai B, Liu Y, Fu L, Li Y, Zhang J, Mei C (2012) Effect of theophylline on prevention of contrast-induced acute kidney injury: a meta-analysis of randomized controlled trials. Am J Kidney Dis 60:360–370PubMedCrossRef
127.
go back to reference Matejka J, Varvarovsky I, Vojtisek P et al (2010) Prevention of contrast-induced acute kidney injury by theophylline in elderly patients with chronic kidney disease. Heart Vessels 25:536–542PubMedCrossRef Matejka J, Varvarovsky I, Vojtisek P et al (2010) Prevention of contrast-induced acute kidney injury by theophylline in elderly patients with chronic kidney disease. Heart Vessels 25:536–542PubMedCrossRef
128.
go back to reference Miao Y, Zhong Y, Yan H, Li W, Wang BY, Jin J (2013) Alprostadil plays a protective role in contrast-induced nephropathy in the elderly. Int Urol Nephrol 45:1179–1185PubMedCrossRef Miao Y, Zhong Y, Yan H, Li W, Wang BY, Jin J (2013) Alprostadil plays a protective role in contrast-induced nephropathy in the elderly. Int Urol Nephrol 45:1179–1185PubMedCrossRef
129.
go back to reference Ye Z, Lu H, Guo W et al (2016) The effect of alprostadil on preventing contrast induced nephropathy for percutaneous coronary intervention in diabetic patients: a systematic review and meta-analysis. Medicine 95:e5306PubMedPubMedCentralCrossRef Ye Z, Lu H, Guo W et al (2016) The effect of alprostadil on preventing contrast induced nephropathy for percutaneous coronary intervention in diabetic patients: a systematic review and meta-analysis. Medicine 95:e5306PubMedPubMedCentralCrossRef
130.
go back to reference Thamcharoen N, Thongprayoon C, Edmonds PJ, Cheungpasitporn W (2015) Periprocedural nebivolol for the prevention of contrast-induced acute kidney injury: a systematic review and meta-analysis. N Am J Med Sci 7:446–451PubMedPubMedCentralCrossRef Thamcharoen N, Thongprayoon C, Edmonds PJ, Cheungpasitporn W (2015) Periprocedural nebivolol for the prevention of contrast-induced acute kidney injury: a systematic review and meta-analysis. N Am J Med Sci 7:446–451PubMedPubMedCentralCrossRef
131.
go back to reference Naeem M, McEnteggart GE, Murphy TP, Prince E, Ahn S, Soares G (2015) Fenoldopam for the prevention of contrast-induced nephropathy (CIN) - do we need more trials? A meta-analysis. Clin Imaging 39:759–764PubMedCrossRef Naeem M, McEnteggart GE, Murphy TP, Prince E, Ahn S, Soares G (2015) Fenoldopam for the prevention of contrast-induced nephropathy (CIN) - do we need more trials? A meta-analysis. Clin Imaging 39:759–764PubMedCrossRef
132.
go back to reference Kassis HM, Minsinger KD, McCullough PA, Block CA, Sidhu MS, Brown JR (2015) A review of the use of Iloprost, a synthetic prostacyclin, in the prevention of radiocontrast nephropathy in patients undergoing coronary angiography and intervention. Clin Cardiol 38:492–498PubMedCrossRefPubMedCentral Kassis HM, Minsinger KD, McCullough PA, Block CA, Sidhu MS, Brown JR (2015) A review of the use of Iloprost, a synthetic prostacyclin, in the prevention of radiocontrast nephropathy in patients undergoing coronary angiography and intervention. Clin Cardiol 38:492–498PubMedCrossRefPubMedCentral
133.
go back to reference Inzucchi SE, Bergenstal RM, Buse JB et al (2015) Management of hyperglycemia in type 2 diabetes, 2015: a patient-centered approach: update to a position statement of the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care 38:140–149PubMedCrossRef Inzucchi SE, Bergenstal RM, Buse JB et al (2015) Management of hyperglycemia in type 2 diabetes, 2015: a patient-centered approach: update to a position statement of the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care 38:140–149PubMedCrossRef
134.
go back to reference Inzucchi SE, Lipska KJ, Mayo H, Bailey CJ, McGuire DK (2014) Metformin in patients with type 2 diabetes and kidney disease: a systematic review. JAMA 312:2668–2675PubMedPubMedCentralCrossRef Inzucchi SE, Lipska KJ, Mayo H, Bailey CJ, McGuire DK (2014) Metformin in patients with type 2 diabetes and kidney disease: a systematic review. JAMA 312:2668–2675PubMedPubMedCentralCrossRef
135.
go back to reference Lu WR, Defilippi J, Braun A (2013) Unleash metformin: reconsideration of the contraindication in patients with renal impairment. Ann Pharmacother 47:1488–1497PubMedCrossRef Lu WR, Defilippi J, Braun A (2013) Unleash metformin: reconsideration of the contraindication in patients with renal impairment. Ann Pharmacother 47:1488–1497PubMedCrossRef
136.
go back to reference Richy FF, Sabido-Espin M, Guedes S, Corvino FA, Gottwald-Hostalek U (2014) Incidence of lactic acidosis in patients with type 2 diabetes with and without renal impairment treated with metformin: a retrospective cohort study. Diabetes Care 37:2291–2295PubMedCrossRef Richy FF, Sabido-Espin M, Guedes S, Corvino FA, Gottwald-Hostalek U (2014) Incidence of lactic acidosis in patients with type 2 diabetes with and without renal impairment treated with metformin: a retrospective cohort study. Diabetes Care 37:2291–2295PubMedCrossRef
137.
go back to reference Salpeter SR, Greyber E, Pasternak GA, Salpeter EE (2010) Risk of fatal and nonfatal lactic acidosis with metformin use in type 2 diabetes mellitus. Cochrane Database Syst Rev 14:CD002967 Salpeter SR, Greyber E, Pasternak GA, Salpeter EE (2010) Risk of fatal and nonfatal lactic acidosis with metformin use in type 2 diabetes mellitus. Cochrane Database Syst Rev 14:CD002967
138.
go back to reference Goergen SK, Rumbold G, Compton G, Harris C (2010) Systematic review of current guidelines, and their evidence base, on risk of lactic acidosis after administration of contrast medium for patients receiving metformin. Radiology 254:261–269PubMedCrossRef Goergen SK, Rumbold G, Compton G, Harris C (2010) Systematic review of current guidelines, and their evidence base, on risk of lactic acidosis after administration of contrast medium for patients receiving metformin. Radiology 254:261–269PubMedCrossRef
139.
go back to reference Thomsen HS, Morcos SK, ESUR CMSC (1999) Contrast media and metformin: guidelines to diminish the risk of lactic acidosis in non-insulin-dependent diabetics after administration of contrast media. Eur Radiol 9:738-740 Thomsen HS, Morcos SK, ESUR CMSC (1999) Contrast media and metformin: guidelines to diminish the risk of lactic acidosis in non-insulin-dependent diabetics after administration of contrast media. Eur Radiol 9:738-740
142.
go back to reference Morcos SK, Thomsen HS, Webb JA (2002) Dialysis and contrast media. Eur Radiol 12:3026–3030PubMed Morcos SK, Thomsen HS, Webb JA (2002) Dialysis and contrast media. Eur Radiol 12:3026–3030PubMed
143.
go back to reference Gabutti L (2003) Does continuous venovenous hemodiafiltration concomitant with radiological procedures provide a significant and safe removal of the iodinated contrast ioversol? Blood Purif 21:152–157PubMedCrossRef Gabutti L (2003) Does continuous venovenous hemodiafiltration concomitant with radiological procedures provide a significant and safe removal of the iodinated contrast ioversol? Blood Purif 21:152–157PubMedCrossRef
144.
go back to reference Shinoda T, Hata T, Nakajima K, Yoshimoto H, Niwa A (2002) Time-course of iodine elimination by hemodialysis in patients with renal failure after angiography. Ther Apher 6:437–442PubMedCrossRef Shinoda T, Hata T, Nakajima K, Yoshimoto H, Niwa A (2002) Time-course of iodine elimination by hemodialysis in patients with renal failure after angiography. Ther Apher 6:437–442PubMedCrossRef
145.
go back to reference Younathan CM, Kaude JV, Cook MD, Shaw GS, Peterson JC (1994) Dialysis is not indicated immediately after administration of nonionic contrast agents in patients with end-stage renal disease treated by maintenance dialysis. AJR Am J Roentgenol 163:969–971PubMedCrossRef Younathan CM, Kaude JV, Cook MD, Shaw GS, Peterson JC (1994) Dialysis is not indicated immediately after administration of nonionic contrast agents in patients with end-stage renal disease treated by maintenance dialysis. AJR Am J Roentgenol 163:969–971PubMedCrossRef
Metadata
Title
Post-contrast acute kidney injury. Part 2: risk stratification, role of hydration and other prophylactic measures, patients taking metformin and chronic dialysis patients
Recommendations for updated ESUR Contrast Medium Safety Committee guidelines
Authors
Aart J. van der Molen
Peter Reimer
Ilona A. Dekkers
Georg Bongartz
Marie-France Bellin
Michele Bertolotto
Olivier Clement
Gertraud Heinz-Peer
Fulvio Stacul
Judith A. W. Webb
Henrik S. Thomsen
Publication date
01-07-2018
Publisher
Springer Berlin Heidelberg
Published in
European Radiology / Issue 7/2018
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-017-5247-4

Other articles of this Issue 7/2018

European Radiology 7/2018 Go to the issue