Top

Published in:

01-04-2018 | Computer Applications

Detection of lung carcinoma with predominant ground-glass opacity on CT using temporal subtraction method

Authors: Takashi Terasawa, Takatoshi Aoki, Seiichi Murakami, Hyoungseop Kim, Masami Fujii, Michiko Kobayashi, Chihiro Chihara, Yoshiko Hayashida, Yukunori Korogi

Published in: European Radiology | Issue 4/2018

Abstract

Purpose

To evaluate the usefulness of the CT temporal subtraction (TS) method for the detection of the lung cancer with predominant ground-glass opacity (LC-pGGO).

Materials and methods

Twenty-five pairs of CT and their TS images in patients with LC-pGGO (31 lesions) and 25 pairs of those in patients without nodules were used for an observer performance study. Eight radiologists participated and the statistical significance of differences with and without the CT-TS was assessed by JAFROC analysis.

Results

The average figure-of-merit (FOM) values for all radiologists increased to a statistically significant degree, from 0.861 without CT-TS to 0.912 with CT-TS (p < .001). The average sensitivity for detecting the actionable lesions improved from 73.4 % to 85.9 % using CT-TS. The reading time with CT-TS was not significantly different from that without.

Conclusion

The use of CT-TS improves the observer performance for the detection of LC-pGGO.

Key Points

• CT temporal subtraction can improve the detection accuracy of lung cancer.

• Reading time with temporal subtraction is not different from that without.

• CT temporal subtraction improves observer performance for ground-glass/subsolid nodule detection.

Hansell DM, Bankier AA, MacMahon H, McLoud TC, Müller NL, Remy J (2008) Fleischner Society: glossary of terms for thoracic imaging. Radiology 246:697–722CrossRefPubMed

Travis WD, Travis LB, Devesa SS (1995) Lung cancer. Cancer 75:191–202CrossRefPubMed

Auerbach O, Garfinkel L (1991) The changing pattern of lung carcinoma. Cancer 68:1973–1977CrossRefPubMed

Zwirewich CV, Vedal S, Miller RR, Müller NL (1991) Solitary pulmonary nodules: high-resolution CT and radiologic-pathologic correlation. Radiology 179:469–476CrossRefPubMed

Travis WD, Brambilla E, Noguchi M et al (2011) International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma. J Thorac Oncol 6:244–285CrossRefPubMedPubMedCentral

Travis WD, Brambilla E, Nicholson AG et al (2015) The 2015 world health organization classification of lung tumors: impact of genetic, clinical and radiologic advances since the 2004 classification. J Thorac Oncol 10:1243–1260CrossRefPubMed

Godoy MC, Sabloff B, Naidich DP (2012) Subsolid pulmonary nodules: imaging evaluation and strategic management. Curr Opin Pulm Med 18:304–312CrossRefPubMed

Aoki T, Tomoda Y, Watanabe H et al (2001) Peripheral lung adenocarcinoma: correlation of thin-section CT findings with histologic prognostic factors and survival. Radiology 220:803–809CrossRefPubMed

Kim EA, Johkoh T, Lee KS et al (2001) Quantification of ground-glass opacity on high-resolution CT of small peripheral adenocarcinoma of the lung: pathologic and prognostic implications. Am J Roentgenol 177:1417–1422CrossRef

10.

Aoki T, Nakata H, Watanabe H et al (2000) Evolution of peripheral lung adenocarcinomas: CT findings correlated with histology and tumor doubling time. Am J Roentgenol 174:763–768CrossRef

11.

Hasegawa M, Sone S, Takashima S et al (2000) Growth rate of small lung cancers detected on mass CT screening. Br J Radiol 73:1252–1259CrossRefPubMed

12.

Kobayashi Y, Fukui T, Ito S et al (2013) How long should small lung lesions of ground-glass opacity be followed? J Thorac Oncol 8:309–314CrossRefPubMed

13.

Kano A, Doi K, MacMahon H, Hassell DD, Giger ML (1994) Digital image subtraction of temporally sequential chest images for detection of interval change. Med Phys 21:453–461CrossRefPubMed

14.

Aoki T, Murakami S, Kim H et al (2014) Temporal subtraction method for lung nodule detection on successive thoracic CT soft-copy images. Radiology 271:255–261CrossRefPubMed

15.

Itai Y, Kim H, Ishikawa S, Katsuragawa S, Doi K (2010) Development of a voxel-matching technique for substantial reduction of subtraction artifacts in temporal subtraction images obtained from thoracic MDCT. J Digit Imaging 23:31–38CrossRefPubMed

16.

Chakraborty DP, Berbaum KS (2004) Observer studies involving detection and localization: modeling, analysis, and validation. Med Phys 31:2313–2330CrossRefPubMed

17.

Dorfman DD, Berbaum KS, Metz CE (1992) Receiver operating characteristic rating analysis. Generalization to the population of readers and patients with the jackknife method. Invest Radiol 27:723–731CrossRefPubMed

18.

Naidich DP, Bankier AA, MacMahon H et al (2013) Recommendations for the management of subsolid pulmonary nodules detected at CT: a statement from the Fleischner Society. Radiology 266:304–317CrossRefPubMed

19.

Sawada S, Komori E, Nogami N, Segawa Y, Shinkai T, Yamashita M (2009) Evaluation of lesions corresponding to ground-glass opacities that were resected after computed tomography follow-up examination. Lung Cancer 65:176–179CrossRefPubMed

20.

Henschke CI, Yankelevitz DF, Mirtcheva R et al (2000) CT screening for lung cancer: frequency and significance of part-solid and nonsolid nodules. Am J Roentgenol 178:1053–1057CrossRef

21.

Scholten ET, de Jong PA, de Hoop B et al (2015) Towards a close computed tomography monitoring approach for screen detected subsolid pulmonary nodules? Eur Respir J 45:765–773CrossRefPubMed

Title: Detection of lung carcinoma with predominant ground-glass opacity on CT using temporal subtraction method
Authors: Takashi Terasawa
Takatoshi Aoki
Seiichi Murakami
Hyoungseop Kim
Masami Fujii
Michiko Kobayashi
Chihiro Chihara
Yoshiko Hayashida
Yukunori Korogi
Publication date: 01-04-2018
Publisher: Springer Berlin Heidelberg
Published in: European Radiology / Issue 4/2018
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-017-5085-4

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Detection of lung carcinoma with predominant ground-glass opacity on CT using temporal subtraction method

Abstract

Purpose

Materials and methods

Results

Conclusion

Key Points

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Materials and methods

Results

Conclusion

Key Points

Please log in to get access to this content

Other articles of this Issue 4/2018

CT texture features of liver parenchyma for predicting development of metastatic disease and overall survival in patients with colorectal cancer

Correlation between the availability of dopamine transporter and olfactory function in healthy subjects

MRI features of primary rare malignancies of the liver: A report from four university centres

Radiologist involvement is associated with reduced use of MRI in the acute period of low back pain in a non-elderly population

Assessment of micro-dose biplanar radiography in lower limb measurements in children

Chemoembolisation for hepatocellular carcinoma with bile duct invasion: is preprocedural biliary drainage mandatory?