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European Radiology
Published in: European Radiology 1/2018

01-01-2018 | Magnetic Resonance

Left ventricular regional myocardial motion and twist function in repaired tetralogy of Fallot evaluated by magnetic resonance tissue phase mapping

Authors: Meng-Chu Chang, Ming-Ting Wu, Ken-Pen Weng, Mao-Yuan Su, Marius Menza, Hung-Chieh Huang, Hsu-Hsia Peng

Published in: European Radiology | Issue 1/2018

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Abstract

Objectives

We aimed to characterise regional myocardial motion and twist function in the left ventricles (LV) in patients with repaired tetralogy of Fallot (rTOF) and preserved LV global function.

Methods

We recruited 47 rTOF patients and 38 age-matched normal volunteers. Tissue phase mapping (TPM) was performed for evaluating the LV myocardial velocity in longitudinal, radial, and circumferential (Vz, Vr, and VØ) directions in basal, middle, and apical slices. The VØ peak-to-peak (PTP) during systolic phases, the rotation angle of each slice, and VØ inconsistency were computed for evaluating LV twist function and VØ dyssynchrony.

Results

As compared to the controls, the rTOF patients presented decreased RV ejection fraction (RVEF) (p = 0.002) and preserved global LV ejection fraction (LVEF). They also demonstrated decreased systolic and diastolic Vz in several LV segments and higher diastolic Vr in the septum (all p < 0.05). A lower VØ PTP, higher VØ inconsistency, and reduced peak net rotation angle (all p < 0.05) were observed. The aforementioned indices demonstrated an altered LV twist function in rTOF patients in an early disease stage.

Conclusions

MR TPM could provide information about early abnormalities of LV regional motion and twist function in rTOF patients with preserved LV global function.

Key points

• Patients with rTOF presented significantly reduced systolic and diastolic Vz in the LV.
• rTOF patients demonstrated significantly increased diastolic Vr in the septum.
• Abnormal characteristics of the segmental dynamic velocity evolution were shown in rTOF.
• rTOF patients presented altered circumferential rotation and velocity inconsistency in early stage.
Appendix
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Metadata
Title
Left ventricular regional myocardial motion and twist function in repaired tetralogy of Fallot evaluated by magnetic resonance tissue phase mapping
Authors
Meng-Chu Chang
Ming-Ting Wu
Ken-Pen Weng
Mao-Yuan Su
Marius Menza
Hung-Chieh Huang
Hsu-Hsia Peng
Publication date
01-01-2018
Publisher
Springer Berlin Heidelberg
Published in
European Radiology / Issue 1/2018
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-017-4908-7

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