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European Radiology
Published in: European Radiology 6/2017

01-06-2017 | Magnetic Resonance

Increased susceptibility of asymmetrically prominent cortical veins correlates with misery perfusion in patients with occlusion of the middle cerebral artery

Authors: Yu Luo, Zhongying Gong, Yongming Zhou, Binge Chang, Chao Chai, Taiyuan Liu, Yanhong Han, Meiyun Wang, Tianyi Qian, E Mark Haacke, Shuang Xia

Published in: European Radiology | Issue 6/2017

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Abstract

Objectives

To evaluate tissue perfusion and venous susceptibility in ischaemic stroke patients as a means to predict clinical status and early prognosis.

Methods

A retrospective study of 51 ischaemic stroke patients were enrolled in this study. Susceptibility, perfusion and National Institute of Health stroke scale (NIHSS) were compared between patients with and without asymmetrically prominent cortical veins (APCVs). The correlation between susceptibility, perfusion and NIHSS was performed.

Results

Compared to patients without APCVs, the age of patients with APCVs was statistically older (p = 0.017). Patients with APCVs at discharge showed clinical deterioration in their NIHSS. Mean transit time (MTT), time to peak (TTP) and cerebral blood flow (CBF) in the stroke hemisphere were statistically delayed/decreased in patients with and without APCVs (all p < 0.05). In patients with APCVs, the changes in susceptibility positively correlated with increases in MTT and TTP (p < 0.05). Susceptibility and TTP positively correlated and CBF negatively correlated with NIHSS both at admission and discharge (p < 0.05).

Conclusions

Patients with APCVs have a tendency of deterioration. The presence of APCVs indicates the tissue has increased oxygen extraction fraction. Increased susceptibility from APCVs positively correlated with the delayed MTT and TTP, which reflects the clinical status at admission and predicts an early prognosis.

Key points

• Patients with and without APCVs have similar misery perfusion.
• Patients with APCVs have a tendency of deterioration compared to those without.
• The presence of APCVs indicated the tissue has increased oxygen extraction fraction.
• Increased susceptibility from APCVs positively correlated with the MTT and TTP.
• Increased susceptibility from APCVs reflected the clinical status at admission.
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Metadata
Title
Increased susceptibility of asymmetrically prominent cortical veins correlates with misery perfusion in patients with occlusion of the middle cerebral artery
Authors
Yu Luo
Zhongying Gong
Yongming Zhou
Binge Chang
Chao Chai
Taiyuan Liu
Yanhong Han
Meiyun Wang
Tianyi Qian
E Mark Haacke
Shuang Xia
Publication date
01-06-2017
Publisher
Springer Berlin Heidelberg
Published in
European Radiology / Issue 6/2017
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-016-4593-y

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