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European Radiology
Published in: European Radiology 5/2015

01-05-2015 | Interventional

Preliminary clinical experience with a dedicated interventional robotic system for CT-guided biopsies of lung lesions: a comparison with the conventional manual technique

Authors: Michele Anzidei, Renato Argirò, Andrea Porfiri, Fabrizio Boni, Marco Anile, Fulvio Zaccagna, Domenico Vitolo, Luca Saba, Alessandro Napoli, Andrea Leonardi, Flavia Longo, Federico Venuta, Mario Bezzi, Carlo Catalano

Published in: European Radiology | Issue 5/2015

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Abstract

Objective

Evaluate the performance of a robotic system for CT-guided lung biopsy in comparison to the conventional manual technique.

Materials and methods

One hundred patients referred for CT-guided lung biopsy were randomly assigned to group A (robot-assisted procedure) or group B (conventional procedure). Size, distance from entry point and position in lung of target lesions were evaluated to assess homogeneity differences between the two groups. Procedure duration, dose length product (DLP), precision of needle positioning, diagnostic performance of the biopsy and rate of complications were evaluated to assess the clinical performance of the robotic system as compared to the conventional technique.

Results

All biopsies were successfully performed. The size (p = 0.41), distance from entry point (p = 0.86) and position in lung (p = 0.32) of target lesions were similar in both groups (p = 0.05). Procedure duration and radiation dose were significantly reduced in group A as compared to group B (p = 0.001). Precision of needle positioning, diagnostic performance of the biopsy and rate of complications were similar in both groups (p = 0.05).

Conclusion

Robot-assisted CT-guided lung biopsy can be performed safely and with high diagnostic accuracy, reducing procedure duration and radiation dose in comparison to the conventional manual technique.

Key Points

• CT-guided biopsy is the main procedure to obtain diagnosis in lung tumours.
• The robotic device facilitates percutaneous needle placement under CT guidance.
• Robot-assisted CT-guided lung biopsy reduces procedure duration and radiation dose.
Literature
1.
MacMahon H, Austin JH, Gamsu G, Herold CJ, Jett JR, Naidich DP, Patz EF Jr, Swensen SJ, Fleischner Society (2005) Guidelines for management of small pulmonary nodules detected on CT scans: a statement from the Fleischner Society. Radiology 237:395–400CrossRefPubMed
2.
Naidich DP, Bankier AA, MacMahon H, Schaefer-Prokop CM, Pistolesi M, Goo JM, Macchiarini P, Crapo JD, Herold CJ, Austin JH, Travis WD (2013) Recommendations for the management of subsolid pulmonari nodules detected at CT: a statement from the Fleischner Society. Radiology 266:304–317CrossRefPubMed
3.
Gould MK, Donington J, Lynch WR, Mazzone PJ, Midthun DE, Naidich DP, Wiener RS (2013) Evaluation of individuals with pulmonary nodules: when is it lung cancer? Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines. Chest 143:e93S–e120SCrossRefPubMedCentralPubMed
4.
Tuna T, Ozkaya S, Dirican A, Findik S, Atici AG, Erkan L (2013) Diagnostic efficacy of computed tomography-guided transthoracic needle aspiration and biopsy in patients with pulmonary disease. Onco Targets Ther 6:1553–1557PubMedCentralPubMed
5.
6.
Kim GR, Hur J, Lee SM, Lee HJ, Hong YJ, Nam JE, Kim HS, Kim YJ, Choi BW, Kim TH, Choe KO (2011) CT fluoroscopy-guided lung biopsy versus conventional CT-guided lung biopsy: a prospective controlled study to assess radiation doses and diagnostic performance. Eur Radiol 21:232–239CrossRefPubMed
7.
Prosch H, Stadler A, Schilling M, Bürklin S, Eisenhuber E, Schober E, Mostbeck G (2012) CT fluoroscopy-guided vs. multislice CT biopsy mode-guided lung biopsies: accuracy, complications and radiation dose. Eur J Radiol 81:1029–1033CrossRefPubMed
8.
9.
Grasso RF, Faiella E, Luppi G, Schena E, Giurazza F, Del Vescovo R, D'Agostino F, Cazzato RL, Beomonte Zobel B (2013) Percutaneous lung biopsy: comparison between an augmented reality CT navigation system and standard CT-guided technique. Int J Comput Assist Radiol Surg 8:837–848CrossRefPubMed
10.
Kettenbach J, Kronreif G, Melzer A, Fichtinger G, Stoianovici D, Cleary K (2007) Ultrasound-, CT- and MR-guided robot-assisted interventions. In: Neri E, Caramella D, Bartolozzi C (eds) Image processing in radiology: current applications. Springer, Heidelberg, pp 391–404
11.
Koethe Y, Xu S, Velusamy G, Wood BJ, Venkatesan AM (2014) Accuracy and efficacy of percutaneous biopsy and ablation using robotic assistance under computed tomography guidance: a phantom study. Eur Radiol 24(3):723–730
12.
Abdullah BJ, Yeong CH, Goh KL, Yoong BK, Ho GF, Yim CC, Kulkarni A (2014) Robot-assisted radiofrequency ablation of primary and secondary liver tumours: early experience. Eur Radiol 24:79–85CrossRefPubMedCentralPubMed
13.
Sacks D, McClenny TE, Cardella JF, Lewis CA (2003) Society of Interventional Radiology clinical practice guidelines. J Vasc Interv Radiol 14:S199–S202CrossRefPubMed
14.
von Jako CR, Zuk Y, Zur O, Gilboa P (2013) A novel accurate minioptical tracking system for percutaneous needle placement. IEEE Trans Biomed Eng 60:2222–2225CrossRef
15.
Krücker J, Xu S, Glossop N, Viswanathan A, Borgert J, Schulz H, Wood BJ (2007) Electromagnetic tracking for thermal ablation and biopsy guidance: clinical evaluation of spatial accuracy. J Vasc Interv Radiol 18:1141–1150CrossRefPubMedCentralPubMed
16.
Tovar-Arriaga S, Tita R, Pedraza-Ortega JC, Gorrostieta E, Kalender WA (2011) Development of a robotic FD-CT-guided navigation system for needle placement-preliminary accuracy tests. Int J Med Robot 7:225–236CrossRefPubMed
17.
Yanof J, Haaga J, Klahr P (2001) CT-integrated robot for interventional procedures: preliminary experiment and computer human interfaces. Comput Aided Surg 6:352–359CrossRefPubMed
18.
Schulz B, Eichler K, Siebenhandl P et al (2012) Accuracy and speed of robotic assisted needle interventions using a modern cone beam computed tomography intervention suite: a phantom study. Eur Radiol 23:198–204CrossRefPubMed
19.
Su L-M, Stoianovici D, Jarrett TW et al (2002) Robotic percutaneous access to the kidney: comparison with standard manual access. J Endourol 16:471–475CrossRefPubMed
Metadata
Title
Preliminary clinical experience with a dedicated interventional robotic system for CT-guided biopsies of lung lesions: a comparison with the conventional manual technique
Authors
Michele Anzidei
Renato Argirò
Andrea Porfiri
Fabrizio Boni
Marco Anile
Fulvio Zaccagna
Domenico Vitolo
Luca Saba
Alessandro Napoli
Andrea Leonardi
Flavia Longo
Federico Venuta
Mario Bezzi
Carlo Catalano
Publication date
01-05-2015
Publisher
Springer Berlin Heidelberg
Published in
European Radiology / Issue 5/2015
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-014-3508-z

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