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Published in: European Radiology 8/2013

01-08-2013 | Magnetic Resonance

CEM43°C thermal dose thresholds: a potential guide for magnetic resonance radiofrequency exposure levels?

Authors: Gerard C. van Rhoon, Theodoros Samaras, Pavel S. Yarmolenko, Mark W. Dewhirst, Esra Neufeld, Niels Kuster

Published in: European Radiology | Issue 8/2013

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Abstract

Objective

To define thresholds of safe local temperature increases for MR equipment that exposes patients to radiofrequency fields of high intensities for long duration. These MR systems induce heterogeneous energy absorption patterns inside the body and can create localised hotspots with a risk of overheating.

Methods

The MRI + EUREKA research consortium organised a “Thermal Workshop on RF Hotspots”. The available literature on thresholds for thermal damage and the validity of the thermal dose (TD) model were discussed.

Results/Conclusions

The following global TD threshold guidelines for safe use of MR are proposed:
1.
All persons: maximum local temperature of any tissue limited to 39 °C
 
2.
Persons with compromised thermoregulation AND
(a)
Uncontrolled conditions: maximum local temperature limited to 39 °C
 
(b)
Controlled conditions: TD < 2 CEM43°C
 
 
3.
Persons with uncompromised thermoregulation AND
(a)
Uncontrolled conditions: TD < 2 CEM43°C
 
(b)
Controlled conditions: TD < 9 CEM43°C
 
 
The following definitions are applied:
Controlled conditions
A medical doctor or a dedicated trained person can respond instantly to heat-induced physiological stress
Compromised thermoregulation
All persons with impaired systemic or reduced local thermoregulation

Key Points

Standard MRI can cause local heating by radiofrequency absorption.
Monitoring thermal dose (in units of CEM43°C) can control risk during MRI.
9 CEM43°C seems an acceptable thermal dose threshold for most patients.
For skin, muscle, fat and bone,16 CEM43°C is likely acceptable.
Appendix
Available only for authorised users
Footnotes
1
This workshop was co-sponsored by the Mobile Manufacturers Forum, the GSM Association, and the US Food and Drug Administration. A selection of the presentations are published in the Special Issue entitled “Thermal Aspects of Radio Frequency Exposure on Human Health”; Int. J. Hyperthermia; 4, 2011. Guest Editor: Joseph Morrissey.
 
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Metadata
Title
CEM43°C thermal dose thresholds: a potential guide for magnetic resonance radiofrequency exposure levels?
Authors
Gerard C. van Rhoon
Theodoros Samaras
Pavel S. Yarmolenko
Mark W. Dewhirst
Esra Neufeld
Niels Kuster
Publication date
01-08-2013
Publisher
Springer Berlin Heidelberg
Published in
European Radiology / Issue 8/2013
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-013-2825-y

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