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Published in: European Radiology 2/2012

01-02-2012 | Computed Tomography

Comparison of image quality and radiation dose of different pulmonary CTA protocols on a 128-slice CT: high-pitch dual source CT, dual energy CT and conventional spiral CT

Authors: Tobias De Zordo, Klemens von Lutterotti, Christian Dejaco, Peter F. Soegner, Renate Frank, Friedrich Aigner, Andrea S. Klauser, Christoph Pechlaner, U. Joseph Schoepf, Werner R. Jaschke, Gudrun M. Feuchtner

Published in: European Radiology | Issue 2/2012

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Abstract

Objectives

To compare image quality and radiation dose of high-pitch dual-source computed tomography (DSCT), dual energy CT (DECT) and conventional single-source spiral CT (SCT) for pulmonary CT angiography (CTA) on a 128-slice CT system.

Methods

Pulmonary CTA was performed with five protocols: high-pitch DSCT (100 kV), high-pitch DSCT (120 kV), DECT (100/140 kV), SCT (100 kV), and SCT (120 kV). For each protocol, 30 sex, age, and body-mass-index (mean 25.3 kg/m2) matched patients were identified. Retrospectively, two observers subjectively assessed image quality, measured CT attenuation (HU±SD) at seven central and peripheral levels, and calculated signal-to-noise-ratio (SNR) and contrast-to-noise-ratio (CNR). Radiation exposure parameters (CTDIvol and DLP) were compared.

Results

Subjective image quality was rated good to excellent in >92% (>138/150) with an interobserver agreement of 91.4%. The five protocols did not significantly differ in image quality, neither by subjective, nor by objective measures (SNR, CNR). By contrast, radiation exposure differed between protocols: significant lower radiation was achieved by using high-pitch DSCT at 100 kV (p < 0.01 in all). Radiation exposure of DECT was in between SCT at 100 kV and 120 kV.

Conclusions

SCT, high-pitch DSCT, and DECT protocols techniques result in similar subjective and objective image quality, but radiation exposure was significantly lower with high-pitch DSCT at 100 kV.

Key Points

  • New CT protocols show promising results in pulmonary embolism assessment.
  • High-pitch dual-source CT (DSCT) at 100 kV provides radiation dose savings for pulmonary CTA.
  • High-pitch DSCT at 100 kV maintains diagnostic image quality for pulmonary CTA.
  • Dual energy CT uses more radiation but also provides lung perfusion evaluation.
  • Whether the additional perfusion data is worth the extra radiation remains undetermined.
Literature
1.
go back to reference Remy-Jardin M, Pistolesi M, Goodman LR, Gefter WB, Gottschalk A, Mayo JR, Sostman HD (2007) Management of suspected acute pulmonary embolism in the era of CT angiography: a statement from the Fleischner Society. Radiology 245:315–329PubMedCrossRef Remy-Jardin M, Pistolesi M, Goodman LR, Gefter WB, Gottschalk A, Mayo JR, Sostman HD (2007) Management of suspected acute pulmonary embolism in the era of CT angiography: a statement from the Fleischner Society. Radiology 245:315–329PubMedCrossRef
2.
go back to reference Qanadli SD, Hajjam ME, Mesurolle B et al (2000) Pulmonary embolism detection: prospective evaluation of dual-section helical CT versus selective pulmonary arteriography in 157 patients. Radiology 217:447–455PubMed Qanadli SD, Hajjam ME, Mesurolle B et al (2000) Pulmonary embolism detection: prospective evaluation of dual-section helical CT versus selective pulmonary arteriography in 157 patients. Radiology 217:447–455PubMed
3.
go back to reference Winer-Muram HT, Rydberg J, Johnson MS et al (2004) Suspected acute pulmonary embolism: evaluation with multi-detector row CT versus digital subtraction pulmonary arteriography. Radiology 233:806–815PubMedCrossRef Winer-Muram HT, Rydberg J, Johnson MS et al (2004) Suspected acute pulmonary embolism: evaluation with multi-detector row CT versus digital subtraction pulmonary arteriography. Radiology 233:806–815PubMedCrossRef
4.
go back to reference Stein PD, Fowler SE, Goodman LR et al (2006) Multidetector computed tomography for acute pulmonary embolism. N Engl J Med 354:2317–2327PubMedCrossRef Stein PD, Fowler SE, Goodman LR et al (2006) Multidetector computed tomography for acute pulmonary embolism. N Engl J Med 354:2317–2327PubMedCrossRef
5.
go back to reference Flohr TG, Bruder H, Stierstorfer K et al (2008) Image reconstruction and image quality evaluation for a dual source CT scanner. Med Phys 35:5882–5897PubMedCrossRef Flohr TG, Bruder H, Stierstorfer K et al (2008) Image reconstruction and image quality evaluation for a dual source CT scanner. Med Phys 35:5882–5897PubMedCrossRef
6.
go back to reference Petersilka M, Bruder H, Krauss B et al (2008) Technical principles of dual source CT. Eur J Radiol 68:362–368PubMedCrossRef Petersilka M, Bruder H, Krauss B et al (2008) Technical principles of dual source CT. Eur J Radiol 68:362–368PubMedCrossRef
7.
go back to reference Sommer WH, Schenzle JC, Becker CR, Nikolaou K, Graser A, Michalski G, Neumaier K, Reiser MF, Johnson TR (2010) Saving dose in triple-rule-out computed tomography examination using a high-pitch dual spiral technique. Invest Radiol 45:64–71PubMedCrossRef Sommer WH, Schenzle JC, Becker CR, Nikolaou K, Graser A, Michalski G, Neumaier K, Reiser MF, Johnson TR (2010) Saving dose in triple-rule-out computed tomography examination using a high-pitch dual spiral technique. Invest Radiol 45:64–71PubMedCrossRef
8.
go back to reference Johnson TRC, Krauss B, Sedlmair M et al (2007) Material differentiation by dual energy CT: initial experience. Eur Radiol 17:1510–1517PubMedCrossRef Johnson TRC, Krauss B, Sedlmair M et al (2007) Material differentiation by dual energy CT: initial experience. Eur Radiol 17:1510–1517PubMedCrossRef
9.
go back to reference Ferda J, Flohr T, Kreuzberg B (2008) Tissue imaging with dual-energy computed tomography—initial clinical experience. Ces Radiol 62:11–22 Ferda J, Flohr T, Kreuzberg B (2008) Tissue imaging with dual-energy computed tomography—initial clinical experience. Ces Radiol 62:11–22
10.
go back to reference Fink C, Johnson TR, Michaely HJ et al (2008) Dual-energy CT angiography of the lung in patients with suspected pulmonary embolism: initial results. Rofo 180:879–883PubMed Fink C, Johnson TR, Michaely HJ et al (2008) Dual-energy CT angiography of the lung in patients with suspected pulmonary embolism: initial results. Rofo 180:879–883PubMed
11.
go back to reference Pontana F, Faivre JB, Remy-Jardin M et al (2008) Lung perfusion with dual-energy multidetector-row CT (MDCT): feasibility for the evaluation of acute pulmonary embolism in 117 consecutive patients. Acad Radiol 15:1494–1504PubMedCrossRef Pontana F, Faivre JB, Remy-Jardin M et al (2008) Lung perfusion with dual-energy multidetector-row CT (MDCT): feasibility for the evaluation of acute pulmonary embolism in 117 consecutive patients. Acad Radiol 15:1494–1504PubMedCrossRef
12.
go back to reference Thieme SF, Becker CR, Hacker M, Nikolaou K, Reiser MF, Johnson TR (2008) Dual energy CT for the assessment of lung perfusion–correlation to scintigraphy. Eur J Radiol 68:369–374PubMedCrossRef Thieme SF, Becker CR, Hacker M, Nikolaou K, Reiser MF, Johnson TR (2008) Dual energy CT for the assessment of lung perfusion–correlation to scintigraphy. Eur J Radiol 68:369–374PubMedCrossRef
13.
go back to reference Hoey ET, Gopalan D, Ganesh V et al (2009) Dual-energy CT pulmonary angiography: a novel technique for assessing acute and chronic pulmonary thromboembolism. Clin Radiol 64:414–419PubMedCrossRef Hoey ET, Gopalan D, Ganesh V et al (2009) Dual-energy CT pulmonary angiography: a novel technique for assessing acute and chronic pulmonary thromboembolism. Clin Radiol 64:414–419PubMedCrossRef
14.
go back to reference Chae EJ, Seo JB, Jang YM, Krauss B, Lee CW, Lee HJ, Song KS (2010) Dual-energy CT for assessment of the severity of acute pulmonary embolism: pulmonary perfusion defect score compared with CT angiographic obstruction score and right ventricular/left ventricular diameter ratio. AJR Am J Roentgenol 194:604–610PubMedCrossRef Chae EJ, Seo JB, Jang YM, Krauss B, Lee CW, Lee HJ, Song KS (2010) Dual-energy CT for assessment of the severity of acute pulmonary embolism: pulmonary perfusion defect score compared with CT angiographic obstruction score and right ventricular/left ventricular diameter ratio. AJR Am J Roentgenol 194:604–610PubMedCrossRef
15.
go back to reference Primak AN, Giraldo JCR, Eusemann CD, Schmidt B, Kantor B, Fletcher JG, McCollough CH (2010) Dual-source dual-energy CT with additional tin filtration: dose and image quality evaluation in phantoms and in vivo. AJR Am J Roentgenol 195:1164–1174PubMedCrossRef Primak AN, Giraldo JCR, Eusemann CD, Schmidt B, Kantor B, Fletcher JG, McCollough CH (2010) Dual-source dual-energy CT with additional tin filtration: dose and image quality evaluation in phantoms and in vivo. AJR Am J Roentgenol 195:1164–1174PubMedCrossRef
16.
go back to reference International Commission on Radiological Protection and Measurements. Radiological protection and safety. International Commission on Radiological Protection Measurements publication no. 60. Oxford, England: Pergamon, 1991 International Commission on Radiological Protection and Measurements. Radiological protection and safety. International Commission on Radiological Protection Measurements publication no. 60. Oxford, England: Pergamon, 1991
17.
go back to reference Chae EJ, Song JW, Seo JB, Krauss B, Jang YM, Song KS (2008) Clinical utility of dual-energy CT in the evaluation of solitary pulmonary nodules: initial experience. Radiology 249:671–681PubMedCrossRef Chae EJ, Song JW, Seo JB, Krauss B, Jang YM, Song KS (2008) Clinical utility of dual-energy CT in the evaluation of solitary pulmonary nodules: initial experience. Radiology 249:671–681PubMedCrossRef
18.
go back to reference Flohr TG, Leng S, Yu L et al (2009) Dual-source spiral CT with pitch up to 3.2 and 75 ms temporal resolution: image reconstruction and assessment of image quality. Med Phys 36:5641–5653PubMedCrossRef Flohr TG, Leng S, Yu L et al (2009) Dual-source spiral CT with pitch up to 3.2 and 75 ms temporal resolution: image reconstruction and assessment of image quality. Med Phys 36:5641–5653PubMedCrossRef
19.
go back to reference Kristiansson M, Holmquist F, Nyman U (2010) Ultralow contrast medium doses at CT to diagnose pulmonary embolism in patients with moderate to severe renal impairment: a feasibility study. Eur Radiol 20:1321–1330PubMedCrossRef Kristiansson M, Holmquist F, Nyman U (2010) Ultralow contrast medium doses at CT to diagnose pulmonary embolism in patients with moderate to severe renal impairment: a feasibility study. Eur Radiol 20:1321–1330PubMedCrossRef
20.
go back to reference Schoellnast H, Deutschmann HA, Fritz GA, Stessel U, Schaffler GJ, Tillich M (2005) MDCT angiography of the pulmonary arteries: influence of iodine flow concentration on vessel attenuation and visualization. AJR Am J Roentgenol 184:1935–1939PubMed Schoellnast H, Deutschmann HA, Fritz GA, Stessel U, Schaffler GJ, Tillich M (2005) MDCT angiography of the pulmonary arteries: influence of iodine flow concentration on vessel attenuation and visualization. AJR Am J Roentgenol 184:1935–1939PubMed
21.
go back to reference Ghaye B, Szapiro D, Mastora I et al (2001) Peripheral pulmonary arteries: how far does multidetector–row spiral CT allow analysis? Radiology 219:629–636PubMed Ghaye B, Szapiro D, Mastora I et al (2001) Peripheral pulmonary arteries: how far does multidetector–row spiral CT allow analysis? Radiology 219:629–636PubMed
22.
go back to reference Schoepf UJ, Goldhaber SZ, Costello P (2004) Spiral computed tomography for acute pulmonary embolism. Circulation 109:2160–2167PubMedCrossRef Schoepf UJ, Goldhaber SZ, Costello P (2004) Spiral computed tomography for acute pulmonary embolism. Circulation 109:2160–2167PubMedCrossRef
23.
go back to reference Coche E, Verschuren F, Keyeux A et al (2003) Diagnosis of acute pulmonary embolism in outpatients: comparison of thin-collimation multi– detector row spiral CT and planar ventilation-perfusion scintigraphy. Radiology 229:757–765PubMedCrossRef Coche E, Verschuren F, Keyeux A et al (2003) Diagnosis of acute pulmonary embolism in outpatients: comparison of thin-collimation multi– detector row spiral CT and planar ventilation-perfusion scintigraphy. Radiology 229:757–765PubMedCrossRef
24.
go back to reference Raptopoulos V, Boiselle PM (2001) Multi–detector row spiral CT pulmonary angiography: comparison with single–detector row spiral CT. Radiology 221:606–613PubMedCrossRef Raptopoulos V, Boiselle PM (2001) Multi–detector row spiral CT pulmonary angiography: comparison with single–detector row spiral CT. Radiology 221:606–613PubMedCrossRef
25.
go back to reference Schoepf UJ, Holzknecht N, Helmberger TK et al (2002) Subsegmental pulmonary emboli: improved detection with thin-collimation multi– detector row spiral CT. Radiology 222:483–490PubMedCrossRef Schoepf UJ, Holzknecht N, Helmberger TK et al (2002) Subsegmental pulmonary emboli: improved detection with thin-collimation multi– detector row spiral CT. Radiology 222:483–490PubMedCrossRef
26.
go back to reference Patel S, Kazerooni EA, Cascade PN (2003) Pulmonary embolism: optimization of small pulmonary artery visualization at multi– detector row CT. Radiology 227:455–460PubMedCrossRef Patel S, Kazerooni EA, Cascade PN (2003) Pulmonary embolism: optimization of small pulmonary artery visualization at multi– detector row CT. Radiology 227:455–460PubMedCrossRef
27.
go back to reference Brunot S, Corneloup O, Latrabe V, Montaudon M, Laurent F (2005) Reproducibility of multidetector spiral computed tomography in detection of subsegmental acute pulmonary embolism. Eur Radiol 15:2057–2063PubMedCrossRef Brunot S, Corneloup O, Latrabe V, Montaudon M, Laurent F (2005) Reproducibility of multidetector spiral computed tomography in detection of subsegmental acute pulmonary embolism. Eur Radiol 15:2057–2063PubMedCrossRef
28.
go back to reference Schertler T, Scheffel H, Frauenfelder T, Desbiolles L, Leschka S, Stolzmann P, Seifert B, Flohr TG, Marincek B, Alkadhi H (2007) Dual-source computed tomography in patients with acute chest pain: feasibility and image quality. Eur Radiol 17:3179–3188PubMedCrossRef Schertler T, Scheffel H, Frauenfelder T, Desbiolles L, Leschka S, Stolzmann P, Seifert B, Flohr TG, Marincek B, Alkadhi H (2007) Dual-source computed tomography in patients with acute chest pain: feasibility and image quality. Eur Radiol 17:3179–3188PubMedCrossRef
29.
go back to reference Valentin J (2007) The 2007 recommendations of the International Commission on Radiological Protection. ICRP publication 103. Ann ICRP 37:1–332 Valentin J (2007) The 2007 recommendations of the International Commission on Radiological Protection. ICRP publication 103. Ann ICRP 37:1–332
30.
go back to reference Schenzle JC, Sommer WH, Neumaier K, Michalski G, Lechel U, Nikolaou K, Becker CR, Reiser MF, Johnson TR (2010) Dual energy CT of the chest: how about the dose? Invest Radiol 45:347–353PubMed Schenzle JC, Sommer WH, Neumaier K, Michalski G, Lechel U, Nikolaou K, Becker CR, Reiser MF, Johnson TR (2010) Dual energy CT of the chest: how about the dose? Invest Radiol 45:347–353PubMed
31.
go back to reference Bauer RW, Kramer S, Renker M, Schell B, Larson MC, Beeres M, Lehnert T, Jacobi V, Vogl TJ, Kerl JM (2011) Dose and image quality at CT pulmonary angiography-comparison of first and second generation dual-energy CT and 64-slice CT. Eur Radiol. doi:10.1007/s00330-011-2162-y Bauer RW, Kramer S, Renker M, Schell B, Larson MC, Beeres M, Lehnert T, Jacobi V, Vogl TJ, Kerl JM (2011) Dose and image quality at CT pulmonary angiography-comparison of first and second generation dual-energy CT and 64-slice CT. Eur Radiol. doi:10.​1007/​s00330-011-2162-y
32.
go back to reference Bauer RW, Frellesen C, Renker M, Schell B, Lehnert T, Ackermann H, Schoepf UJ, Jacobi V, Vogl TJ, Kerl JM (2011) Dual energy CT pulmonary blood volume assessment in acute pulmonary embolism—correlation with D-dimer level, right heart strain and clinical outcome. Eur Radiol. doi:10.1007/s00330-011-2135-1 Bauer RW, Frellesen C, Renker M, Schell B, Lehnert T, Ackermann H, Schoepf UJ, Jacobi V, Vogl TJ, Kerl JM (2011) Dual energy CT pulmonary blood volume assessment in acute pulmonary embolism—correlation with D-dimer level, right heart strain and clinical outcome. Eur Radiol. doi:10.​1007/​s00330-011-2135-1
33.
go back to reference Björkdahl P, Nyman U (2010) Using 100- instead of 120-kVp computed tomography to diagnose pulmonary embolism almost halves the radiation dose with preserved diagnostic quality. Acta Radiol 51:260–270PubMedCrossRef Björkdahl P, Nyman U (2010) Using 100- instead of 120-kVp computed tomography to diagnose pulmonary embolism almost halves the radiation dose with preserved diagnostic quality. Acta Radiol 51:260–270PubMedCrossRef
Metadata
Title
Comparison of image quality and radiation dose of different pulmonary CTA protocols on a 128-slice CT: high-pitch dual source CT, dual energy CT and conventional spiral CT
Authors
Tobias De Zordo
Klemens von Lutterotti
Christian Dejaco
Peter F. Soegner
Renate Frank
Friedrich Aigner
Andrea S. Klauser
Christoph Pechlaner
U. Joseph Schoepf
Werner R. Jaschke
Gudrun M. Feuchtner
Publication date
01-02-2012
Publisher
Springer-Verlag
Published in
European Radiology / Issue 2/2012
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-011-2251-y

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