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European Radiology
Published in: European Radiology 10/2011

01-10-2011 | Vascular-Interventional

Improved detection of in-stent restenosis by blood pool agent-enhanced, high-resolution, steady-state magnetic resonance angiography

Authors: Christina M. Plank, Florian Wolf, Herbert Langenberger, Michael Weber, Dietrich Beitzke, Alfred Stadler, Martin Schillinger, Johannes Lammer, Christian Loewe

Published in: European Radiology | Issue 10/2011

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Abstract

Objective

The aim of this study was to assess whether visualisation of in-stent changes can be improved with high-resolution, steady-state, blood pool contrast-enhanced MR angiography compared with first-pass MR angiography. Intra-arterial digital subtraction angiography (DSA) served as the reference standard.

Methods

Twenty patients after stent placement in the superficial femoral artery (SFA) underwent MRA prior to reintervention. MRA of the SFA includes first-pass MRA as well as 3D high-resolution MRA in the steady state (SS-MRA) after injection of Gadofosveset trisodium. Sensitivity and specificity values for the detection of significant in-stent lesions by means of SS-MRA were calculated at the proximal, middle and distal stent segments in comparison to DSA. Kappa statistics were used to determine agreement between the two techniques.

Results

Sensitivity and specificity values for the detection of significant stenosis with SS-MRA reached 95% in the proximal, 100% in the middle and 100% in the distal stent segment. Kappa coefficients between SS-MRA and DSA were 0.789, 0.797 and 0.859 for the proximal, middle and distal segments, whereas the Kappa coefficients for FP-MRA were 0,211, 0,200 and 0,594 in these segments, respectively.

Conclusion

Detection of in stent stenosis is significantly improved using SS MRA, in comparison to state-of-the-art FP-MRA.
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Metadata
Title
Improved detection of in-stent restenosis by blood pool agent-enhanced, high-resolution, steady-state magnetic resonance angiography
Authors
Christina M. Plank
Florian Wolf
Herbert Langenberger
Michael Weber
Dietrich Beitzke
Alfred Stadler
Martin Schillinger
Johannes Lammer
Christian Loewe
Publication date
01-10-2011
Publisher
Springer-Verlag
Published in
European Radiology / Issue 10/2011
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-011-2145-z

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