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European Radiology
Published in: European Radiology 8/2011

01-08-2011 | Neuro

Flat-detector computed tomography in the assessment of intracranial stents: comparison with multi detector CT and conventional angiography in a new animal model

Authors: Tobias Struffert, Sabine Ott, Edyta Adamek, Marc Schwarz, Tobias Engelhorn, Stephan Kloska, Yu Deuerling-Zheng, Arnd Doerfler

Published in: European Radiology | Issue 8/2011

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Abstract

Objective

Careful follow up is necessary after intracranial stenting because in-stent restenosis (ISR) or residual stenosis (RS) is not rare. A minimally invasive follow-up imaging technique is desirable. The objective was to compare the visualisation of stents in Flat Detector-CT Angiography (FD-CTA) after intravenous contrast medium injection (i.v.) with Multi Detector Computed Tomography Angiography (MD-CTA) and Digital Subtracted Angiography (DSA) in an animal model.

Methods

Stents were implanted in the carotid artery of 12 rabbits. In 6 a residual stenosis (RS) was surgically created. Imaging was performed using FD-CTA, MD-CTA and DSA. Measurements of the inner and outer diameter and cross-section area of the stents were performed. Stenosis grade was calculated.

Results

In subjective evaluation FD-CTA was superior to MD-CTA. FD-CTA was more accurate compared with DSA than MD-CTA. Cross-sectional area of the stent lumen was significantly larger (p < 0.05) in FD-CTA in comparison to MD-CTA. Accurate evaluation of stenosis was impossible in MD-CTA. There was no statistically significant difference in the stenosis grade of DSA and FD-CTA.

Conclusion

Our results show that visualisation of stent and stenosis using intravenous FD-CTA compares favourably with DSA and may replace DSA in the follow-up of patients treated with intracranial stents.
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Metadata
Title
Flat-detector computed tomography in the assessment of intracranial stents: comparison with multi detector CT and conventional angiography in a new animal model
Authors
Tobias Struffert
Sabine Ott
Edyta Adamek
Marc Schwarz
Tobias Engelhorn
Stephan Kloska
Yu Deuerling-Zheng
Arnd Doerfler
Publication date
01-08-2011
Publisher
Springer-Verlag
Published in
European Radiology / Issue 8/2011
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-011-2093-7

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