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European Radiology
Published in: European Radiology 9/2010

01-09-2010 | Hepatobiliary-Pancreas

Hepatic focal nodular hyperplasia: contrast-enhanced ultrasound findings with emphasis on lesion size, depth and liver echogenicity

Authors: Tommaso Vincenzo Bartolotta, Adele Taibbi, Domenica Matranga, Giovanni Malizia, Roberto Lagalla, Massimo Midiri

Published in: European Radiology | Issue 9/2010

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Abstracts

Objective

To correlate contrast-enhanced ultrasound (CEUS) findings of hepatic focal nodular hyperplasia (FNH) with lesion size, depth and liver echogenicity and to compare CEUS with baseline US.

Methods

Two radiologists evaluated baseline US and CEUS examinations of 92 FNHs (mean size: 3.1 ± 1.7 cm) in 71 patients (59 women and 12 men) to detect the “spoke-wheel” sign, central scar and feeding vessel. The FNHs were grouped and analysed by dimension, depth and liver echogenicity.

Results

At least one sign could be detected at CEUS in 27 out of 36 (75%) FNHs larger than 3 cm and in 17 out of 56 (30%) FNH measuring 3 cm or less (p < 0.0001). No statistically significant differences were noted between lesion depth or liver echogenicity and detection rate of these signs at CEUS (p > 0.05) as well as between CEUS or baseline US/CD with regard to lesion size, depth or liver echogenicity (p > 0.05).

Conclusion

The detection rate of the central scar and spoke-wheel sign in FNH at CEUS is strongly dependent on lesion size and CEUS can confidently diagnose most FNHs larger than 3 cm.
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Metadata
Title
Hepatic focal nodular hyperplasia: contrast-enhanced ultrasound findings with emphasis on lesion size, depth and liver echogenicity
Authors
Tommaso Vincenzo Bartolotta
Adele Taibbi
Domenica Matranga
Giovanni Malizia
Roberto Lagalla
Massimo Midiri
Publication date
01-09-2010
Publisher
Springer-Verlag
Published in
European Radiology / Issue 9/2010
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-010-1775-x

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