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01-12-2009 | Cardiac

Diagnostic accuracy of high-pitch dual-source CT for the assessment of coronary stenoses: first experience

Authors: Sebastian Leschka, Paul Stolzmann, Lotus Desbiolles, Stephan Baumueller, Robert Goetti, Thomas Schertler, Hans Scheffel, Andre Plass, Volkmar Falk, Gudrun Feuchtner, Borut Marincek, Hatem Alkadhi

Published in: European Radiology | Issue 12/2009

Abstract

Objectives

The objective was to prospectively investigate the diagnostic accuracy of high-pitch (HP) dual-source computed tomography coronary angiography (CTCA) compared with catheter coronary angiography (CCA) for the diagnosis of significant coronary stenoses.

Methods

Thirty-five patients (seven women; mean age 62 ± 8 years) underwent both CTCA and CCA. CTCA was performed with a second-generation dual-source CT system permitting data acquisition at an HP of 3.4. Patients with heart rates >60 bpm were excluded from study enrolment. All coronary segments were evaluated by two blinded and independent observers with regard to image quality on a four-point scale (1: excellent to 4: non-diagnostic) and for the presence of significant coronary stenoses (defined as diameter narrowing exceeding 50%). CCA served as the standard of reference. Radiation dose values were calculated using the dose-length product.

Results

Diagnostic image quality was found in 99% of all segments (455/459). Non-diagnostic image quality occurred in a single patient with a sudden increase in heart rate immediately before and during CTCA. Taking segments with non-evaluative image quality as positive for disease, the sensitivity, specificity and positive and negative predictive values were 94, 96, 80 and 99% per segment and 100, 91, 88 and 100% per patient. The effective radiation dose was on average 0.9 ± 0.1 mSv.

Conclusion

In patients with heart rates ≤60 bpm, CTCA using the HP mode of the dual-source CT system is associated with high diagnostic accuracy for the assessment of coronary artery stenoses at sub-milliSievert doses.

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Title: Diagnostic accuracy of high-pitch dual-source CT for the assessment of coronary stenoses: first experience
Authors: Sebastian Leschka
Paul Stolzmann
Lotus Desbiolles
Stephan Baumueller
Robert Goetti
Thomas Schertler
Hans Scheffel
Andre Plass
Volkmar Falk
Gudrun Feuchtner
Borut Marincek
Hatem Alkadhi
Publication date: 01-12-2009
Publisher: Springer-Verlag
Published in: European Radiology / Issue 12/2009
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-009-1618-9

At a glance: The STEP trials

Springer Medicine

Diagnostic accuracy of high-pitch dual-source CT for the assessment of coronary stenoses: first experience

Abstract

Objectives

Methods

Results

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Objectives

Methods

Results

Conclusion

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