Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.
ADVANCED SEARCH
Log in
Top
European Radiology
Published in: European Radiology 3/2010

01-03-2010 | Gastrointestinal

Determining gastric cancer resectability by dynamic MDCT

Authors: Zilai Pan, Huan Zhang, Chao Yan, Lianjun Du, Bei Ding, Qi Song, Huawei Ling, Baisong Huang, Kemin Chen

Published in: European Radiology | Issue 3/2010

Login to get access

Abstract

Purpose

Multi-detector row CT (MDCT) has been widely used to detect primary lesions and to evaluate TNM staging. In this study we evaluated the accuracy of dynamic MDCT in the preoperative determination of the resectability of gastric cancer.

Methods

MDCT was used to image 350 cases of gastric cancer diagnosed by biopsy before surgery. MDCT findings regarding TNM staging and resectability were correlated with surgical and pathological findings.

Results

The accuracy of MDCT for staging gastric cancer was high, especially for tumour stage T1 (94.3%), lymph node stage N2 (87.3%), and for predicting distant metastases (>96.6%). When resectability was considered to be the outcome, the total accuracy of MDCT was 87.4%, sensitivity was 89.7% and specificity was 76.7%. Results showed high sensitivity for identifying peritoneal seeding (90.0%) and for predicting liver metastasis (80.0%).

Conclusion

Dynamic enhanced MDCT is useful for TNM staging of gastric cancers and for predicting tumour respectability preoperatively.
Literature
1.
Rossi M, Broglia L, Maccioni F, Bezzi M, Laghi A, Graziano P et al (1997) Hydro-CT in patients with gastric cancer: preoperative radiology staging. Eur Radiol 7:659–664CrossRefPubMed
2.
Takao M, Fukuda T (1998) Gastric cancer: evaluation of triphasic spiral CT and radiologic-pathologic correlation. J Comput Assist Tomogr 22:288–294CrossRefPubMed
3.
Yamada I, Saito N, Takeshita K, Yoshino N, Tetsumura A, Kumagai J, Shibuya H (2001) Early gastric carcinoma: evaluation with high-spatial-resolution MR Imaging in vitro. Radiology 220:115–121PubMed
4.
Horton KM, Fishman EK (2003) Current role of CT in imaging of the stomach. Radiographics 23:75–87CrossRefPubMed
5.
Tsuda K, Hori S, Murakami T, Nakamura H, Tomoda K, Nakanishi K, Shiozaki H (1995) Intramural invasion of gastric cancer: evaluation by CT with water-filling method. J Comput Assisted Tomogr 19:941–947CrossRef
6.
Kim HJ, Kim AY, Oh ST, Kim JS, Kim KW, Kim PN, Lee MG, Ha HK (2005) Gastric cancer staging at multi-detector row CT gastrography: comparison of transverse and volumetric CT scanning. Radiology 236:879–885CrossRefPubMed
7.
Chen CY, Hsu JS, Wu DC, Kang WY, Hsieh JS, Jaw TS, Wu MT, Liu GC (2007) Gastric cancer: preoperative local staging with 3D multi-detector row CT—correlation with surgical and histopathologic results. Radiology 242:472–482CrossRefPubMed
8.
Bhandari S, Shim CS, Kim JH, Jung IS, Cho JY, Lee JS, Lee MS, Kim BS (2004) Usefulness of three-dimensional, multidetector row CT (virtual gastroscopy and multiplanar reconstruction) in the evaluation of gastric cancer: a comparison with conventional endoscopy, EUS, and histopathology. Gastrointest Endosc 59:619–626CrossRefPubMed
9.
Shimizu K, Ito K, Matsunaga N, Shimizu A, Kawakami Y (2005) Diagnosis of gastric cancer with MDCT using the water-filling method and multiplanar reconstruction: CT-histologic correlation. AJR Am J Roentgenol 185:1152–1158CrossRefPubMed
10.
Shinohara T, Ohyama S, Yamaguchi T, Muto T, Kohno A, Kato Y, Urashima M (2005) Clinical value of multidetector row computed tomography in detecting lymph node metastasis of early gastric cancer. Eur J Surg Oncol 31:743–748CrossRefPubMed
11.
Habermann CR, Weiss F, Riecken R, Honarpisheh H, Bohnacker S, Staedtler C, Dieckmann C, Schoder V, Adam G (2004) Preoperative staging of gastric adenocarcinoma: comparison of helical CT and endoscopic US. Radiology 230:465–471CrossRefPubMed
12.
D’Elia F, Zingarelli A, Palli D, Grani M (2000) Hydro-dynamic CT preoperative staging of gastric cancer: correlation with pathological findings. A prospective study of 107 cases. Eur Radiol 10:1877–1885CrossRefPubMed
13.
Japanese Research Society for Gastric Carcinoma (1995) Japanese classification of gastric carcinoma, 1st English edn. Kanehara, Tokyo
14.
Fukuya T, Honda H, Kaneko K, Kuroiwa T, Yoshimitsu K, Irie H, Maehara Y, Masuda K (1997) Efficacy of helical CT in T-staging of gastric cancer. J Comput Assist Tomogr 21:73–81CrossRefPubMed
15.
Düx M, Richter GM, Hansmann J, Kuntz C, Kauffmann GW (1999) Helical hydro-CT for diagnosis and staging of gastric carcinoma. J Comput Assist Tomogr 23:913–922CrossRefPubMed
16.
Dorfman RE, Alpern MB, Gross BH, Sandler MA (1991) Upper abdominal lymph nodes: criteria for normal size determined with CT. Radiology 180:319–322PubMed
17.
Magnusson A, Anderson T (1989) Contrast enhancement of pathologic lymph nodes demonstrated by computed tomography. Acta Radiol 30:307–301CrossRefPubMed
18.
Fukuya T, Honda H, Hayashi T, Kaneko K, Tateshi Y, Ro T, Maehara Y, Tanaka M, Tsuneyoshi M, Masuda K (1995) Lymph-node metastases: efficacy for detection with helical CT in patients with gastric cancer. Radiology 197:705–711PubMed
19.
Zhu ZQ (2001) Choice of appropriate surgical method increase the quality of life for patient with early-stage gastric cancer [in Chinese]. Zhonghua Wei Chang Wai Ke Za Zhi 2:72–73
20.
Yin HR, Zhu ZQ, Lin YZ (2000) Surgical multimodality treatment in the treatment of advanced gastric cancer [in Chinese]. J Surg Concepts Pract 5:134–135
21.
Kwee RM, Kwee TC (2007) Imaging in local staging of gastric cancer: a systematic review. J Clin Oncol 25:2107–2116CrossRefPubMed
22.
Kumano S, Murakami T, Kim T, Hori M, Iannaccone R, Nakata S, Onishi H, Osuga K, Tomoda K, Catalano C, Nakamura H (2005) T staging of gastric cancer: role of multi-detector row CT. Radiology 237(3):961–966CrossRefPubMed
23.
Yang DM, Kim HC, Jin W, Ryu CW, Kang JH, Park CH, Kim HS, Jung DH (2007) 64 multidetector-row computed tomography for preoperative evaluation of gastric cancer: histological correlation. J Comput Assist Tomogr 31:98–103CrossRefPubMed
Metadata
Title
Determining gastric cancer resectability by dynamic MDCT
Authors
Zilai Pan
Huan Zhang
Chao Yan
Lianjun Du
Bei Ding
Qi Song
Huawei Ling
Baisong Huang
Kemin Chen
Publication date
01-03-2010
Publisher
Springer-Verlag
Published in
European Radiology / Issue 3/2010
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-009-1576-2

Other articles of this Issue 3/2010

European Radiology 3/2010 Go to the issue

Acknowledgement to Reviewers

The following individuals kindly reviewed manuscripts for European Radiology in the year 2009. The Editors greatly appreciate their benevolent and excellent support!

Computed Tomography

Analysis of the accuracy of high-resolution computed tomography techniques for the measurement of stapes prostheses

Breast

Carcinoma of the breast wire localisation post nuclear medicine sentinel lymph node imaging. Are radiologists receiving a significant dose?

Magnetic Resonance

Imaging of adult astrocytic brain tumours with 7 T MRI: preliminary results

Neuro

Sensitivity and reliability of language laterality assessment with a free reversed association task—a fMRI study

Interpretation Corner

Juxta-articular myxoma of the knee in a 5-year-old boy: a case report and review of the literature (2009: 12b)