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European Radiology
Published in: European Radiology 8/2009

01-08-2009 | Neuro

In vivo proton magnetic resonance spectroscopy of intraventricular tumours of the brain

Authors: Carles Majós, Carles Aguilera, Mònica Cos, Àngels Camins, Ana P. Candiota, Teresa Delgado-Goñi, Àlex Samitier, Sara Castañer, Juan J. Sánchez, David Mato, Juan J. Acebes, Carles Arús

Published in: European Radiology | Issue 8/2009

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Abstract

The aim of this study was to assess the usefulness of proton MR spectroscopy in the diagnosis of intraventricular tumours. Fifty-two intraventricular tumours pertaining to 16 different tumour types were derived from our database. All cases had single-voxel proton MR spectroscopy performed at TE at both 30 and 136 ms at 1.5 T. The Mann-Whitney U test was used to search for the most discriminative datapoints each tumour type. Characteristic trends were found for some groups: high Glx and Ala in meningiomas (p < 0.001 and p < 0.01, respectively), high mobile lipids in metastasis (p < 0.001), high Cho in PNET (p < 0.001), high mI + Gly in ependymoma (p < 0.001), high NAC (p < 0.01) in the absence of the normal brain parenchyma pattern in colloid cysts, and high mI/Gly and Ala in central neurocytoma. Proton MR spectroscopy provides additional metabolic information that could be useful in the diagnosis of intraventricular brain tumors.
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Metadata
Title
In vivo proton magnetic resonance spectroscopy of intraventricular tumours of the brain
Authors
Carles Majós
Carles Aguilera
Mònica Cos
Àngels Camins
Ana P. Candiota
Teresa Delgado-Goñi
Àlex Samitier
Sara Castañer
Juan J. Sánchez
David Mato
Juan J. Acebes
Carles Arús
Publication date
01-08-2009
Publisher
Springer-Verlag
Published in
European Radiology / Issue 8/2009
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-009-1357-y

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