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European Radiology
Published in: European Radiology 5/2009

01-05-2009 | Oncology

Automated measurement of lymph nodes: a phantom study

Authors: Sebastian Keil, Cedric Plumhans, Florian F. Behrendt, Sven Stanzel, Michael Suehling, Georg Mühlenbruch, Andreas H. Mahnken, Rolf W. Günther, Marco Das

Published in: European Radiology | Issue 5/2009

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Abstract

The purpose of this study was to assess the accuracy of automated nodal quantification in a phantom. MDCT of a phantom with 17 synthetic lymph nodes of different sizes (diameter 6.0–30.0 mm) was performed at varying tube currents, reconstruction kernels and slice thicknesses. RECIST diameter and volume were measured using an automated software tool. Results were compared with the reference diameter and volume by calculating the absolute percentage error (APE). Degree of agreement between software and reference measurements was evaluated by computing corresponding concordance correlation coefficients (CCC). Under varying tube currents the mean APE (CCC) varied between 5.18% and 10.12% (0.95–0.99) for RECIST diameter and between 7.22% and 16.21% (0.94–1.00) for the volume. At different reconstruction kernels the mean APE values ranged between 7.20% and 7.55% (0.99) (RECIST) and between 8.96% and 14.42% (1.00) (volume). With different slice thicknesses the mean APE values differed from 5.81% to 9.20% (0.97–0.99) (RECIST) and from 8.16% to 22.66% (0.99–1.00) (volume). Regarding RECIST criteria and volume, automated evaluation of lymph nodes in a phantom demonstrated a high accuracy under varying MDCT parameters.
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Metadata
Title
Automated measurement of lymph nodes: a phantom study
Authors
Sebastian Keil
Cedric Plumhans
Florian F. Behrendt
Sven Stanzel
Michael Suehling
Georg Mühlenbruch
Andreas H. Mahnken
Rolf W. Günther
Marco Das
Publication date
01-05-2009
Publisher
Springer-Verlag
Published in
European Radiology / Issue 5/2009
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-008-1254-9

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