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European Radiology
Published in: European Radiology 4/2008

01-04-2008 | Urogenital

Diffusion tensor imaging of the normal prostate at 3 Tesla

Authors: Bengi Gürses, Neslihan Kabakci, Arzu Kovanlikaya, Zeynep Firat, Ali Bayram, Aziz Müfit Uluð, İlhami Kovanlikaya

Published in: European Radiology | Issue 4/2008

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Abstract

The aim of this study was to assess the feasibility of diffusion tensor imaging (DTI) of the prostate and to determine normative fractional anisotropy (FA) and apparent diffusion coefficient (ADC) values of healthy prostate with a 3-Tesla magnetic resonance imaging (MRI) system. Thirty volunteers with a mean age of 28 (25–35) years were scanned with a 3-Tesla MRI (Intera Achieva; Philips, The Netherlands) system using a six-channel phased array coil. Initially, T2-weighted turbo spin-echo (TSE) axial images of the prostate were obtained. In two subjects, a millimetric hypointense signal change was detected in the peripheral zones on T2-weighted TSE images. These two subjects were excluded from the study. DTI with single-shot echo-planar imaging (ssEPI) was performed in the remaining 28 subjects. ADC and FA values were measured using the manufacturer supplied software by positioning 9-pixel ROIs on each zone. Differences between parameters of the central and peripheral zones were assessed. Mean ADC value of the central (1.220 ± 0.271 × 10−3 mm2/s) was found to be significantly lower when compared with the peripheral gland (1.610 ± 0.347 × 10−3 mm2/s) (P < 0.01). Mean FA of the central gland was significantly higher (0.26), compared with the peripheral gland (0.16) (P < 0.01). This study shows the feasibility of prostate DTI with a 3-Tesla MR system and the normative FA and ADC values of peripheral and central zones of the normal prostate. The results are compatible with the microstructural organization of the gland.
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Metadata
Title
Diffusion tensor imaging of the normal prostate at 3 Tesla
Authors
Bengi Gürses
Neslihan Kabakci
Arzu Kovanlikaya
Zeynep Firat
Ali Bayram
Aziz Müfit Uluð
İlhami Kovanlikaya
Publication date
01-04-2008
Publisher
Springer-Verlag
Published in
European Radiology / Issue 4/2008
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-007-0795-7

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