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Published in: European Radiology 7/2007

01-07-2007 | Urogenital

Cine MR imaging of uterine peristalsis in patients with endometriosis

Authors: Aki Kido, Kaori Togashi, Mizuki Nishino, Kanae Miyake, Takashi Koyama, Ryota Fujimoto, Kazuhiro Iwasaku, Shingo Fujii, Katsumi Hayakawa

Published in: European Radiology | Issue 7/2007

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Abstract

Endometriosis is one of the most important causes of infertility; however the precise mechanism by which it affects female fertility is unclear. The objective of this study was to study the functional aspects of the uterus by evaluating uterine contractility in patients with endometrial cysts of the ovary. The study population was recruited from two institutes and consisted of 26 women (periovulatory (10), luteal (13), and menstrual phase (3); age range: 19–51 years) with untreated endometriosis; the control group consisted of 12 healthy women (age range: 22–41 years). Cine MR imaging obtained by a 1.5T magnet was visually evaluated at 12× faster than real speed, focusing on the presence of uterine peristalsis, the direction and frequency of peristalsis, and the presence of sustained uterine contractions. Uterine peristalsis was identifiable in 3/10, 3/13, and 3/3 of the endometriosis patients in each menstrual cycle, respectively, and in 11/12, 3/12, and 5/12 of their control subjects. Peristaltic detection rate and frequency were significantly less for the endometriosis group than for the controls in the periovulatory phase only (p<0.05). Sustained contractions were recognized in 19/36 control subjects and in 13/26 endometriosis patients, but the difference was not significant. Uterine peristalsis appears to be suppressed during the periovulatory phase in patients with endometriosis, which may have an adverse effect on sperm transport.
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Literature
1.
go back to reference Gianetto-Berrutti A, Feyles V (2003) Endometriosis related to infertility. Minerva Ginecol 55:407–416PubMed Gianetto-Berrutti A, Feyles V (2003) Endometriosis related to infertility. Minerva Ginecol 55:407–416PubMed
2.
go back to reference Somigliana E, Vigano P, Rossi G, Carinelli S, Vignali M, Panina-Bordignon P (1999) Endometrial ability to implant in ectopic sites can be prevented by interleukin-12 in a murine model of endometriosis. Hum Reprod 14:2944–2950PubMedCrossRef Somigliana E, Vigano P, Rossi G, Carinelli S, Vignali M, Panina-Bordignon P (1999) Endometrial ability to implant in ectopic sites can be prevented by interleukin-12 in a murine model of endometriosis. Hum Reprod 14:2944–2950PubMedCrossRef
3.
go back to reference Schenken RS, Guzick DS (1997) Revised endometriosis classification: 1996. Fertil Steril 67:815–816PubMedCrossRef Schenken RS, Guzick DS (1997) Revised endometriosis classification: 1996. Fertil Steril 67:815–816PubMedCrossRef
4.
go back to reference D’Hooghe TM, Hill JA (1996) Endometriosis. In: Berek J (ed) Novak’s gynecology. Lippincott Williams and Wilkins & Wilkins, Philadelphia, pp 887–914 D’Hooghe TM, Hill JA (1996) Endometriosis. In: Berek J (ed) Novak’s gynecology. Lippincott Williams and Wilkins & Wilkins, Philadelphia, pp 887–914
5.
go back to reference Lyons EA, Taylor PJ, Zheng XH, Ballard G, Levi CS, Kredentser JV (1991) Characterization of subendometrial myometrial contractions throughout the menstrual cycle in normal fertile women. Fertil Steril 55:771–774PubMed Lyons EA, Taylor PJ, Zheng XH, Ballard G, Levi CS, Kredentser JV (1991) Characterization of subendometrial myometrial contractions throughout the menstrual cycle in normal fertile women. Fertil Steril 55:771–774PubMed
6.
go back to reference Leyendecker G, Kunz G, Wildt L, Beil D, Deininger H (1996) Uterine hyperperistalsis and dysperistalsis as dysfunctions of the mechanism of rapid sperm transport in patients with endometriosis and infertility. Hum Reprod 11:1542–1551PubMed Leyendecker G, Kunz G, Wildt L, Beil D, Deininger H (1996) Uterine hyperperistalsis and dysperistalsis as dysfunctions of the mechanism of rapid sperm transport in patients with endometriosis and infertility. Hum Reprod 11:1542–1551PubMed
7.
go back to reference Ijland MM, Evers JL, Dunselman GA, van Katwijk C, Lo CR, Hoogland HJ (1996) Endometrial wavelike movements during the menstrual cycle. Fertil Steril 65:746–749PubMed Ijland MM, Evers JL, Dunselman GA, van Katwijk C, Lo CR, Hoogland HJ (1996) Endometrial wavelike movements during the menstrual cycle. Fertil Steril 65:746–749PubMed
8.
go back to reference de Vries K, Lyons EA, Ballard G, Levi CS, Lindsay DJ (1990) Contractions of the inner third of the myometrium. Am J Obstet Gynecol 162:679–682PubMed de Vries K, Lyons EA, Ballard G, Levi CS, Lindsay DJ (1990) Contractions of the inner third of the myometrium. Am J Obstet Gynecol 162:679–682PubMed
9.
go back to reference Nakai A, Togashi K, Ueda H, Yamaoka T, Fujii S, Konishi J (2001) Junctional zone on magnetic resonance imaging: continuous changes on ultrafast images. J Womens Imaging 3:89–93CrossRef Nakai A, Togashi K, Ueda H, Yamaoka T, Fujii S, Konishi J (2001) Junctional zone on magnetic resonance imaging: continuous changes on ultrafast images. J Womens Imaging 3:89–93CrossRef
10.
go back to reference Nakai A, Togashi K, Yamaoka T, Fujiwara T, Ueda H, Koyama T, Kobayashi H, Kagimura T, Fujii S, Konishi J (2003) Uterine peristalsis shown on cine MR imaging using ultrafast sequence. J Magn Reson Imaging 18:726–733PubMedCrossRef Nakai A, Togashi K, Yamaoka T, Fujiwara T, Ueda H, Koyama T, Kobayashi H, Kagimura T, Fujii S, Konishi J (2003) Uterine peristalsis shown on cine MR imaging using ultrafast sequence. J Magn Reson Imaging 18:726–733PubMedCrossRef
11.
go back to reference Nakai A, Togashi K, Kosaka K, Kido A, Hiraga A, Fujiwara T, Koyama T, Fujii S (2004) Uterine peristalsis: comparison of transvaginal ultrasound and two different sequences of cine MR imaging. J Magn Reson Imaging 20:463–469PubMedCrossRef Nakai A, Togashi K, Kosaka K, Kido A, Hiraga A, Fujiwara T, Koyama T, Fujii S (2004) Uterine peristalsis: comparison of transvaginal ultrasound and two different sequences of cine MR imaging. J Magn Reson Imaging 20:463–469PubMedCrossRef
12.
go back to reference Kataoka M, Togashi K, Kido A, Nakai A, Fujiwara T, Koyama T, Fujii S (2005) Dysmenorrhea: evaluation with cine-mode-display MR imaging-initial experience. Radiology 235:124–131PubMedCrossRef Kataoka M, Togashi K, Kido A, Nakai A, Fujiwara T, Koyama T, Fujii S (2005) Dysmenorrhea: evaluation with cine-mode-display MR imaging-initial experience. Radiology 235:124–131PubMedCrossRef
13.
go back to reference Kinkel K, Chapron C, Balleyguier C, Fritel X, Dubuisson JB, Moreau JF (1999) Magnetic resonance imaging characteristics of deep endometriosis. Hum Reprod 14:1080–1086PubMedCrossRef Kinkel K, Chapron C, Balleyguier C, Fritel X, Dubuisson JB, Moreau JF (1999) Magnetic resonance imaging characteristics of deep endometriosis. Hum Reprod 14:1080–1086PubMedCrossRef
14.
go back to reference Bazot M, Darai E, Hourani R, Thomassin I, Cortez A, Uzan S, Buy JN (2004) Deep pelvic endometriosis: MR imaging for diagnosis and prediction of extension of disease. Radiology 232:379–389PubMedCrossRef Bazot M, Darai E, Hourani R, Thomassin I, Cortez A, Uzan S, Buy JN (2004) Deep pelvic endometriosis: MR imaging for diagnosis and prediction of extension of disease. Radiology 232:379–389PubMedCrossRef
15.
go back to reference Kinkel K, Frei KA, Balleyguier C, Chapron C (2006) Diagnosis of endometriosis with imaging: a review. Eur Radiol 2:285–298, Feb;16CrossRef Kinkel K, Frei KA, Balleyguier C, Chapron C (2006) Diagnosis of endometriosis with imaging: a review. Eur Radiol 2:285–298, Feb;16CrossRef
16.
go back to reference Togashi K, Nishimura K, Kimura I, Tsuda Y, Yamashita K, Shibata T, Nakano Y, Konishi J, Konishi I, Mori T (1991) Endometrial cysts: diagnosis with MR imaging. Radiology 180:73–78PubMed Togashi K, Nishimura K, Kimura I, Tsuda Y, Yamashita K, Shibata T, Nakano Y, Konishi J, Konishi I, Mori T (1991) Endometrial cysts: diagnosis with MR imaging. Radiology 180:73–78PubMed
17.
go back to reference Togashi K, Kawakami S, Kimura I, Asato R, Takakura K, Mori T, Konishi J (1993) Sustained uterine contractions: a cause of hypointense myometrial bulging. Radiology 187:707–710PubMed Togashi K, Kawakami S, Kimura I, Asato R, Takakura K, Mori T, Konishi J (1993) Sustained uterine contractions: a cause of hypointense myometrial bulging. Radiology 187:707–710PubMed
18.
go back to reference Togashi K, Kawakami S, Kimura I, Asato R, Okumura R, Fukuoka M, Mori T, Konishi J (1993) Uterine contractions: possible diagnostic pitfall at MR imaging. J Magn Reson Imaging 3:889–893PubMedCrossRef Togashi K, Kawakami S, Kimura I, Asato R, Okumura R, Fukuoka M, Mori T, Konishi J (1993) Uterine contractions: possible diagnostic pitfall at MR imaging. J Magn Reson Imaging 3:889–893PubMedCrossRef
19.
go back to reference Masui T, Katayama M, Kobayashi S, Shimizu S, Nozaki A, Sakahara H (2003) Pseudolesions related to uterine contraction: characterization with multiphase-multisection T2-weighted MR imaging. Radiology 227:345–352PubMedCrossRef Masui T, Katayama M, Kobayashi S, Shimizu S, Nozaki A, Sakahara H (2003) Pseudolesions related to uterine contraction: characterization with multiphase-multisection T2-weighted MR imaging. Radiology 227:345–352PubMedCrossRef
20.
go back to reference Kido A, Nishiura M, Togashi K, Nakai A, Fujiwara T, Kataoka ML, Koyama T, Fujii S, Asada N (2005) A semiautomated technique for evaluation of uterine peristalsis. J Magn Reson Imaging 21:249–257PubMedCrossRef Kido A, Nishiura M, Togashi K, Nakai A, Fujiwara T, Kataoka ML, Koyama T, Fujii S, Asada N (2005) A semiautomated technique for evaluation of uterine peristalsis. J Magn Reson Imaging 21:249–257PubMedCrossRef
21.
go back to reference Fujiwara T, Togashi K, Yamaoka T, Nakai A, Kido A, Nishio S, Yamamoto T, Kitagaki H, Fujii S (2004) Kinematics of the uterus: cine mode MR imaging. Radiographics 24:e19PubMedCrossRef Fujiwara T, Togashi K, Yamaoka T, Nakai A, Kido A, Nishio S, Yamamoto T, Kitagaki H, Fujii S (2004) Kinematics of the uterus: cine mode MR imaging. Radiographics 24:e19PubMedCrossRef
22.
go back to reference Leyendecker G, Kunz G, Noe M, Herbertz M, Mall G (1998) Endometriosis: a dysfunction and disease of the archimetra. Hum Reprod Update 4:752–762PubMedCrossRef Leyendecker G, Kunz G, Noe M, Herbertz M, Mall G (1998) Endometriosis: a dysfunction and disease of the archimetra. Hum Reprod Update 4:752–762PubMedCrossRef
23.
go back to reference Kido A, Togashi K, Nakai A, Kataoka M, Fujiwara T, Kobayashi A (2003) Circadian rhythm of uterine peristalsis. In: Proc Int Soc Magn Reson Med, vol 11. International Society for Magnetic Resonance in Medicine, Toronto, p 464 Kido A, Togashi K, Nakai A, Kataoka M, Fujiwara T, Kobayashi A (2003) Circadian rhythm of uterine peristalsis. In: Proc Int Soc Magn Reson Med, vol 11. International Society for Magnetic Resonance in Medicine, Toronto, p 464
24.
go back to reference Salamanca A, Beltran E (1995) Subendometrial contractility in menstrual phase visualized by transvaginal sonography in patients with endometriosis. Fertil Steril 64:193–195PubMed Salamanca A, Beltran E (1995) Subendometrial contractility in menstrual phase visualized by transvaginal sonography in patients with endometriosis. Fertil Steril 64:193–195PubMed
25.
go back to reference Sampson JA, Albany NY (1927) Peritoneal endometriosis due to the menstrual dissemination. Am J Obstet Gynecol 14:422–429 Sampson JA, Albany NY (1927) Peritoneal endometriosis due to the menstrual dissemination. Am J Obstet Gynecol 14:422–429
26.
go back to reference Blumenkrantz MJ, Gallagher N, Bashore RA, Tenckhoff H (1981) Retrograde menstruation in women undergoing chronic peritoneal dialysis. Obstet Gynecol 57:667–670PubMed Blumenkrantz MJ, Gallagher N, Bashore RA, Tenckhoff H (1981) Retrograde menstruation in women undergoing chronic peritoneal dialysis. Obstet Gynecol 57:667–670PubMed
Metadata
Title
Cine MR imaging of uterine peristalsis in patients with endometriosis
Authors
Aki Kido
Kaori Togashi
Mizuki Nishino
Kanae Miyake
Takashi Koyama
Ryota Fujimoto
Kazuhiro Iwasaku
Shingo Fujii
Katsumi Hayakawa
Publication date
01-07-2007
Publisher
Springer-Verlag
Published in
European Radiology / Issue 7/2007
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-006-0494-9

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